FR2669637A1 - Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent. - Google Patents

Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent. Download PDF

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Publication number
FR2669637A1
FR2669637A1 FR9014636A FR9014636A FR2669637A1 FR 2669637 A1 FR2669637 A1 FR 2669637A1 FR 9014636 A FR9014636 A FR 9014636A FR 9014636 A FR9014636 A FR 9014636A FR 2669637 A1 FR2669637 A1 FR 2669637A1
Authority
FR
France
Prior art keywords
general formula
alk
carbon atoms
hydroxy
pyrido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR9014636A
Other languages
English (en)
French (fr)
Inventor
Bisagni Emile
Nguyen Chi-Hung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9014636A priority Critical patent/FR2669637A1/fr
Priority to ZA919208A priority patent/ZA919208B/xx
Priority to IL100118A priority patent/IL100118A0/xx
Priority to EP92900717A priority patent/EP0558613A1/de
Priority to CA002096719A priority patent/CA2096719A1/fr
Priority to PT99579A priority patent/PT99579A/pt
Priority to KR1019930701548A priority patent/KR930702344A/ko
Priority to IE407291A priority patent/IE914072A1/en
Priority to JP4501700A priority patent/JPH06502861A/ja
Priority to HU9301501A priority patent/HUT64344A/hu
Priority to MX9102179A priority patent/MX9102179A/es
Priority to AU90650/91A priority patent/AU9065091A/en
Priority to PCT/FR1991/000926 priority patent/WO1992009602A1/fr
Publication of FR2669637A1 publication Critical patent/FR2669637A1/fr
Priority to NO93931765A priority patent/NO931765L/no
Priority to FI932332A priority patent/FI932332A/fi
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9014636A 1990-11-23 1990-11-23 Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent. Withdrawn FR2669637A1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR9014636A FR2669637A1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent.
ZA919208A ZA919208B (en) 1990-11-23 1991-11-21 New pyridobenzindole derivatives,their preparation and compositions containing them
IL100118A IL100118A0 (en) 1990-11-23 1991-11-21 Pyridobenzindole derivatives,their preparation and pharmaceutical compositions containing them
IE407291A IE914072A1 (en) 1990-11-23 1991-11-22 New pyridobenzindole derivatives, their preparation and¹compositions containing them
MX9102179A MX9102179A (es) 1990-11-23 1991-11-22 Nuevos derivados de piridobenzoindol,procedimiento para su preparacion y composicion farmaceutica que los contiene
PT99579A PT99579A (pt) 1990-11-23 1991-11-22 Processo de preparacao de derivados de piridobenzo-indolo e de composicoes farmaceuticas que os contem
KR1019930701548A KR930702344A (ko) 1990-11-23 1991-11-22 피리도 벤즈 인돌 유도체, 이의 제조방법 및 이를 함유하는 제약학적 조성물
EP92900717A EP0558613A1 (de) 1990-11-23 1991-11-22 Pyridobenzindol-derivate,ihre darstellung und pharmazeutische zusammensetzungen, die sie enthalten
JP4501700A JPH06502861A (ja) 1990-11-23 1991-11-22 ピリドベンズインドール誘導体、それらの製造およびそれらを含有している薬学的組成物
HU9301501A HUT64344A (en) 1990-11-23 1991-11-22 Methods for producing pyrido-benzo-indole derivatives and pharmaceutical preparatives containing them
CA002096719A CA2096719A1 (fr) 1990-11-23 1991-11-22 Derives de pyridobenzoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
AU90650/91A AU9065091A (en) 1990-11-23 1991-11-22 Pyridobenzoindole derivatives, their preparation method, and pharmaceutical compositions containing same
PCT/FR1991/000926 WO1992009602A1 (fr) 1990-11-23 1991-11-22 Derives de pyridobenzoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
NO93931765A NO931765L (no) 1990-11-23 1993-05-14 Pyridobenzoindol-derivater, deres fremstilling samt farmasoeytiske preparater inneholdende forbindelsen
FI932332A FI932332A (fi) 1990-11-23 1993-05-21 Nya pyridobenzoindolderivat, deras framstaellning och dessa innehaollande farmaceutiska preparat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9014636A FR2669637A1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent.

Publications (1)

Publication Number Publication Date
FR2669637A1 true FR2669637A1 (fr) 1992-05-29

Family

ID=9402518

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9014636A Withdrawn FR2669637A1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent.

Country Status (14)

Country Link
EP (1) EP0558613A1 (de)
JP (1) JPH06502861A (de)
KR (1) KR930702344A (de)
AU (1) AU9065091A (de)
CA (1) CA2096719A1 (de)
FI (1) FI932332A (de)
FR (1) FR2669637A1 (de)
HU (1) HUT64344A (de)
IE (1) IE914072A1 (de)
IL (1) IL100118A0 (de)
MX (1) MX9102179A (de)
PT (1) PT99579A (de)
WO (1) WO1992009602A1 (de)
ZA (1) ZA919208B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859474B1 (fr) 2003-09-04 2006-01-13 Centre Nat Rech Scient Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage
WO2011131636A1 (en) * 2010-04-19 2011-10-27 Institut Curie Combined treatment of cancer with benzo[e]pyridoindoles and dna-damaging agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, no. 2, février 1988, pages 398-405, Columbus, Ohio, US; E. BISAGNI et al.: "1-Amino-substituted 4-methyl-5H-pyrido[4,3-bÜindoles (gamma-carbolines) as tricyclic analogues of ellipticines: A new class of antineoplastic agents" *
JOURNAL OF MEDICINAL CHEMISTRY, vol. 33, no. 5, mai 1990, pages 1519-1528, Columbus, Ohio, US; E. BISAGNI et al.: "Synthesis and antitumor activity of 1-ÄÄ(dialkylamino)alkylÜaminoÜ-4-methyl-5H-pyrido[4,3-bÜbenzoÄeÜ-and-benzoÄgÜindoles. A new class of antineoplastic agents" *

Also Published As

Publication number Publication date
FI932332A0 (fi) 1993-05-21
HU9301501D0 (en) 1993-09-28
IE914072A1 (en) 1992-06-03
EP0558613A1 (de) 1993-09-08
KR930702344A (ko) 1993-09-08
MX9102179A (es) 1992-07-08
HUT64344A (en) 1993-12-28
IL100118A0 (en) 1992-08-18
PT99579A (pt) 1992-10-30
FI932332A (fi) 1993-05-21
AU9065091A (en) 1992-06-25
CA2096719A1 (fr) 1992-05-24
WO1992009602A1 (fr) 1992-06-11
JPH06502861A (ja) 1994-03-31
ZA919208B (en) 1992-08-26

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