FR2687411A1 - Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn. - Google Patents

Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn. Download PDF

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Publication number
FR2687411A1
FR2687411A1 FR9201608A FR9201608A FR2687411A1 FR 2687411 A1 FR2687411 A1 FR 2687411A1 FR 9201608 A FR9201608 A FR 9201608A FR 9201608 A FR9201608 A FR 9201608A FR 2687411 A1 FR2687411 A1 FR 2687411A1
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FR
France
Prior art keywords
vector
gene
rna
viral
polymerase iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9201608A
Other languages
English (en)
French (fr)
Other versions
FR2687411B1 (enExample
Inventor
Doglio Alain
Lefebvre Jean-Claude
Cagnon Laurence
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Université Côte d'Azur
Original Assignee
Université Côte d'Azur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Université Côte d'Azur filed Critical Université Côte d'Azur
Priority to FR9201608A priority Critical patent/FR2687411A1/fr
Publication of FR2687411A1 publication Critical patent/FR2687411A1/fr
Application granted granted Critical
Publication of FR2687411B1 publication Critical patent/FR2687411B1/fr
Granted legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9201608A 1992-02-13 1992-02-13 Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn. Granted FR2687411A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9201608A FR2687411A1 (fr) 1992-02-13 1992-02-13 Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201608A FR2687411A1 (fr) 1992-02-13 1992-02-13 Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn.

Publications (2)

Publication Number Publication Date
FR2687411A1 true FR2687411A1 (fr) 1993-08-20
FR2687411B1 FR2687411B1 (enExample) 1994-12-30

Family

ID=9426599

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9201608A Granted FR2687411A1 (fr) 1992-02-13 1992-02-13 Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn.

Country Status (1)

Country Link
FR (1) FR2687411A1 (enExample)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0647716A1 (fr) * 1993-07-06 1995-04-12 Universite De Nice-Sophia Antipolis Vecteur comportant un gène viral transcrit par l'ARN polymérase III
FR2714383A1 (fr) * 1993-12-29 1995-06-30 Centre Nat Rech Scient Contrôle de l'expression de gènes.
WO1996001315A1 (de) * 1994-07-04 1996-01-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Expressionskassette für die antisense- und die ribozym-expression
WO1996001314A3 (de) * 1994-07-04 1996-02-29 Max Planck Gesellschaft Ribozym-bibliothek, ihre herstellung und ihre verwendung
FR2743818A1 (fr) * 1996-01-23 1997-07-25 Agronomique Inst Nat Rech Constructions d'adn et vecteurs d'expression derives du gene de l'arn va i d'adenovirus
US6130092A (en) * 1994-07-04 2000-10-10 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. Ribozyme gene library and method for making
US6776986B1 (en) 1996-06-06 2004-08-17 Novartis Ag Inhibition of HIV-1 replication by antisense RNA expression
WO2004080378A3 (fr) * 2003-03-04 2005-04-21 Univ Nice Sophia Antipolis Methodes et outils pour le criblage d’arn actifs in cellulo

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387775A1 (de) * 1989-03-16 1990-09-19 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Genetische Einheiten zur Inhibierung der Funktion von RNA

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387775A1 (de) * 1989-03-16 1990-09-19 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Genetische Einheiten zur Inhibierung der Funktion von RNA

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EMBO JOURNAL. vol. 6, no. 10, 1987, EYNSHAM, OXFORD GB pages 3043 - 3047 JENNINGS, P.A. ET MOLLOY, P.L. 'Inhibition of SV40 replicon function by engineered antisense RNA transcribed by polymerase III' *
EMBO JOURNAL. vol. 8, no. 12, 1989, EYNSHAM, OXFORD GB pages 3861 - 3866 COTTEN, M. ET BIRNSTIEL, M.L. 'Ribozyme mediated destruction of RNA in vivo' *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0647716A1 (fr) * 1993-07-06 1995-04-12 Universite De Nice-Sophia Antipolis Vecteur comportant un gène viral transcrit par l'ARN polymérase III
FR2714383A1 (fr) * 1993-12-29 1995-06-30 Centre Nat Rech Scient Contrôle de l'expression de gènes.
WO1995018223A1 (fr) * 1993-12-29 1995-07-06 Centre National De La Recherche Scientifique Controle de l'expression de genes
US6133024A (en) * 1993-12-29 2000-10-17 Aventis Pharma S.A. Gene expression control
EP1939290A3 (fr) * 1993-12-29 2011-07-06 Centre National de la Recherche Scientifique Contrôle de l'expression de gènes
WO1996001315A1 (de) * 1994-07-04 1996-01-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Expressionskassette für die antisense- und die ribozym-expression
WO1996001314A3 (de) * 1994-07-04 1996-02-29 Max Planck Gesellschaft Ribozym-bibliothek, ihre herstellung und ihre verwendung
US6130092A (en) * 1994-07-04 2000-10-10 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. Ribozyme gene library and method for making
FR2743818A1 (fr) * 1996-01-23 1997-07-25 Agronomique Inst Nat Rech Constructions d'adn et vecteurs d'expression derives du gene de l'arn va i d'adenovirus
WO1997027309A1 (fr) * 1996-01-23 1997-07-31 Institut National De La Recherche Agronomique - I.N.R.A. Constructions d'adn et vecteurs d'expression derives du gene de l'arn va i d'adenovirus
US6776986B1 (en) 1996-06-06 2004-08-17 Novartis Ag Inhibition of HIV-1 replication by antisense RNA expression
WO2004080378A3 (fr) * 2003-03-04 2005-04-21 Univ Nice Sophia Antipolis Methodes et outils pour le criblage d’arn actifs in cellulo

Also Published As

Publication number Publication date
FR2687411B1 (enExample) 1994-12-30

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Effective date: 20091030