AU1815695A - Animal model of the alzheimer disease, preparation and utilisations - Google Patents

Animal model of the alzheimer disease, preparation and utilisations

Info

Publication number
AU1815695A
AU1815695A AU18156/95A AU1815695A AU1815695A AU 1815695 A AU1815695 A AU 1815695A AU 18156/95 A AU18156/95 A AU 18156/95A AU 1815695 A AU1815695 A AU 1815695A AU 1815695 A AU1815695 A AU 1815695A
Authority
AU
Australia
Prior art keywords
utilisations
preparation
animal model
alzheimer disease
alzheimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU18156/95A
Inventor
Pascal Barneoud
Pia Delaere
Luc Mercken
Michel Perricaudet
Laurent Pradier
Emmanuelle Vigne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of AU1815695A publication Critical patent/AU1815695A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A01K2267/0312—Animal model for Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU18156/95A 1994-02-21 1995-02-17 Animal model of the alzheimer disease, preparation and utilisations Abandoned AU1815695A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9401922A FR2716460B1 (en) 1994-02-21 1994-02-21 Animal model of Alzheimer's disease, preparation and uses.
FR9401922 1994-02-21
PCT/FR1995/000187 WO1995022616A1 (en) 1994-02-21 1995-02-17 Animal model of the alzheimer disease, preparation and utilisations

Publications (1)

Publication Number Publication Date
AU1815695A true AU1815695A (en) 1995-09-04

Family

ID=9460258

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18156/95A Abandoned AU1815695A (en) 1994-02-21 1995-02-17 Animal model of the alzheimer disease, preparation and utilisations

Country Status (6)

Country Link
EP (1) EP0734447A1 (en)
JP (1) JPH09509059A (en)
AU (1) AU1815695A (en)
CA (1) CA2182724A1 (en)
FR (1) FR2716460B1 (en)
WO (1) WO1995022616A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9706463D0 (en) * 1997-03-27 1997-05-14 Medical Res Council A model of inflamation in the central nervous system for use in the study of disease
JP2003516147A (en) * 1999-12-10 2003-05-13 アリアド ジーン セラピューティクス インコーポレイテッド High levels of gene expression in primates
US20040093623A1 (en) * 2000-12-20 2004-05-13 Zeger Debyser Non-human animal disease models
KR101890978B1 (en) 2014-06-17 2018-08-24 서울대학교산학협력단 Transgenic cloned porcine Models for alzheimer's disease and the Use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927908D0 (en) * 1989-12-09 1990-02-14 Medical Res Council Improvements in or relating to alzheimer's disease
EP0451700A1 (en) * 1990-04-10 1991-10-16 Miles Inc. Recombinant APP minigenes for expression in transgenic mice as models for Alzheimers's disease
ES2204899T3 (en) * 1992-01-07 2004-05-01 Elan Pharmaceuticals, Inc. MODELS OF TRANSGENIC ANIMALS FOR ALZHEIMER'S DISEASE.
DE69334238D1 (en) * 1992-09-25 2008-09-25 Aventis Pharma Sa ADENOVIRUS VECTORS FOR THE TRANSMISSION OF FOREIGN GENES IN CELLS OF THE CENTRAL NERVOUS SYSTEM, ESPECIALLY IN THE BRAIN
GB9220777D0 (en) * 1992-10-02 1992-11-18 Univ Leicester Oligonucleotide probes

Also Published As

Publication number Publication date
FR2716460A1 (en) 1995-08-25
WO1995022616A1 (en) 1995-08-24
EP0734447A1 (en) 1996-10-02
FR2716460B1 (en) 2002-08-09
JPH09509059A (en) 1997-09-16
CA2182724A1 (en) 1995-08-24

Similar Documents

Publication Publication Date Title
AU5278590A (en) Animal model for benign prostatic disease
AU2808295A (en) Aqueous fluoropolymer emulsion and process for producing the same
AU4270596A (en) Human phosphodiesterase type ivc, and its production and use
GB2270919B (en) Aqueous wax and silicone dispersions,their production and use
AU4388696A (en) Biocidal alcohols, their production and their use
EP0674834A3 (en) Pretzel and method for preparation of the same.
AU1280799A (en) Non-transgenic animal model of alzheimer's disease
AU2267795A (en) Pyrazolecarboxylic acid derivative and plant disease control agent
AU1815695A (en) Animal model of the alzheimer disease, preparation and utilisations
IL135520A0 (en) 8-azabicyclo [3.2.1.] octane-3-methanamine derivatives, their preparation and their therapeutic application
ZA967537B (en) Novel carboxylic acid derivatives, their preparation and use.
ZA963197B (en) Pesticide formulations and process for the manufacture thereof
AU695918B2 (en) Iminooxybenzylcrotonate esters, their preparation and their use
AU4725697A (en) Model mouse for human diseases
IL112822A0 (en) Carbamoylcarboxamides, their preparation and their use as fungicides
EP0755671A4 (en) Dermatologic preparation
GB9124492D0 (en) Hoof hardeners,waterproofers and methods
AUPM727194A0 (en) Animal fat assessment
HUP0002895A3 (en) 3-azabicyclo[3.1.0]hexanes, method for producing the same, and their use
AU5148896A (en) Hydrazonoacetic acid amides and the use thereof as pesticide s
AU6886398A (en) Transgenic model and treatment for heart disease
AU3579795A (en) Fish farm
DK0828740T3 (en) 2-Azabicyclo [2.2.1] heptane derivatives, their preparation and use
AU2974695A (en) Nor-alpha-transbergamotenones, their production and use
AU6713100A (en) Animal model and uses thereof