FR2769853B1 - Nouveau procede d'obtention de microspheres et les produits ainsi realises - Google Patents

Nouveau procede d'obtention de microspheres et les produits ainsi realises

Info

Publication number
FR2769853B1
FR2769853B1 FR9713155A FR9713155A FR2769853B1 FR 2769853 B1 FR2769853 B1 FR 2769853B1 FR 9713155 A FR9713155 A FR 9713155A FR 9713155 A FR9713155 A FR 9713155A FR 2769853 B1 FR2769853 B1 FR 2769853B1
Authority
FR
France
Prior art keywords
products
produced
new process
obtaining microspheres
microspheres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9713155A
Other languages
English (en)
Other versions
FR2769853A1 (fr
Inventor
Costanzo Francis Di
Gerard Cousin
Etienne Bruna
Francoise Di Costanzo Ragot
Jean Philippe Auriat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Prographarm SA
Original Assignee
Laboratories Prographarm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Prographarm SA filed Critical Laboratories Prographarm SA
Priority to FR9713155A priority Critical patent/FR2769853B1/fr
Priority to FR9813150A priority patent/FR2769854B1/fr
Priority to CA002287485A priority patent/CA2287485A1/fr
Priority to US09/331,465 priority patent/US20020076444A1/en
Priority to EP98951535A priority patent/EP0966270A1/fr
Priority to JP52338399A priority patent/JP2001507044A/ja
Priority to AU97512/98A priority patent/AU9751298A/en
Priority to PCT/FR1998/002251 priority patent/WO1999020254A1/fr
Publication of FR2769853A1 publication Critical patent/FR2769853A1/fr
Application granted granted Critical
Publication of FR2769853B1 publication Critical patent/FR2769853B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
FR9713155A 1997-10-21 1997-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises Expired - Fee Related FR2769853B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9713155A FR2769853B1 (fr) 1997-10-21 1997-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
FR9813150A FR2769854B1 (fr) 1997-10-21 1998-10-20 Nouveau procede d'obtention de microspheres et les produits ainsi realises
US09/331,465 US20020076444A1 (en) 1997-10-21 1998-10-21 Novel method for obtaining microspheres and resulting products
EP98951535A EP0966270A1 (fr) 1997-10-21 1998-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
CA002287485A CA2287485A1 (fr) 1997-10-21 1998-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
JP52338399A JP2001507044A (ja) 1997-10-21 1998-10-21 微粒子の新規製造方法と、それによって得られた製品
AU97512/98A AU9751298A (en) 1997-10-21 1998-10-21 Novel method for obtaining microspheres and resulting products
PCT/FR1998/002251 WO1999020254A1 (fr) 1997-10-21 1998-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9713155A FR2769853B1 (fr) 1997-10-21 1997-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises

Publications (2)

Publication Number Publication Date
FR2769853A1 FR2769853A1 (fr) 1999-04-23
FR2769853B1 true FR2769853B1 (fr) 2000-01-28

Family

ID=9512454

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9713155A Expired - Fee Related FR2769853B1 (fr) 1997-10-21 1997-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises

Country Status (1)

Country Link
FR (1) FR2769853B1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257744B2 (en) 2000-07-07 2012-09-04 Laboratorios Farmacéuticos Rovi, S.A. Pharmaceutical forms for the release of active compounds
FR2811227A1 (fr) 2000-07-07 2002-01-11 Philippe Maincent Vecteurs particulaires destines a ameliorer l'absorption orale de principes actifs
US8802156B2 (en) 2007-11-14 2014-08-12 Laboratorios Farmacéuticos Rovi, S.A. Pharmaceutical forms for the release of active compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62126122A (ja) * 1985-11-27 1987-06-08 Showa Shinyaku Kk 表面コ−テイングされたイブプロフエン顆粒の製法

Also Published As

Publication number Publication date
FR2769853A1 (fr) 1999-04-23

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20060630