FR2668367B1 - Medicament implantable a effet prolonge. - Google Patents
Medicament implantable a effet prolonge.Info
- Publication number
- FR2668367B1 FR2668367B1 FR9013424A FR9013424A FR2668367B1 FR 2668367 B1 FR2668367 B1 FR 2668367B1 FR 9013424 A FR9013424 A FR 9013424A FR 9013424 A FR9013424 A FR 9013424A FR 2668367 B1 FR2668367 B1 FR 2668367B1
- Authority
- FR
- France
- Prior art keywords
- tissue
- active substance
- groupings
- prolonged effect
- implantable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000002035 prolonged effect Effects 0.000 title 1
- 239000000463 material Substances 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 2
- 101100283604 Caenorhabditis elegans pigk-1 gene Proteins 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 abstract 1
- 229930182566 Gentamicin Natural products 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000006065 biodegradation reaction Methods 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- 229960002518 gentamicin Drugs 0.000 abstract 1
- 229960000808 netilmicin Drugs 0.000 abstract 1
- ZBGPYVZLYBDXKO-HILBYHGXSA-N netilmycin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@]([C@H](NC)[C@@H](O)CO1)(C)O)NCC)[C@H]1OC(CN)=CC[C@H]1N ZBGPYVZLYBDXKO-HILBYHGXSA-N 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9013424A FR2668367B1 (fr) | 1990-10-26 | 1990-10-26 | Medicament implantable a effet prolonge. |
| JP3518175A JPH07102224B2 (ja) | 1990-10-26 | 1991-10-22 | 生物分解可能の移植可能の材料及びその製造方法 |
| ES92909593T ES2062896T3 (es) | 1990-10-26 | 1991-10-22 | Material implantable biodegradable y procedimiento de fabricacion. |
| AU88784/91A AU635673B2 (en) | 1990-10-26 | 1991-10-22 | Implantable biodegradable material and method for producing same |
| EP92909593A EP0507944B1 (de) | 1990-10-26 | 1991-10-22 | Bioabsorbierbares implantierbares material und verfahren zur herstellung |
| DK92909593.3T DK0507944T3 (da) | 1990-10-26 | 1991-10-22 | Implanterbart, biologisk nedbrydeligt materiale og fremgangsmåde til dets fremstilling |
| AT92909593T ATE112162T1 (de) | 1990-10-26 | 1991-10-22 | Bioabsorbierbares implantierbares material und verfahren zur herstellung. |
| DE69104345T DE69104345T2 (de) | 1990-10-26 | 1991-10-22 | Bioabsorbierbares implantierbares material und verfahren zur herstellung. |
| CA002070803A CA2070803C (fr) | 1990-10-26 | 1991-10-22 | Materiau implantable biodegradable et procede de fabrication |
| PCT/FR1991/000837 WO1992007554A1 (fr) | 1990-10-26 | 1991-10-22 | Materiau implantable biodegradable et procede de fabrication |
| MX9203526A MX9203526A (es) | 1990-10-26 | 1992-06-26 | Material biodegradable implantable y proceso para su produccion. |
| US08/316,062 US5709875A (en) | 1990-10-26 | 1994-09-30 | Implantable biodegradable material and process for its production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9013424A FR2668367B1 (fr) | 1990-10-26 | 1990-10-26 | Medicament implantable a effet prolonge. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2668367A1 FR2668367A1 (fr) | 1992-04-30 |
| FR2668367B1 true FR2668367B1 (fr) | 1994-05-13 |
Family
ID=9401689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9013424A Expired - Fee Related FR2668367B1 (fr) | 1990-10-26 | 1990-10-26 | Medicament implantable a effet prolonge. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0507944B1 (de) |
| JP (1) | JPH07102224B2 (de) |
| AT (1) | ATE112162T1 (de) |
| AU (1) | AU635673B2 (de) |
| CA (1) | CA2070803C (de) |
| DE (1) | DE69104345T2 (de) |
| DK (1) | DK0507944T3 (de) |
| ES (1) | ES2062896T3 (de) |
| FR (1) | FR2668367B1 (de) |
| MX (1) | MX9203526A (de) |
| WO (1) | WO1992007554A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817327A (en) * | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| US5591453A (en) * | 1994-07-27 | 1997-01-07 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| RU2107490C1 (ru) * | 1995-03-21 | 1998-03-27 | Малое предприятие "Интех" | Материал для заполнения дефектов костной ткани |
| DE10114245A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
| DE10114244A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE31025T1 (de) * | 1983-02-03 | 1987-12-15 | Ethicon Inc | Paste zur blutstillung und temporaeren defektueberbrueckung bei knochentrauma. |
| GB8328074D0 (en) * | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compositions |
| FR2570606A1 (fr) * | 1984-09-26 | 1986-03-28 | Landanger Laboratoire | Obturateur notamment de puits femoral ou de fond de cotyle |
| FI81010C (fi) * | 1986-09-05 | 1990-09-10 | Biocon Oy | Stoedstruktur foer bentransplantat. |
| JPH0223967A (ja) * | 1988-07-13 | 1990-01-26 | Mamoru Nagase | リン酸三カルシウムと酸と多糖類と水と水酸アパタイトを混合する事により硬化生成した人工骨 |
| JPH02102165A (ja) * | 1988-10-12 | 1990-04-13 | Asahi Optical Co Ltd | リン酸カルシウム系セラミックスの製造方法 |
-
1990
- 1990-10-26 FR FR9013424A patent/FR2668367B1/fr not_active Expired - Fee Related
-
1991
- 1991-10-22 JP JP3518175A patent/JPH07102224B2/ja not_active Expired - Fee Related
- 1991-10-22 DK DK92909593.3T patent/DK0507944T3/da active
- 1991-10-22 CA CA002070803A patent/CA2070803C/fr not_active Expired - Lifetime
- 1991-10-22 ES ES92909593T patent/ES2062896T3/es not_active Expired - Lifetime
- 1991-10-22 AT AT92909593T patent/ATE112162T1/de not_active IP Right Cessation
- 1991-10-22 WO PCT/FR1991/000837 patent/WO1992007554A1/fr not_active Ceased
- 1991-10-22 DE DE69104345T patent/DE69104345T2/de not_active Expired - Lifetime
- 1991-10-22 AU AU88784/91A patent/AU635673B2/en not_active Expired
- 1991-10-22 EP EP92909593A patent/EP0507944B1/de not_active Expired - Lifetime
-
1992
- 1992-06-26 MX MX9203526A patent/MX9203526A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE112162T1 (de) | 1994-10-15 |
| EP0507944B1 (de) | 1994-09-28 |
| JPH07102224B2 (ja) | 1995-11-08 |
| CA2070803C (fr) | 1997-01-07 |
| FR2668367A1 (fr) | 1992-04-30 |
| AU8878491A (en) | 1992-05-26 |
| MX9203526A (es) | 1992-07-01 |
| ES2062896T3 (es) | 1994-12-16 |
| AU635673B2 (en) | 1993-03-25 |
| DE69104345D1 (de) | 1994-11-03 |
| EP0507944A1 (de) | 1992-10-14 |
| DK0507944T3 (da) | 1995-04-10 |
| CA2070803A1 (fr) | 1992-04-27 |
| JPH04506471A (ja) | 1992-11-12 |
| DE69104345T2 (de) | 1995-05-04 |
| WO1992007554A1 (fr) | 1992-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |