FR2695826B1 - Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention. - Google Patents

Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.

Info

Publication number
FR2695826B1
FR2695826B1 FR9211422A FR9211422A FR2695826B1 FR 2695826 B1 FR2695826 B1 FR 2695826B1 FR 9211422 A FR9211422 A FR 9211422A FR 9211422 A FR9211422 A FR 9211422A FR 2695826 B1 FR2695826 B1 FR 2695826B1
Authority
FR
France
Prior art keywords
nomegestrol
derivatives
obtaining
methods
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9211422A
Other languages
English (en)
French (fr)
Other versions
FR2695826A1 (fr
Inventor
Michel Lanquetin
Jean-Louis Thomas
Jacques Paris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9211422A priority Critical patent/FR2695826B1/fr
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Priority to CA002122827A priority patent/CA2122827A1/fr
Priority to AU48229/93A priority patent/AU683423B2/en
Priority to KR1019940701665A priority patent/KR100255700B1/ko
Priority to DE69329790T priority patent/DE69329790D1/de
Priority to RU94026906A priority patent/RU2120797C1/ru
Priority to JP6507861A priority patent/JPH08506318A/ja
Priority to BR9305642A priority patent/BR9305642A/pt
Priority to FI942272A priority patent/FI942272A0/fi
Priority to HU9401395A priority patent/HUT67044A/hu
Priority to PCT/FR1993/000900 priority patent/WO1994006437A1/fr
Priority to US08/244,098 priority patent/US5565443A/en
Priority to CZ941164A priority patent/CZ284806B6/cs
Priority to AT93920896T priority patent/ATE198275T1/de
Priority to SK546-94A priority patent/SK54694A3/sk
Priority to EP93920896A priority patent/EP0613372B1/fr
Priority to RO94-00833A priority patent/RO115783B1/ro
Priority to PL93303780A priority patent/PL176120B1/pl
Priority to DZ930104A priority patent/DZ1717A1/fr
Priority to MA23291A priority patent/MA22978A1/fr
Priority to IL10703993A priority patent/IL107039A/en
Priority to TNTNSN93104A priority patent/TNSN93104A1/fr
Priority to ZA936964A priority patent/ZA936964B/xx
Priority to APAP/P/1993/000576A priority patent/AP497A/en
Priority to CN93114100A priority patent/CN1095667C/zh
Priority to YU60493A priority patent/YU60493A/sh
Priority to TW082108030A priority patent/TW381024B/zh
Priority to EC1993000986A priority patent/ECSP930986A/es
Publication of FR2695826A1 publication Critical patent/FR2695826A1/fr
Priority to OA60511A priority patent/OA09924A/fr
Priority to BG98776A priority patent/BG62317B1/bg
Priority to NO941900A priority patent/NO306238B1/no
Application granted granted Critical
Publication of FR2695826B1 publication Critical patent/FR2695826B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
FR9211422A 1992-09-21 1992-09-21 Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention. Expired - Fee Related FR2695826B1 (fr)

Priority Applications (31)

