FR2669224A1 - Hair-care compositions intended, in particular, for neutralizing the lactic acid of the scalp, and method of cosmetic treatment of the scalp - Google Patents

Hair-care compositions intended, in particular, for neutralizing the lactic acid of the scalp, and method of cosmetic treatment of the scalp Download PDF

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FR2669224A1
FR2669224A1 FR9014229A FR9014229A FR2669224A1 FR 2669224 A1 FR2669224 A1 FR 2669224A1 FR 9014229 A FR9014229 A FR 9014229A FR 9014229 A FR9014229 A FR 9014229A FR 2669224 A1 FR2669224 A1 FR 2669224A1
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scalp
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active substance
hair
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FR2669224B1 (en
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Contier Marcel
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to a hair-care composition, which contains an active substance containing at least one complex resulting from the combination, in aqueous or aqueous-alcoholic solution, of a dicarboxylic amino acid and a basic amino acid.

Description

COMPOSITIONS CAPILLAIRES, DESTINEES NOTAMMENT A LA
NEUTRALISATION DE L'ACIDE LACTIQUE DU CUIR CHEVELU ET
METHODE DE TRAITEMENT COSMETIQUE DU CUIR CHEVELU
L'invention a pour objet des compositions capillaires, destinées notamment à la neutralisation de l'acide lactique du cuir chevelu, un procédé de neutralisation de l'acide lactique du cuir chevelu, et une méthode de traitement cosmétique du cuir chevelu.HAIR COMPOSITIONS, ESPECIALLY FOR THE
NEUTRALIZATION OF LACTIC ACID FROM SCALP AND
COSMETIC TREATMENT METHOD FOR SCALP
The subject of the invention is hair compositions, intended in particular for neutralizing lactic acid from the scalp, a method for neutralizing lactic acid from the scalp, and a method for cosmetic treatment of the scalp.

L'expérience a montré que les sujets ayant une hyperhydrose anormale du cuir chevelu, présentaient une certaine fragilité de la résistance de leurs cheveux, ceux-ci s'arrachant facilement avec leur bulbe, contrairement aux cuirs chevelus traités par de l'aspartate de lysine, qui dans ce cas, cassaient sous l'action d'une traction, sans élimination du bulbe.Experience has shown that subjects with abnormal hyperhydrosis of the scalp, have a certain brittleness of the resistance of their hair, it is easily torn off with their bulb, unlike scalps treated with lysine aspartate , which in this case broke under the action of a traction, without eliminating the bulb.

I1 a été constaté que les éléments pilosébacés du cuir chevelu comportaient des canaux eccrines libérant un fluide sudoral contenant des teneurs variables d'acide lactique. I1 was found that the pilosebaceous elements of the scalp included eccrine channels releasing a sweat fluid containing variable contents of lactic acid.

Dans le cas d'hypersecrétion sudorale au niveau du cuir chevelu, il y a production élevée d'acide lactique qui provoque des dégradations biochimiques des constituants du bulbe pileux, conduisant à une perturbation de la biosynthèse de la fibre kératinique, histologiquement visible.In the case of sweat hypersecretion in the scalp, there is a high production of lactic acid which causes biochemical degradations of the constituents of the hair bulb, leading to a disturbance in the biosynthesis of the keratin fiber, which is histologically visible.

Il apparaît donc intéressant de neutraliser les effets néfastes de l'acide lactique au niveau du cuir chevelu cette action de neutralisation ne devant pas interférer dans le processus de secrétion sudorale, ni modifier en aucune façon, la fonction émonctoire et thermorégulatrice. It therefore appears interesting to neutralize the harmful effects of lactic acid on the scalp. This neutralizing action should not interfere in the process of sweat secretion, nor modify in any way, the emunctory and thermoregulatory function.

La présente invention a pour objet des compositions capillaires, destinées notamment à neutraliser l'action de l'acide lactique.The present invention relates to hair compositions, intended in particular to neutralize the action of lactic acid.

La présente invention a également pour objet de proposer une méthode de traitement cosmétique du cuir chevelu par neutralisation de l'acide lactique secrété par les glandes eccrines du cuir chevelu, par applications de compostions capillaires appropriées.Another object of the present invention is to propose a method of cosmetic treatment of the scalp by neutralization of the lactic acid secreted by the eccrine glands of the scalp, by applications of appropriate capillary compositions.

