FR2557977B1 - Appareil pour eliminer une interference de bruit de fond dans des mesures de fluorescence - Google Patents

Appareil pour eliminer une interference de bruit de fond dans des mesures de fluorescence

Info

Publication number
FR2557977B1
FR2557977B1 FR8500090A FR8500090A FR2557977B1 FR 2557977 B1 FR2557977 B1 FR 2557977B1 FR 8500090 A FR8500090 A FR 8500090A FR 8500090 A FR8500090 A FR 8500090A FR 2557977 B1 FR2557977 B1 FR 2557977B1
Authority
FR
France
Prior art keywords
background noise
noise interference
fluorescence measurements
eliminating background
eliminating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8500090A
Other languages
English (en)
Other versions
FR2557977A1 (fr
Inventor
John Calvin Martin
James Hubert Jett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Energy
Original Assignee
US Department of Energy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Energy filed Critical US Department of Energy
Publication of FR2557977A1 publication Critical patent/FR2557977A1/fr
Application granted granted Critical
Publication of FR2557977B1 publication Critical patent/FR2557977B1/fr
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1438Using two lasers in succession
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
FR8500090A 1984-01-06 1985-01-04 Appareil pour eliminer une interference de bruit de fond dans des mesures de fluorescence Expired FR2557977B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/568,768 US4573796A (en) 1984-01-06 1984-01-06 Apparatus for eliminating background interference in fluorescence measurements

Publications (2)

Publication Number Publication Date
FR2557977A1 FR2557977A1 (fr) 1985-07-12
FR2557977B1 true FR2557977B1 (fr) 1988-05-27

Family

ID=24272653

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8500090A Expired FR2557977B1 (fr) 1984-01-06 1985-01-04 Appareil pour eliminer une interference de bruit de fond dans des mesures de fluorescence

Country Status (6)

