FR2664287A1 - Nouveau polypeptide presentant une activite enzymatique, et gene codant pour ce polypeptide. - Google Patents

Nouveau polypeptide presentant une activite enzymatique, et gene codant pour ce polypeptide. Download PDF

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Publication number
FR2664287A1
FR2664287A1 FR9008416A FR9008416A FR2664287A1 FR 2664287 A1 FR2664287 A1 FR 2664287A1 FR 9008416 A FR9008416 A FR 9008416A FR 9008416 A FR9008416 A FR 9008416A FR 2664287 A1 FR2664287 A1 FR 2664287A1
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FR
France
Prior art keywords
sequence
nucleotide
constituted
polypeptide
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9008416A
Other languages
English (en)
French (fr)
Other versions
FR2664287B1 (ja
Inventor
Llorens-Cortes Catherine
Giros Brunopollard Helene
Schwartz Jean-Charles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to FR9008416A priority Critical patent/FR2664287A1/fr
Publication of FR2664287A1 publication Critical patent/FR2664287A1/fr
Application granted granted Critical
Publication of FR2664287B1 publication Critical patent/FR2664287B1/fr
Granted legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6494—Neprilysin (3.4.24.11), i.e. enkephalinase or neutral-endopeptidase 24.11
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24011—Neprilysin (3.4.24.11), i.e. enkephalinase or neutral endopeptidase 24.11
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FR9008416A 1990-07-03 1990-07-03 Nouveau polypeptide presentant une activite enzymatique, et gene codant pour ce polypeptide. Granted FR2664287A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9008416A FR2664287A1 (fr) 1990-07-03 1990-07-03 Nouveau polypeptide presentant une activite enzymatique, et gene codant pour ce polypeptide.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9008416A FR2664287A1 (fr) 1990-07-03 1990-07-03 Nouveau polypeptide presentant une activite enzymatique, et gene codant pour ce polypeptide.

Publications (2)

Publication Number Publication Date
FR2664287A1 true FR2664287A1 (fr) 1992-01-10
FR2664287B1 FR2664287B1 (ja) 1994-08-19

Family

ID=9398295

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9008416A Granted FR2664287A1 (fr) 1990-07-03 1990-07-03 Nouveau polypeptide presentant une activite enzymatique, et gene codant pour ce polypeptide.

Country Status (1)

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FR (1) FR2664287A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046403A1 (fr) * 1998-03-11 1999-09-16 Exonhit Therapeutics S.A. Criblage differentiel qualitatif
US6881571B1 (en) 1998-03-11 2005-04-19 Exonhit Therapeutics S.A. Qualitative differential screening

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0272928A2 (en) * 1986-12-24 1988-06-29 Genentech, Inc. Compositions and methods for the synthesis and assay of enkephalinase
WO1989005353A1 (en) * 1987-12-04 1989-06-15 Dana Farber Cancer Institute Common acute lymphoblastic leukemia antigen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0272928A2 (en) * 1986-12-24 1988-06-29 Genentech, Inc. Compositions and methods for the synthesis and assay of enkephalinase
WO1989005353A1 (en) * 1987-12-04 1989-06-15 Dana Farber Cancer Institute Common acute lymphoblastic leukemia antigen

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. vol. 144, no. 1, 14 avril 1987, DULUTH, MINNESOTA US pages 59 - 66; MALFROY B. et al: "Molecular cloning and amino acid sequence of rat enkepalinase." *
CHEMICAL ABSTRACTS, vol. 105, no. 11, 15 septembre 1986 Columbus, Ohio, USA J.M.LECOMTE et al: "Pharmalogical properties of acetorphan ,a parenterally active "enkephalinase inhibitor" ." page 54; colonne de droite; ref. no. 91131U *
European Journal of pharmacology vol. 133, 1987, AMSTERDAM pages 155 - 164; Pollard H. et al: "Characterization of 2 probes for the localization of enkephalinase in ratbrain Ý3H¨thiorphan and 125I-labeled mab" *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA. vol. 86, septembre 1989, WASHINGTON US pages 7103 - 7107; D'ADAMIO L. et al: "Organization of the gene encoding CALLA(neutral endopeptidase 24.11):Multiple miniexons and separate 5'untranslated regions" *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046403A1 (fr) * 1998-03-11 1999-09-16 Exonhit Therapeutics S.A. Criblage differentiel qualitatif
FR2775984A1 (fr) * 1998-03-11 1999-09-17 Bioscreen Therapeutics Sa Criblage differentiel qualitatif
US6251590B1 (en) 1998-03-11 2001-06-26 Exonhit Therapeutics S.A. Differential Qualitative screening
US6881571B1 (en) 1998-03-11 2005-04-19 Exonhit Therapeutics S.A. Qualitative differential screening
EP1566453A2 (fr) * 1998-03-11 2005-08-24 Exonhit Therapeutics S.A. Criblage différentiel qualitatif
EP1566453A3 (fr) * 1998-03-11 2009-11-18 Exonhit Therapeutics S.A. Criblage différentiel qualitatif
US8003375B2 (en) 1998-03-11 2011-08-23 Exonhit Therapeutics S.A. Qualitative differential screening

Also Published As

Publication number Publication date
FR2664287B1 (ja) 1994-08-19

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