Les compositions capillaires de l'invention sont caractérisées en ce qu'elles contiennent une substance active contenant au moins un complexe résultant de l'association , en solution aqueuse ou hydroalcoolique, d'un acide aminé dicarboxylique et d'un acide aminé basique.The hair compositions of the invention are characterized in that they contain an active substance containing at least one complex resulting from the combination, in aqueous or hydroalcoholic solution, of an amino acid dicarboxylic acid and a basic amino acid.

Des compositions capillaires avantageuses de l'invention sont telles que leur substance active est constituée par l'un au moins des complexes suivants - aspartate de lysine - aspartate d'arginine - glutamate de lysine - glutamate d'arginine avantageusement l'aspartate de lysine.Advantageous hair compositions of the invention are such that their active substance consists of at least one of the following complexes - lysine aspartate - arginine aspartate - lysine glutamate - arginine glutamate advantageously lysine aspartate.

La lysine est un acide aminé basique du fait de la présence d'une fonction NH2 libre et active en position z . Une solution à 5% de lysine possede un pH voisin de 10.Lysine is a basic amino acid due to the presence of a free and active NH2 function in the z position. A 5% solution of lysine has a pH close to 10.

La réactivité de la sus-dite fonction amine permet d'obtenir des "associations" (ou complexes) avec les acides mais non des sels classiques avec élimination d'eau : tel est le cas de la lysine et de l'acide aspartique qui forme une combinaison comme les chlorhydrates d'acides aminés.The reactivity of the above-mentioned amine function makes it possible to obtain "associations" (or complexes) with acids but not conventional salts with elimination of water: this is the case of lysine and of aspartic acid which forms a combination like amino acid hydrochlorides.

L'aspartate de lysine correspond à la structure suivante

Figure img00030001
Lysine aspartate corresponds to the following structure
Figure img00030001

Des compositions capillaires avantageuses de l'invention sont telles que la substance active contient l'un au moins des complexes définis ci-dessus à raison d'environ 1% à environ 10%, notamment environ 2% à environ 5% en poids, par rapport au poids total de la composition.Advantageous hair compositions of the invention are such that the active substance contains at least one of the complexes defined above in an amount of from approximately 1% to approximately 10%, in particular approximately 2% to approximately 5% by weight, per relative to the total weight of the composition.

Selon un mode de réalisation avantageux, les compositions capillaires de l'invention sont telles que la substance active est de l'aspartate de lysine à raison d'environ 1 à environ 5% en poids par rapport au poids total de la composition.According to an advantageous embodiment, the hair compositions of the invention are such that the active substance is lysine aspartate in an amount of from 1 to about 5% by weight relative to the total weight of the composition.

Selon un autre mode de réalisation avantageux de l'invention, la substance active est de l'aspartate de lysine en quantité supérieure à 5% jusqu'à une quantité d'environ 10% en poids par rapport au poids total de la composition.According to another advantageous embodiment of the invention, the active substance is lysine aspartate in an amount greater than 5% up to an amount of approximately 10% by weight relative to the total weight of the composition.

Selon un autre mode de réalisation de l'invention, lorsque la substance active est de l'aspartate d'arginine, celui-ci est présent à raison d'au moins 1% à environ 3% en poids par rapport au poids total de la composition.According to another embodiment of the invention, when the active substance is arginine aspartate, this is present in an amount of at least 1% to about 3% by weight relative to the total weight of the composition.

L'aspartate d'arginine est avantageusement présent en quantité supérieure à 3% jusqu'à une quantité d'environ 10% en poids par rapport au poids total de la composition.The arginine aspartate is advantageously present in an amount greater than 3% up to an amount of approximately 10% by weight relative to the total weight of the composition.

Selon un autre mode de réalisation de l'invention, les compositions capillaires contiennent comme substance active du glutamate d'arginine ou du glutamate de lysine à raison d'environ 1% à environ 10% avantageusement d'environ 2% à environ 5% en poids par rapport au poids total de la composition. According to another embodiment of the invention, the hair compositions contain as active substance arginine glutamate or lysine glutamate in an amount of about 1% to about 10% advantageously from about 2% to about 5% in weight relative to the total weight of the composition.