Application Number Priority Date Filing Date Title
FR9211422A FR2695826B1 (fr) 1992-09-21 1992-09-21 Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.
PL93303780A PL176120B1 (pl) 1992-09-21 1993-09-17 Środek farmaceutyczny będący implantem podskórnym i sposób wytwarzania środka farmaceutycznego będącego implantem podskórnym.
KR1019940701665A KR100255700B1 (ko) 1992-09-21 1993-09-17 노르메제스트롤 유도체를 기재로 하는 피하 이식편
DE69329790T DE69329790D1 (de) 1992-09-21 1993-09-17 Subkutane implantate bestehend aus nomgestrolderivaten
RU94026906A RU2120797C1 (ru) 1992-09-21 1993-09-17 Новые композиции в форме подкожных имплантатов на основе производных нормегестрола, способ их получения и применения
JP6507861A JPH08506318A (ja) 1992-09-21 1993-09-17 ノメゲストロール誘導体に基づく皮下埋め込み物
BR9305642A BR9305642A (pt) 1992-09-21 1993-09-17 Implantes subcutàneos baseados em derivados de nomegestrol
FI942272A FI942272A0 (fi) 1992-09-21 1993-09-17 Nomegestrolijohdannaisperustaiset ihonalaiset implantit
HU9401395A HUT67044A (en) 1992-09-21 1993-09-17 Subcutaneous implants containing nomegestrol derivatives and process for producing them
PCT/FR1993/000900 WO1994006437A1 (fr) 1992-09-21 1993-09-17 Implants sous-cutanes a base de derives de nomegestrol
US08/244,098 US5565443A (en) 1992-09-21 1993-09-17 Subcutaneous implants based on normegestrol derivatives
CZ941164A CZ284806B6 (cs) 1992-09-21 1993-09-17 Podkožní implantáty na bázi derivátů nomegesrolu
AT93920896T ATE198275T1 (de) 1992-09-21 1993-09-17 Subkutane implantate bestehend aus nomgestrolderivaten
SK546-94A SK54694A3 (en) 1992-09-21 1993-09-17 Subcutaneous implantants derivatives nomegestrol based
EP93920896A EP0613372B1 (fr) 1992-09-21 1993-09-17 Implants sous-cutanes a base de derives de nomegestrol
RO94-00833A RO115783B1 (ro) 1992-09-21 1993-09-17 Compozitie de implant subcutanat cu efect progestativ
CA002122827A CA2122827A1 (fr) 1992-09-21 1993-09-17 Implants sous-cutanes a base de derives du nomegestrol
AU48229/93A AU683423B2 (en) 1992-09-21 1993-09-17 Subcutaneous implants based on nomegestrol derivatives
DZ930104A DZ1717A1 (fr) 1992-09-21 1993-09-20 Nouvelles compositions pharmaceutiques à base de dérivés de nomegestrol et leur procédés d'obtention.
TNTNSN93104A TNSN93104A1 (fr) 1992-09-21 1993-09-20 Nouvelles compositions a base de derives de nomegestrol et leurs procedes d'obtention
MA23291A MA22978A1 (fr) 1992-09-21 1993-09-20 Nouvelles compositions a base de derives de nomegestrol et leurs procedes d'obtention.
IL10703993A IL107039A (en) 1992-09-21 1993-09-20 Subcutaneous implant compositions comprising nomegestrol derivatives and process for their production
CN93114100A CN1095667C (zh) 1992-09-21 1993-09-21 基于去甲基甲地孕酮衍生物的新颖组合物及其生产方法
YU60493A YU60493A (sh) 1992-09-21 1993-09-21 Novi preparati na bazi nomegestrol derivata i postupci za njihovo dobivanje
ZA936964A ZA936964B (en) 1992-09-21 1993-09-21 Pharmaceutical compositions containing derivatives of nomegestrol and their process of manufacture
APAP/P/1993/000576A AP497A (en) 1992-09-21 1993-09-21 Novel subcutaneous implants based on nomegestrol derivatives and the processes for their production.
TW082108030A TW381024B (en) 1992-09-21 1993-09-29 Contraceptive composition in the form of subcutaneous implants of a matrix type and a method for producing them
EC1993000986A ECSP930986A (es) 1992-09-21 1993-10-04 Nuevas composiciones basadas en derivados de nomegestrol y los procesos para su produccion
OA60511A OA09924A (fr) 1992-09-21 1994-05-11 Implants sous-cutanés à base de dérivés de nomegestrol
BG98776A BG62317B1 (bg) 1992-09-21 1994-05-16 Състави на базата на номогестролни производни, подкожниимпланти на базата на тези състави, методи за тяхното производствои използването им като контрацептив
NO941900A NO306238B1 (no) 1992-09-21 1994-05-20 Preparat i form av et subkutant implantat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211422A FR2695826B1 (fr) 1992-09-21 1992-09-21 Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.

Publications (2)

Publication Number Publication Date
FR2695826A1 FR2695826A1 (fr) 1994-03-25
FR2695826B1 true FR2695826B1 (fr) 1995-01-06

Family

ID=9433868

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9211422A Expired - Fee Related FR2695826B1 (fr) 1992-09-21 1992-09-21 Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.

Country Status (31)

