FR2716460B1 - Modèle animal de la maladie d'Alzheimer, préparation et utilisations. - Google Patents
Modèle animal de la maladie d'Alzheimer, préparation et utilisations.Info
- Publication number
- FR2716460B1 FR2716460B1 FR9401922A FR9401922A FR2716460B1 FR 2716460 B1 FR2716460 B1 FR 2716460B1 FR 9401922 A FR9401922 A FR 9401922A FR 9401922 A FR9401922 A FR 9401922A FR 2716460 B1 FR2716460 B1 FR 2716460B1
- Authority
- FR
- France
- Prior art keywords
- alzheimer
- disease
- preparation
- animal model
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0312—Animal model for Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9401922A FR2716460B1 (fr) | 1994-02-21 | 1994-02-21 | Modèle animal de la maladie d'Alzheimer, préparation et utilisations. |
PCT/FR1995/000187 WO1995022616A1 (fr) | 1994-02-21 | 1995-02-17 | Modele animal de la maladie d'alzheimer, preparation et utilisations |
EP95909839A EP0734447A1 (fr) | 1994-02-21 | 1995-02-17 | Modele animal de la maladie d'alzheimer, preparation et utilisations |
JP7521633A JPH09509059A (ja) | 1994-02-21 | 1995-02-17 | アルツハイマー病の動物モデル、調製方法および使用 |
AU18156/95A AU1815695A (en) | 1994-02-21 | 1995-02-17 | Animal model of the alzheimer disease, preparation and utilisations |
CA 2182724 CA2182724A1 (fr) | 1994-02-21 | 1995-02-17 | Modele animal de la maladie d'alzheimer, preparation et utilisations |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9401922A FR2716460B1 (fr) | 1994-02-21 | 1994-02-21 | Modèle animal de la maladie d'Alzheimer, préparation et utilisations. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2716460A1 FR2716460A1 (fr) | 1995-08-25 |
FR2716460B1 true FR2716460B1 (fr) | 2002-08-09 |
Family
ID=9460258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9401922A Expired - Fee Related FR2716460B1 (fr) | 1994-02-21 | 1994-02-21 | Modèle animal de la maladie d'Alzheimer, préparation et utilisations. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0734447A1 (fr) |
JP (1) | JPH09509059A (fr) |
AU (1) | AU1815695A (fr) |
CA (1) | CA2182724A1 (fr) |
FR (1) | FR2716460B1 (fr) |
WO (1) | WO1995022616A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9706463D0 (en) * | 1997-03-27 | 1997-05-14 | Medical Res Council | A model of inflamation in the central nervous system for use in the study of disease |
CA2392299A1 (fr) * | 1999-12-10 | 2001-06-14 | Victor Rivera | Procedes d'expression haut niveau de genes chez des primates |
US20040093623A1 (en) * | 2000-12-20 | 2004-05-13 | Zeger Debyser | Non-human animal disease models |
KR101890978B1 (ko) | 2014-06-17 | 2018-08-24 | 서울대학교산학협력단 | 알츠하이머 질환 모델용 형질전환 돼지 및 이의 용도 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8927908D0 (en) * | 1989-12-09 | 1990-02-14 | Medical Res Council | Improvements in or relating to alzheimer's disease |
EP0451700A1 (fr) * | 1990-04-10 | 1991-10-16 | Miles Inc. | Minigènes APP recombinants pour l'expression dans des souris transgéniques comme modèles de la maladie d'Alzheimer |
WO1993014200A1 (fr) * | 1992-01-07 | 1993-07-22 | Tsi Corporation | Modeles d'animaux transgeniques utilises pour tester des traitements potentiels relatifs a la maladie d'alzheimer |
ATE404683T1 (de) * | 1992-09-25 | 2008-08-15 | Aventis Pharma Sa | Adenovirus vektoren für die übertragung fremder gene in zellen des zentralen nervensystems, insbesondere im gehirn |
GB9220777D0 (en) * | 1992-10-02 | 1992-11-18 | Univ Leicester | Oligonucleotide probes |
-
1994
- 1994-02-21 FR FR9401922A patent/FR2716460B1/fr not_active Expired - Fee Related
-
1995
- 1995-02-17 CA CA 2182724 patent/CA2182724A1/fr not_active Abandoned
- 1995-02-17 JP JP7521633A patent/JPH09509059A/ja not_active Ceased
- 1995-02-17 WO PCT/FR1995/000187 patent/WO1995022616A1/fr not_active Application Discontinuation
- 1995-02-17 EP EP95909839A patent/EP0734447A1/fr not_active Withdrawn
- 1995-02-17 AU AU18156/95A patent/AU1815695A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1995022616A1 (fr) | 1995-08-24 |
FR2716460A1 (fr) | 1995-08-25 |
EP0734447A1 (fr) | 1996-10-02 |
CA2182724A1 (fr) | 1995-08-24 |
AU1815695A (en) | 1995-09-04 |
JPH09509059A (ja) | 1997-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
ST | Notification of lapse |
Effective date: 20051031 |