L'aspartate de lysine est disponible commercialement ou peut être obtenu par mise en solution, de préférence aqueuse ou hydroalcoolique, de lysine et d'acide aspartique en quantités appropriées. L'aspartate de lysine peut également être obtenu par mélange de quantités appropriées de lysine et d'acide aspartique, la lysine et/ou l'acide aspartique étant préalablement mis en solution, de préférence aqueuse ou hydroalcoolique.Lysine aspartate is commercially available or can be obtained by dissolving, preferably aqueous or hydroalcoholic, lysine and aspartic acid in appropriate amounts. Lysine aspartate can also be obtained by mixing appropriate amounts of lysine and aspartic acid, the lysine and / or aspartic acid being previously dissolved, preferably aqueous or hydroalcoholic.

L'aspartate d'arginine, le glutamate de lysine et le glutamate d'arginine peuvent être préparés comme il est indiqué à propos de l'aspartate de lysine.Arginine aspartate, lysine glutamate and arginine glutamate can be prepared as directed for lysine aspartate.

Les compositions capillaires de l'invention peuvent être sous forme de liquide, d'émulsion ou de gel, les excipients correspondants étant ceux susceptibles d'être utilisés en cosmétologie.The hair compositions of the invention may be in the form of a liquid, emulsion or gel, the corresponding excipients being those capable of being used in cosmetology.

Les compositions capillaires de l'invention peuvent être obtenues par mélange d'au moins un complexe résultant de l'association, en solution aqueuse ou hydroalcoolique, entre un acide aminé dicarboxylique et un acide aminé basique avec un excipient cosmétologique approprié.The hair compositions of the invention can be obtained by mixing at least one complex resulting from the association, in aqueous or hydroalcoholic solution, between a dicarboxylic amino acid and a basic amino acid with an appropriate cosmetic excipient.

L'invention concerne également une méthode de traitement cosmétique du cuir chevelu, par applications d'une composition capillaire de l'invention sur le cuir chevelu.The invention also relates to a cosmetic treatment method for the scalp, by applying a hair composition of the invention to the scalp.

L'invention concerne également un procédé de neutralisation de l'acide lactique secrété par les glandes eccrines du cuir chevelu, par application d'une composition capillaire de l'invention.The invention also relates to a method for neutralizing the lactic acid secreted by the eccrine glands of the scalp, by applying a hair composition of the invention.

A titre d'exemples non limitatifs de compositions capillaires destinées à combattre les effets agressifs de l'acide lactique niveau du cuir chevelu, citons 1. Aspartate de lysine 2
Alcool éthylique 30
Eau 68
Parfum...qs 2. Aspartate d'arginine 3
Alcool éthylique 30
Eau 67
Parfum...qs 3. Aspartate de lysine 2
Alcool céthylique polyoxy éthylène 5
Eau 93
Parfum...qs
Les chiffres correspondent à des pourcentages en poids par rapport au poids total de la composition.As nonlimiting examples of hair compositions intended to combat the aggressive effects of lactic acid on the scalp, let us mention 1. Lysine aspartate 2
Ethyl alcohol 30
Water 68
Perfume ... qs 2. Arginine aspartate 3
Ethyl alcohol 30
Water 67
Perfume ... qs 3. Lysine Aspartate 2
Polyoxy ethylene ethyl alcohol 5
Water 93
Perfume ... qs
The figures correspond to percentages by weight relative to the total weight of the composition.

L'application sur le cuir chevelu d'une composition capillaire de l'invention, notamment celles contenant comme substance active le complexe acide aspartique-lysine, présente trois avantages - de transformer l'acide lactique de la sueur eccrine en lactate de lysine dénué d'effets agressifs pour le bulbe pileux, et de ce fait, de ne pas réduire la glycolyse qui fournit l'énergie nécessaire à la reproduction des membranes cellulaires; - d'améliorer la teneur en eau des productions kératiniques, les lactates étant des agents d'hydratation; - de libérer de l'acide aspartique, l'action énergétique de cet aminoacide ayant été largement décrit.The application to the scalp of a hair composition of the invention, in particular those containing as active substance the aspartic acid-lysine complex, has three advantages - to transform the lactic acid of eccrine sweat into lysine lactate devoid of 'aggressive effects on the hair bulb, and therefore not to reduce glycolysis which provides the energy necessary for the reproduction of cell membranes; - to improve the water content of keratinous products, lactates being hydrating agents; - to release aspartic acid, the energetic action of this amino acid having been widely described.

