ES2062896T3 - Material implantable biodegradable y procedimiento de fabricacion. - Google Patents

Material implantable biodegradable y procedimiento de fabricacion.

Info

Publication number
ES2062896T3
ES2062896T3 ES92909593T ES92909593T ES2062896T3 ES 2062896 T3 ES2062896 T3 ES 2062896T3 ES 92909593 T ES92909593 T ES 92909593T ES 92909593 T ES92909593 T ES 92909593T ES 2062896 T3 ES2062896 T3 ES 2062896T3
Authority
ES
Spain
Prior art keywords
implantable material
tissue
manufacturing procedure
active substance
groupings
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92909593T
Other languages
English (en)
Inventor
Albert Lebugle
Anne Julia
Fernand Rodriguez
Paul Bonnevialle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of ES2062896T3 publication Critical patent/ES2062896T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MATERIAL IMPLANTABLE BIODEGRADABLE Y PROCESO DE FABRICACION. LA INVENCION SE REFIERE A UN MATERIAL IMPLANTABLE EN UN TEJIDO VIVO, EN PARTICULAR TEJIDO OSEO, QUE TIENE UNA VELOCIDAD DE BIODEGRADACION ADAPTADA A LA VELOCIDAD DE REGENERACION DEL TEJIDO, ESTE MATERIAL PUEDE COMPRENDER UNA SUSTANCIA ACTIVA PARA PRESENTAR UN EFECTO TERAPEUTICO DE DURACION PROLONGADA. ESTE MATERIAL COMPRENDE (A) UN FOSFATO DE CALCIO, DE ESTRUCTURA APATITICA O TRICLINICA QUE CONTIENE GRUPOS HPO4 Y PO4, (B) UN OSIDO O UN POLIOSIDO BIODEGRADABLE, EN PARTICULAR DEXTRANO, (C) SI ES NECESARIO, UNA SUSTANCIA ACTIVA QUE POSEE GRUPOS AMINAS TALES COMO NETILMICINA Y/O GENTAMICINA EN FORMA DE UN SULFATO. EL MATERIAL IMPLANTABLE DE LA INVENCION PUEDE ESTAR FABRICADO EN FRIO COMPACTANDO SUS DIVERSOS CONSTITUYENTES EN ESTADO PULVERULENTO.
ES92909593T 1990-10-26 1991-10-22 Material implantable biodegradable y procedimiento de fabricacion. Expired - Lifetime ES2062896T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9013424A FR2668367B1 (fr) 1990-10-26 1990-10-26 Medicament implantable a effet prolonge.

Publications (1)

Publication Number Publication Date
ES2062896T3 true ES2062896T3 (es) 1994-12-16

Family

ID=9401689

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92909593T Expired - Lifetime ES2062896T3 (es) 1990-10-26 1991-10-22 Material implantable biodegradable y procedimiento de fabricacion.

Country Status (11)

Country Link
EP (1) EP0507944B1 (es)
JP (1) JPH07102224B2 (es)
AT (1) ATE112162T1 (es)
AU (1) AU635673B2 (es)
CA (1) CA2070803C (es)
DE (1) DE69104345T2 (es)
DK (1) DK0507944T3 (es)
ES (1) ES2062896T3 (es)
FR (1) FR2668367B1 (es)
MX (1) MX9203526A (es)
WO (1) WO1992007554A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US5817327A (en) * 1994-07-27 1998-10-06 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
DE10114244A1 (de) 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0115549B1 (de) * 1983-02-03 1987-11-25 Ethicon, Inc. Paste zur Blutstillung und temporären Defektüberbrückung bei Knochentrauma
GB8328074D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compositions
FR2570606A1 (fr) * 1984-09-26 1986-03-28 Landanger Laboratoire Obturateur notamment de puits femoral ou de fond de cotyle
FI81010C (fi) * 1986-09-05 1990-09-10 Biocon Oy Stoedstruktur foer bentransplantat.
JPH0223967A (ja) * 1988-07-13 1990-01-26 Mamoru Nagase リン酸三カルシウムと酸と多糖類と水と水酸アパタイトを混合する事により硬化生成した人工骨
JPH02102165A (ja) * 1988-10-12 1990-04-13 Asahi Optical Co Ltd リン酸カルシウム系セラミックスの製造方法

Also Published As

Publication number Publication date
JPH04506471A (ja) 1992-11-12
EP0507944B1 (fr) 1994-09-28
MX9203526A (es) 1992-07-01
AU635673B2 (en) 1993-03-25
WO1992007554A1 (fr) 1992-05-14
FR2668367B1 (fr) 1994-05-13
CA2070803C (fr) 1997-01-07
DK0507944T3 (da) 1995-04-10
FR2668367A1 (fr) 1992-04-30
EP0507944A1 (fr) 1992-10-14
JPH07102224B2 (ja) 1995-11-08
DE69104345T2 (de) 1995-05-04
CA2070803A1 (fr) 1992-04-27
AU8878491A (en) 1992-05-26
DE69104345D1 (de) 1994-11-03
ATE112162T1 (de) 1994-10-15

Similar Documents

Publication Publication Date Title
ES2184895T3 (es) Sistema no polimerico de administracion con liberacion retardada.
ATE353677T1 (de) Material zur knochenrekonstruktion
CA2158638A1 (en) A Composition and a Method for Tissue Augmentation
ATE279950T1 (de) Zusammensetzung zur implantation in den menschlichen und tierischen körper
AU6739487A (en) Freeze-dried foam
GR3034921T3 (en) Tissue treatment composition comprising fibrin or fibrinogen and biodegradable and biocompatible polymer.
BR9305783A (pt) Processo para preparar grânulos dispersiveis em água e grânulos dispersíveis em água
ES2058411T3 (es) Sustancia fr 901228 y su preparacion.
IS4083A (is) Samsetning lyfjaefna, aðferð til framleiðslu hennar, og notkunar sem lyfja
IL115138A0 (en) Implantable polymer-containing molded articles for the administration of active substances to plants and processes for the preparation thereof
BG100911A (en) Biophosphonic acids-sontaining wet-granulated form
CA2263557A1 (en) Implant consisting of a carrier material containing medical substances and method to produce such an implant
ES2062896T3 (es) Material implantable biodegradable y procedimiento de fabricacion.
GR3034761T3 (en) Methods of enhancing wound healing and tissue repair.
ZA973751B (en) Pesticides comprising benzophenanthridine alkaloids.
DE50105384D1 (de) Zubereitung zur behandlung von flächigen, offenen wunden
CA2223049A1 (en) Terminally sterilized osteogenic devices and preparation thereof
UA23369A (uk) Антисептичний перев`язний матеріал
RU92016566A (ru) Биокерамическая система для ввода биологически активных соединений, способ ее получения, фармацевтическое средство, способ применения биокерамической системы
ES2157432T3 (es) Nuevo material protesico biocompatible, protesis o sistemas protesicos constituidos por dicho material y su procedimiento de preparacion por doble implantacion ionica de calcio y de fosforo.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 507944

Country of ref document: ES