Country Link
US (1) US5565443A (https=)
EP (1) EP0613372B1 (https=)
JP (1) JPH08506318A (https=)
KR (1) KR100255700B1 (https=)
CN (1) CN1095667C (https=)
AP (1) AP497A (https=)
AT (1) ATE198275T1 (https=)
AU (1) AU683423B2 (https=)
BG (1) BG62317B1 (https=)
BR (1) BR9305642A (https=)
CA (1) CA2122827A1 (https=)
CZ (1) CZ284806B6 (https=)
DE (1) DE69329790D1 (https=)
DZ (1) DZ1717A1 (https=)
EC (1) ECSP930986A (https=)
FI (1) FI942272A0 (https=)
FR (1) FR2695826B1 (https=)
HU (1) HUT67044A (https=)
IL (1) IL107039A (https=)
MA (1) MA22978A1 (https=)
NO (1) NO306238B1 (https=)
OA (1) OA09924A (https=)
PL (1) PL176120B1 (https=)
RO (1) RO115783B1 (https=)
RU (1) RU2120797C1 (https=)
SK (1) SK54694A3 (https=)
TN (1) TNSN93104A1 (https=)
TW (1) TW381024B (https=)
WO (1) WO1994006437A1 (https=)
YU (1) YU60493A (https=)
ZA (1) ZA936964B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
FR2737411B1 (fr) * 1995-08-01 1997-10-17 Theramex Nouveaux medicaments hormonaux et leur utilisation pour la correction des carences estrogeniques
FR2754179B1 (fr) * 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
FR2776191B1 (fr) * 1998-03-23 2002-05-31 Theramex Composition hormonale topique a effet systemique
US6117441A (en) * 1998-07-02 2000-09-12 The Population Council, Inc. Silicone core long term androgen delivery implant
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
GB2355728A (en) * 1999-10-27 2001-05-02 Anson Medical Ltd Tubular medical implants and methods of manufacture
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
ATE485837T1 (de) 2000-08-03 2010-11-15 Antares Pharma Ipl Ag Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
EP1411861B1 (en) 2001-06-29 2012-04-04 Medgraft Microtech, Inc. Biodegradable injectable implants and related methods of manufacture and use
SI2561860T1 (en) * 2002-05-31 2018-05-31 Titan Pharmaceuticals, Inc. An implantable polymeric device for prolonged release of buprenorphine
PT1610791E (pt) 2003-03-31 2011-05-23 Titan Pharmaceuticals Inc Dispositivo polim?rico implant?vel para liberta??o sustentada de agonista da dopamina
CA2526101A1 (en) * 2003-05-30 2004-12-23 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of nalmefene
ATE534373T1 (de) 2003-10-10 2011-12-15 Antares Pharma Ipl Ag Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
US7425340B2 (en) 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
WO2006078320A2 (en) 2004-08-04 2006-07-27 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
US8067399B2 (en) 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
CN101426475A (zh) 2006-04-21 2009-05-06 安塔雷斯制药Ipl股份公司 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法
FR2904213B1 (fr) * 2006-07-27 2008-10-10 Creaspine Soc Par Actions Simp Implant intervertebral destine a la fusion osseuse
WO2009085952A1 (en) 2007-12-20 2009-07-09 Brookwood Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
EP2140860A1 (en) * 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
GB2555373A (en) * 2016-08-23 2018-05-02 Reproductive Medicine And Gynaecology Associates Ltd Implant
US12582767B2 (en) 2021-12-30 2026-03-24 Taiyo Weber Compressible, minimally invasive implants and related systems and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147783A (en) * 1974-02-28 1979-04-03 Akzona Incorporated Oral pharmaceutical preparation
GB1515284A (en) * 1974-05-21 1978-06-21 Gastaud J Pharmaceutical compositions containing progestogens derived from the 17-alpha-hydroxy-19-nor-progesterone series
US4172132A (en) * 1977-07-26 1979-10-23 Schering Corporation 1,3,5(10),6,8,14-19-Nor-pregnahexaenes, their use as anti-psoriatic agents, and pharmaceutical formulations useful therefor
HU182775B (en) * 1981-10-15 1984-03-28 Richter Gedeon Vegyeszet Process for preparing new 3-chloro-pregnane derivatives
US5223492A (en) * 1987-10-27 1993-06-29 Nasraoui Nejib M Derivatives of 19-nor progesterone; process for producing them and the pharmaceutical compositions incorporating them
FR2664895B1 (fr) * 1990-07-20 1992-10-30 Theramex Laboratoire Nouveaux derives de la 6-methyl 19-nor progesterone, substitues en 3 et leur procede d'obtention.

Also Published As

Publication number Publication date
AU683423B2 (en) 1997-11-13
OA09924A (fr) 1994-09-15
US5565443A (en) 1996-10-15
BR9305642A (pt) 1996-01-09
RO115783B1 (ro) 2000-06-30
DZ1717A1 (fr) 2002-02-17
KR100255700B1 (ko) 2000-08-01
ATE198275T1 (de) 2001-01-15
NO306238B1 (no) 1999-10-11
YU60493A (sh) 1997-01-08
CA2122827A1 (fr) 1994-03-31
ECSP930986A (es) 1994-04-12
CN1094284A (zh) 1994-11-02
WO1994006437A1 (fr) 1994-03-31
FI942272A7 (fi) 1994-05-16
PL176120B1 (pl) 1999-04-30
BG98776A (bg) 1995-02-28
TW381024B (en) 2000-02-01
JPH08506318A (ja) 1996-07-09
NO941900D0 (no) 1994-05-20
CN1095667C (zh) 2002-12-11
SK54694A3 (en) 1994-10-05
CZ284806B6 (cs) 1999-03-17
EP0613372B1 (fr) 2000-12-27
RU2120797C1 (ru) 1998-10-27
ZA936964B (en) 1994-04-14
MA22978A1 (fr) 1994-04-01
FI942272L (fi) 1994-05-16
HU9401395D0 (en) 1994-08-29
NO941900L (no) 1994-05-24
AP497A (en) 1996-05-28
EP0613372A1 (fr) 1994-09-07
FI942272A0 (fi) 1994-05-16
FR2695826A1 (fr) 1994-03-25
IL107039A (en) 1999-01-26
HUT67044A (en) 1995-01-30
IL107039A0 (en) 1993-12-28
CZ116494A3 (en) 1995-03-15
AU4822993A (en) 1994-04-12
AP9300576A0 (https=) 1993-10-31
BG62317B1 (bg) 1999-08-31
TNSN93104A1 (fr) 1994-03-17
DE69329790D1 (de) 2001-02-01

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Legal Events

Date Code Title Description
ST Notification of lapse