Les examens chromatographiques et microscopiques ont montré:
la présence d'acide lactique dans le flux sudoral du cuir chevelu,
la disparition de l'acide lactique, par application d'une solution d'aspartate de lysine, avec l'apparition caractéristique, au microscope en lumière polarisée, de cristaux d'acide aspartique. Chromatographic and microscopic examinations have shown:
the presence of lactic acid in the sweat flow of the scalp,
the disappearance of lactic acid, by application of a solution of lysine aspartate, with the characteristic appearance, under the microscope in polarized light, of crystals of aspartic acid.

Claims (13)

REVENDICATIONS 1. Composition capillaire caractérisée en ce qu'elle contient une substance active contenant au moins un complexe résultant de l'association, en solution aqueuse ou hydroalcoolique, d'un acide aminé dicarboxylique et d'un acide aminé basique.1. Hair composition characterized in that it contains an active substance containing at least one complex resulting from the association, in aqueous or hydroalcoholic solution, of a dicarboxylic amino acid and a basic amino acid. 2. Composition capillaire selon la revendication 1 caractérisée en ce que la substance active est constituée par ou contient l'un au moins des composés suivants2. Hair composition according to claim 1 characterized in that the active substance consists of or contains at least one of the following compounds - aspartate de lysine - lysine aspartate - aspartate d'arginine - arginine aspartate - glutamate de lysine - lysine glutamate - glutamate d'arginine - arginine glutamate 3. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce qu'elle contient comme substance active un complexe selon la revendication 1 ou 2 à raison d'environ 1% à environ 10% notamment d'environ 2% à environ 5% en poids, par rapport au poids total de la composition.3. Hair composition according to one of claims 1 or 2 characterized in that it contains as active substance a complex according to claim 1 or 2 in an amount of about 1% to about 10% in particular from about 2% to about 5% by weight, relative to the total weight of the composition. 4. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce que la substance active est de l'aspartate de lysine à raison d'environ 1% à environ 5% en poids par rapport au poids total de la composition.4. Hair composition according to one of claims 1 or 2 characterized in that the active substance is lysine aspartate in an amount of about 1% to about 5% by weight relative to the total weight of the composition. 5. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce que la substance active est de l'aspartate de lysine en quantité supérieure à 5% jusqu'à une quantité d'environ 10%.5. Hair composition according to one of claims 1 or 2 characterized in that the active substance is lysine aspartate in an amount greater than 5% up to an amount of about 10%. 6. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce que la substance active est de l'aspartate d'arginine à raison d'environ 1% à environ 3% en poids par rapport au poids total de la composition.6. Hair composition according to one of claims 1 or 2 characterized in that the active substance is arginine aspartate in an amount of about 1% to about 3% by weight relative to the total weight of the composition. 7. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce que la substance active est de l'aspartate d'arginine en quantité supérieure à 3% jusqu'à une quantité d'environ 10% en poids par rapport au poids total de la composition.7. Hair composition according to one of claims 1 or 2 characterized in that the active substance is arginine aspartate in an amount greater than 3% up to an amount of about 10% by weight relative to the weight total of the composition. 8. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce que la substance active est de l'aspartate d'arginine en quantité d'environ 1% jusqu'à une quantité inférieure à 3% en poids par rapport au poids total de la composition.8. Hair composition according to one of claims 1 or 2 characterized in that the active substance is arginine aspartate in an amount of about 1% up to an amount less than 3% by weight relative to the weight total of the composition. 9. Composition capillaire selon l'une des revendications 1 ou 2 caractérisée en ce que la substance active est du glutamate d'arginine ou du glutamate de lysine à raison d'environ 1% à environ 10% avantageusement d'environ 2% à environ 5% en poids par rapport au poids total de la composition.9. Hair composition according to one of claims 1 or 2 characterized in that the active substance is arginine glutamate or lysine glutamate in an amount of about 1% to about 10% advantageously from about 2% to about 5% by weight relative to the total weight of the composition. 10. Composition capillaire selon l'une quelconque des revendications 1 à 8, car en ce qu'elle est sous forme de liquide, d'émulsion, de gel.10. Hair composition according to any one of claims 1 to 8, because in that it is in the form of liquid, emulsion, gel. 11. Méthode de traitement cosmétique du cuir chevelu caractérisé par l'application sur le cuir chevelu d'une composition capillaire selon l'une quelconque des revendications 1 à 10 en quantité appropriée.11. A method of cosmetic treatment of the scalp characterized by the application to the scalp of a hair composition according to any one of claims 1 to 10 in an appropriate amount. 12. Procédé de préparation d'une composition capillaire selon l'une des revendications 1 à 10 caractérisée en ce que l'on mélange au moins un complexe résultant de l'association, en solution aqueuse ou hydroalcoolique, entre un acide aminé dicarboxylique et un acide aminé basique avec un excipient cosmétologique approprié.12. Method for preparing a hair composition according to one of claims 1 to 10 characterized in that at least one complex resulting from the association, in aqueous or hydroalcoholic solution, between an amino acid dicarboxylic acid and a basic amino acid with a suitable cosmetic excipient. 13. Procédé de neutralisation de l'acide lactique secrété par les glandes eccrines du cuir chevelu caractérisé en ce qu'il comprend l'application sur le cuir chevelu d'une composition capillaire selon l'une quelconque des revendications 1 à 10. 13. Method for neutralizing the lactic acid secreted by the eccrine glands of the scalp, characterized in that it comprises the application to the scalp of a hair composition according to any one of claims 1 to 10.
FR9014229A 1990-11-15 1990-11-15 HAIR COMPOSITIONS, IN PARTICULAR FOR THE NEUTRALIZATION OF LACTIC ACID FROM SCALP AND METHOD OF COSMETIC TREATMENT OF SCALP. Expired - Lifetime FR2669224B1 (en)

