FR2587119B1 - Appareil optique servant a effectuer des analyses - Google Patents

Appareil optique servant a effectuer des analyses

Info

Publication number
FR2587119B1
FR2587119B1 FR868612550A FR8612550A FR2587119B1 FR 2587119 B1 FR2587119 B1 FR 2587119B1 FR 868612550 A FR868612550 A FR 868612550A FR 8612550 A FR8612550 A FR 8612550A FR 2587119 B1 FR2587119 B1 FR 2587119B1
Authority
FR
France
Prior art keywords
optical apparatus
performing analyzes
analyzes
optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR868612550A
Other languages
English (en)
Other versions
FR2587119A1 (fr
Inventor
Thomas R Glass
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ord Inc
Original Assignee
Ord Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ord Inc filed Critical Ord Inc
Publication of FR2587119A1 publication Critical patent/FR2587119A1/fr
Application granted granted Critical
Publication of FR2587119B1 publication Critical patent/FR2587119B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
FR868612550A 1985-09-09 1986-09-08 Appareil optique servant a effectuer des analyses Expired - Fee Related FR2587119B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/773,938 US4844869A (en) 1985-09-09 1985-09-09 Immunoassay apparatus

Publications (2)

Publication Number Publication Date
FR2587119A1 FR2587119A1 (fr) 1987-03-13
FR2587119B1 true FR2587119B1 (fr) 1991-11-29

Family

ID=25099767

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868612550A Expired - Fee Related FR2587119B1 (fr) 1985-09-09 1986-09-08 Appareil optique servant a effectuer des analyses

Country Status (6)

