FR2577931B1 - Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique - Google Patents

Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique

Info

Publication number
FR2577931B1
FR2577931B1 FR8502763A FR8502763A FR2577931B1 FR 2577931 B1 FR2577931 B1 FR 2577931B1 FR 8502763 A FR8502763 A FR 8502763A FR 8502763 A FR8502763 A FR 8502763A FR 2577931 B1 FR2577931 B1 FR 2577931B1
Authority
FR
France
Prior art keywords
renin
preparation
therapeutic application
acid protein
protein inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8502763A
Other languages
English (en)
Other versions
FR2577931A1 (fr
Inventor
Jean Wagnon
Remy Guegan
Colette Lacour
Dino Nisato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8502763A priority Critical patent/FR2577931B1/fr
Priority to PT82077A priority patent/PT82077B/fr
Priority to EP86901417A priority patent/EP0214209A1/fr
Priority to NZ215282A priority patent/NZ215282A/xx
Priority to GR860532A priority patent/GR860532B/el
Priority to JP61501336A priority patent/JPS62502401A/ja
Priority to PCT/FR1986/000060 priority patent/WO1986004901A1/fr
Priority to ZA861439A priority patent/ZA861439B/xx
Priority to ES552407A priority patent/ES8900018A1/es
Priority to AU54100/86A priority patent/AU587426B2/en
Priority to DK89286A priority patent/DK89286A/da
Priority to KR1019860001351A priority patent/KR860006487A/ko
Publication of FR2577931A1 publication Critical patent/FR2577931A1/fr
Application granted granted Critical
Publication of FR2577931B1 publication Critical patent/FR2577931B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR8502763A 1985-02-26 1985-02-26 Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique Expired FR2577931B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8502763A FR2577931B1 (fr) 1985-02-26 1985-02-26 Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique
PT82077A PT82077B (fr) 1985-02-26 1986-02-24 Procede pour l'obtention des derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides
NZ215282A NZ215282A (en) 1985-02-26 1986-02-25 Peptide amino alcohol, renin and acid protease inhibitors, preparation and pharmaceutical composition
GR860532A GR860532B (en) 1985-02-26 1986-02-25 Process for obtainig peptidic derivtives of renine aminoalcohols inhibitor and acid proteases
JP61501336A JPS62502401A (ja) 1985-02-26 1986-02-25 レニンおよび酸性プロテア−ゼ阻害ペプチドアミノアルコ−ル誘導体，その製造方法および治療への応用
PCT/FR1986/000060 WO1986004901A1 (fr) 1985-02-26 1986-02-25 Derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation, et leur application en therapeutique
EP86901417A EP0214209A1 (fr) 1985-02-26 1986-02-25 Derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation, et leur application en therapeutique
ES552407A ES8900018A1 (es) 1985-02-26 1986-02-26 Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas
ZA861439A ZA861439B (en) 1985-02-26 1986-02-26 Peptide amino-alcohol derivatives inhibiting renin and acid proteases,process for preparation and application in therapy
AU54100/86A AU587426B2 (en) 1985-02-26 1986-02-26 Peptide amino-alcohol derivatives inhibiting renin and acid proteases, process for preparation and application in therapy
DK89286A DK89286A (da) 1985-02-26 1986-02-26 Renininhiberende peptid-aminoalkoholderivater, som ogsaa inhiberer sure proteaser, fremgangsmaade til fremstilling deraf og derivaternes terapeutiske anvendelse
KR1019860001351A KR860006487A (ko) 1985-02-26 1986-02-26 레닌 및 산 프로테아제를 억제하는 펩티드 아미노-알코올 유도체의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8502763A FR2577931B1 (fr) 1985-02-26 1985-02-26 Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2577931A1 FR2577931A1 (fr) 1986-08-29
FR2577931B1 true FR2577931B1 (fr) 1987-03-20

Family

ID=9316632

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8502763A Expired FR2577931B1 (fr) 1985-02-26 1985-02-26 Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique

Country Status (3)

Country Link
JP (1) JPS62502401A (fr)
FR (1) FR2577931B1 (fr)
ZA (1) ZA861439B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2646354B1 (fr) * 1989-04-27 1994-06-10 Sanofi Sa Utilisation de peptides inhibiteurs de proteases acides pour la preparation de medicaments utiles pour le traitement de maladies virales
KR101641281B1 (ko) 2016-01-13 2016-07-21 한전원자력연료 주식회사 알루미나 시멘트를 포함하는 방사성폐기물 고화용 고화제 조성물 및 이를 이용한 방사성폐기물의 고화방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114993B1 (fr) * 1982-12-27 1990-05-16 Merck & Co. Inc. Tripeptides, inhibiteurs de rénine

Also Published As

Publication number Publication date
ZA861439B (en) 1986-10-29
FR2577931A1 (fr) 1986-08-29
JPS62502401A (ja) 1987-09-17

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Legal Events

Date Code Title Description
ST Notification of lapse