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FR9014229A FR2669224B1 (en) 1990-11-15 1990-11-15 HAIR COMPOSITIONS, IN PARTICULAR FOR THE NEUTRALIZATION OF LACTIC ACID FROM SCALP AND METHOD OF COSMETIC TREATMENT OF SCALP.

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FR9014229A FR2669224B1 (en) 1990-11-15 1990-11-15 HAIR COMPOSITIONS, IN PARTICULAR FOR THE NEUTRALIZATION OF LACTIC ACID FROM SCALP AND METHOD OF COSMETIC TREATMENT OF SCALP.

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009750A1 (en) * 1992-10-30 1994-05-11 Unilever Plc Cosmetic composition
WO1997047276A1 (en) * 1996-06-10 1997-12-18 Bio-Scientific Limited The use of l-lysine in the treatment of hair loss

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382068A (en) * 1962-02-13 1964-12-18 Shiseido Co Ltd Preparations for the toilet
FR1553063A (en) * 1967-11-28 1969-01-10
FR2273514A1 (en) * 1974-06-06 1976-01-02 Orlane COSMETIC PRODUCT WITH SOFTENING ACTION ON THE SKIN
EP0204017A1 (en) * 1985-06-05 1986-12-10 Takasago Perfumery Co., Ltd. Deodorant
JPS6447707A (en) * 1987-08-17 1989-02-22 Shiseido Co Ltd Cosmetic
FR2667787A1 (en) * 1990-10-15 1992-04-17 Contier Marcel Hair lotion intended for neutralising the lactic acid of the scalp, containing basic amino acids combined with aspartic and glutamic acids

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382068A (en) * 1962-02-13 1964-12-18 Shiseido Co Ltd Preparations for the toilet
FR1553063A (en) * 1967-11-28 1969-01-10
FR2273514A1 (en) * 1974-06-06 1976-01-02 Orlane COSMETIC PRODUCT WITH SOFTENING ACTION ON THE SKIN
EP0204017A1 (en) * 1985-06-05 1986-12-10 Takasago Perfumery Co., Ltd. Deodorant
JPS6447707A (en) * 1987-08-17 1989-02-22 Shiseido Co Ltd Cosmetic
FR2667787A1 (en) * 1990-10-15 1992-04-17 Contier Marcel Hair lotion intended for neutralising the lactic acid of the scalp, containing basic amino acids combined with aspartic and glutamic acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 93, no. 26, 29 Décembre 1980, Columbus, Ohio, US; abstract no. 245275s, 'novel cleansing composition' page 374 ;colonne 2 ; *
PATENT ABSTRACTS OF JAPAN vol. 13, no. 238 (C-603)(3586) 5 Juin 1989 & JP-A-01 047 707 ( SHISEIDO CO LTD ) 22 Février 1989 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009750A1 (en) * 1992-10-30 1994-05-11 Unilever Plc Cosmetic composition
WO1997047276A1 (en) * 1996-06-10 1997-12-18 Bio-Scientific Limited The use of l-lysine in the treatment of hair loss
US6136860A (en) * 1996-06-10 2000-10-24 Bio-Scientific Limited Use of L-lysine in the treatment of hair loss

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