Country Link
US (1) US4844869A (fr)
JP (1) JPS6279333A (fr)
CA (1) CA1271050A (fr)
DE (1) DE3630353A1 (fr)
FR (1) FR2587119B1 (fr)
GB (1) GB2182141B (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4909990A (en) * 1987-09-02 1990-03-20 Myron J. Block Immunoassay apparatus
US5152962A (en) * 1988-07-22 1992-10-06 Ord Corp. Immunoassay apparatus
US5106751A (en) * 1988-09-15 1992-04-21 Biotronic Systems Corporation Apparatus for supporting a biochemical sensor responsive to bubbles
US5268304A (en) * 1988-10-13 1993-12-07 The United States Of America As Represented By The Secretary Of The Navy Method of determining the concentration of a chemical of interest in a solution
US5401469A (en) * 1989-04-19 1995-03-28 Ibiden Co., Ltd. Plastic optical biomaterials assay device
WO1990013029A1 (fr) * 1989-04-19 1990-11-01 Ibiden Co., Ltd. Reactif de dosage de substances biologiquement actives, son procede de production, procede et appareil de dosage
US6010867A (en) * 1989-04-19 2000-01-04 Ibiden Co., Ltd. Reagent for biomaterials assay, preparation method thereof, and assay method
JP2612641B2 (ja) * 1989-06-22 1997-05-21 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ ベノートスハップ 光学的分析方法、そこで使用するための装置、及びアッセイ方法
US5192510A (en) * 1991-01-30 1993-03-09 E. I. Du Pont De Nemours And Company Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence
US5376551A (en) * 1991-03-12 1994-12-27 University Of Utah Research Foundation Apparatus for using fluorescently labeled ligands in studying interaction of a native ligand and its receptor
US5262638A (en) * 1991-09-16 1993-11-16 The United States Of America As Represented By The United States National Aeronautics And Space Administration Optical fibers and fluorosensors having improved power efficiency and methods of producing same
EP1130116A3 (fr) * 1992-04-06 2004-01-14 Abbott Laboratories Méthode et apparatus pour la détéction des acides nucléiques acide utilisant la réfléctance interne totale
US5354574A (en) * 1992-06-23 1994-10-11 Ibiden Co., Ltd. Method for producing optical fiber having formyl groups on core surface thereof
US5334349A (en) * 1992-07-16 1994-08-02 Schiapparelli Biosystems, Inc. Liquid transfer module for a chemical analyzer
US5637467A (en) * 1992-10-13 1997-06-10 Behringwerke Ag Heterogeneous assay using a pendulous drop
US5496700A (en) * 1993-08-06 1996-03-05 The United States Of America As Represented By The Secretary Of The Navy Optical immunoassay for microbial analytes using non-specific dyes
US5624850A (en) * 1994-06-06 1997-04-29 Idetek, Inc. Immunoassays in capillaries
US5492674A (en) * 1995-03-17 1996-02-20 Boehringer Mannheim Corporation Evanescent wave immunoassay system
US5739537A (en) * 1995-12-21 1998-04-14 Perstorp Analytical, Inc. NIR absorbance measuring instrument with ATR probe
IL116972A0 (en) * 1996-01-31 1996-05-14 Israel Atomic Energy Comm Optical flow cell for use in spectral analysis
US5854863A (en) * 1996-03-15 1998-12-29 Erb; Judith Surface treatment and light injection method and apparatus
US6008055A (en) * 1998-06-30 1999-12-28 Transgenomic, Inc. Modular component fiber optic fluorescence detector system, and method of use
FR2752055B1 (fr) * 1996-08-02 1998-09-11 Commissariat Energie Atomique Capteur tubulaire a onde evanescente pour spectroscopie d'absorption moleculaire
DE19651935A1 (de) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Detektionssystem für den optischen Nachweis von Molekülen
US6136611A (en) * 1997-07-31 2000-10-24 Research International, Inc. Assay methods and apparatus
DE19742227A1 (de) * 1997-09-25 1999-04-01 Juergen Prof Dipl Phys Wolfrum Verfahren zum Sequenzieren eines einzelnen DNA-Moleküls
AU1524500A (en) 1998-11-13 2000-06-05 Leica Microsystems Inc. Refractometer and method for qualitative and quantitative measurements
JP3429282B2 (ja) * 2001-02-02 2003-07-22 リサーチ・インターナショナル・インコーポレーテッド 自動化されたシステム、及びサンプルの分析方法
US7157047B2 (en) * 2001-02-09 2007-01-02 Pss Bio Instruments, Inc. Device for containing, reacting and measuring, and method of containing, reacting and measuring
US8211657B2 (en) * 2002-04-29 2012-07-03 The Board Of Trustees Of The University Of Arkansas Capillary-column-based bioseparator/bioreactor with an optical/electrochemical detector for detection of microbial pathogens
US7095502B2 (en) * 2002-08-06 2006-08-22 Joseph Lakowicz Optical structures for metal-enhanced sensing
US7289207B2 (en) 2003-10-28 2007-10-30 Los Alamos National Security, Llc Integrated optical biosensor system (IOBS)
US20050282182A1 (en) * 2003-12-30 2005-12-22 Universal Bio Research Co., Ltd. Reaction vessel and reaction apparatus comprising three-dimensional particle array
US7496245B2 (en) * 2004-08-20 2009-02-24 Research International, Inc. Misalignment compensating optical sensor and method
WO2007102783A1 (fr) * 2006-03-07 2007-09-13 Nanyang Technological University Dispositif de dosage immunologique microfluidique
US7651869B2 (en) * 2006-03-14 2010-01-26 Research International, Inc. Optical assay apparatus and methods
US20110143378A1 (en) * 2009-11-12 2011-06-16 CyVek LLC. Microfluidic method and apparatus for high performance biological assays
CN102713621B (zh) 2009-11-23 2016-10-19 西维克公司 用于施行化验的方法和设备
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9651568B2 (en) 2009-11-23 2017-05-16 Cyvek, Inc. Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
CN106552682B (zh) 2011-03-22 2020-06-19 西维克公司 微流体装置以及制造方法和用途
EP2822689B1 (fr) 2012-03-08 2023-07-26 Cyvek, Inc. Particules micro-tubulaires pour analyses microfluidiques et procédés de fabrication
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399099A (en) * 1979-09-20 1983-08-16 Buckles Richard G Optical fiber apparatus for quantitative analysis
EP0061884A1 (fr) * 1981-03-30 1982-10-06 Imperial Chemical Industries Plc Capteur en fibre optique
JPS58159501U (ja) * 1982-04-19 1983-10-24 旭光学工業株式会社 伝送用フアイバ−のトラブル検出安全装置
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
US4558014A (en) * 1983-06-13 1985-12-10 Myron J. Block Assay apparatus and methods
US4671938A (en) * 1985-09-09 1987-06-09 Ciba-Corning Diagnostics, Corp. Immunoassay apparatus

Also Published As

Publication number Publication date
DE3630353A1 (de) 1987-03-19
GB2182141B (en) 1989-12-28
US4844869A (en) 1989-07-04
JPS6279333A (ja) 1987-04-11
GB2182141A (en) 1987-05-07
GB8620797D0 (en) 1986-10-08
FR2587119A1 (fr) 1987-03-13
CA1271050A (fr) 1990-07-03

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Legal Events

Date Code Title Description
ST Notification of lapse