Country Link
US (1) US4573796A (fr)
JP (1) JPS60209147A (fr)
CA (1) CA1222394A (fr)
DE (1) DE3500247A1 (fr)
FR (1) FR2557977B1 (fr)
GB (1) GB2153521B (fr)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689304A (en) * 1984-10-19 1987-08-25 Abbott Laboratories Air/liquid detection device for blood sample analysis
JPS62123830A (ja) * 1985-11-25 1987-06-05 Sharp Corp ロ−タリ−エンコ−ダ
JPS62126326A (ja) * 1985-11-26 1987-06-08 Rion Co Ltd 粒子計測方法
US4791310A (en) * 1986-10-02 1988-12-13 Syracuse University Fluorescence microscopy
US4804853A (en) * 1987-04-23 1989-02-14 High Yield Technology Compact particle flux monitor
JP2642632B2 (ja) * 1987-07-03 1997-08-20 株式会社日立製作所 微粒子計測装置および微粒子計測方法
US4987539A (en) * 1987-08-05 1991-01-22 Stanford University Apparatus and method for multidimensional characterization of objects in real time
US4837446A (en) * 1988-03-31 1989-06-06 International Paper Company Apparatus and process for testing uniformity of pulp
US5760900A (en) * 1989-03-18 1998-06-02 Canon Kabushiki Kaisha Method and apparatus for optically measuring specimen
US4979824A (en) * 1989-05-26 1990-12-25 Board Of Trustees Of The Leland Stanford Junior University High sensitivity fluorescent single particle and single molecule detection apparatus and method
NO894680L (no) * 1989-11-24 1991-05-27 Flowtech A S V Harald Steen Pulsmodulasjon av eksitasjonslyskilden i vaeskestroemcytofotometere.
DE69028687T2 (de) * 1989-12-15 1997-04-10 Canon Kk Vorrichtung zur optischen Messung einer Probe
DE69118429T2 (de) * 1990-01-26 1996-09-12 Canon Kk Verfahren zur Messung einer Spezies unter Verwendung von Fluoreszenzlicht
GB9015793D0 (en) * 1990-07-18 1990-09-05 Medical Res Council Confocal scanning optical microscope
US5110204A (en) * 1990-11-06 1992-05-05 Trustees Of Princeton University Velocity measurement by the vibrational tagging of diatomic molecules
JP3084296B2 (ja) * 1991-02-27 2000-09-04 シスメックス株式会社 フローイメージサイトメータ
JP3121849B2 (ja) * 1991-02-27 2001-01-09 シスメックス株式会社 フローイメージサイトメータ
JPH0734012B2 (ja) * 1991-02-27 1995-04-12 東亜医用電子株式会社 フローイメージサイトメータ
US5999256A (en) * 1992-02-12 1999-12-07 Cambridge Consultants Limited Particle measurement system
GB9202887D0 (en) * 1992-02-12 1992-03-25 Cambridge Consultants A particle sizing system based on incoherent structured illumination
US5461236A (en) * 1992-06-09 1995-10-24 Herbert R. Gram Oil spill detection system
US5270548A (en) * 1992-07-31 1993-12-14 The United States Of America As Represented By The United States Department Of Energy Phase-sensitive flow cytometer
US5355215A (en) * 1992-09-30 1994-10-11 Environmental Research Institute Of Michigan Method and apparatus for quantitative fluorescence measurements
US5483469A (en) * 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
US5489977A (en) * 1993-08-11 1996-02-06 Texaco Inc. Photomeric means for monitoring solids and fluorescent material in waste water using a falling stream water sampler
JP2529661B2 (ja) * 1993-08-20 1996-08-28 アネルバ株式会社 粒子検出装置
JP2835692B2 (ja) * 1994-03-10 1998-12-14 東亜医用電子 株式会社 流体中の粒子分析装置
US6800452B1 (en) 1994-08-08 2004-10-05 Science Applications International Corporation Automated methods for simultaneously performing a plurality of signal-based assays
US5528045A (en) * 1995-04-06 1996-06-18 Becton Dickinson And Company Particle analyzer with spatially split wavelength filter
US5682038A (en) * 1995-04-06 1997-10-28 Becton Dickinson And Company Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations
US5909278A (en) * 1996-07-29 1999-06-01 The Regents Of The University Of California Time-resolved fluorescence decay measurements for flowing particles
US5827660A (en) * 1996-08-09 1998-10-27 University Of Massachusetts Caged fluorochrome-labeled probes and subtraction of autoflourescence background
CA2279574C (fr) 1997-01-31 2007-07-24 The Horticulture & Food Research Institute Of New Zealand Ltd. Appareil optique
US6049380A (en) * 1997-11-12 2000-04-11 Regents Of The University Of California Single molecule identification using selected fluorescence characteristics
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6320196B1 (en) 1999-01-28 2001-11-20 Agilent Technologies, Inc. Multichannel high dynamic range scanner
US6628385B1 (en) 1999-02-05 2003-09-30 Axon Instruments, Inc. High efficiency, large field scanning microscope
FR2792725B1 (fr) * 1999-04-23 2001-12-07 Junior Instruments Procede et dispositif pour la detection de variations de proprietes optiques d'un echantillon liquide dans un processus d'analyse
US6927065B2 (en) * 1999-08-13 2005-08-09 U.S. Genomics, Inc. Methods and apparatus for characterization of single polymers
US6813017B1 (en) 1999-10-20 2004-11-02 Becton, Dickinson And Company Apparatus and method employing incoherent light emitting semiconductor devices as particle detection light sources in a flow cytometer
US7208265B1 (en) * 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
WO2001085913A2 (fr) 2000-05-09 2001-11-15 Xy, Inc. Populations de spermatozoides tres purs, porteurs de chromosomes x et y
US6549275B1 (en) * 2000-08-02 2003-04-15 Honeywell International Inc. Optical detection system for flow cytometry
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US7277166B2 (en) 2000-08-02 2007-10-02 Honeywell International Inc. Cytometer analysis cartridge optical configuration
US20040031071A1 (en) * 2000-10-05 2004-02-12 Xy, Inc. System of hysteroscopic insemination of mares
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
CA2468772C (fr) 2000-11-29 2013-10-29 George E. Seidel Systeme de dissociation de spermatozoides congeles-decongeles porteurs d'un chromosome x de ceux porteurs d'un chromosome y
JP4057422B2 (ja) * 2001-01-25 2008-03-05 プレシジョン・システム・サイエンス株式会社 微小物識別装置およびその識別方法
US6870165B2 (en) * 2001-10-19 2005-03-22 Biocal Technology, Inc. Multi-color multiplexed analysis in a bio-separation system
MXPA05000865A (es) * 2002-07-22 2005-04-28 Xy Inc Sistema para el proceso de celulas espermaticas.
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
EP1545203B1 (fr) * 2002-08-01 2016-10-19 Xy, Llc Systeme de separation de cellules spermatiques basse pression
FI112504B (fi) * 2002-08-07 2003-12-15 Cyflo Oy Menetelmä bakteerien tunnistamiseksi
AU2003265471B2 (en) * 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US6936828B2 (en) * 2003-02-14 2005-08-30 Honeywell International Inc. Particle detection system and method
DK2305171T3 (da) 2003-03-28 2022-03-21 Inguran Llc Apparat og fremgangsmåder til tilvejebringelse af kønssorteret dyresæd
DK1625203T3 (en) * 2003-05-15 2015-07-06 Xy Llc EFFECTIVE SEPARATION OF haploid cells FOR FLOWCYTOMETRISYSTEMER
US7440101B2 (en) * 2004-01-23 2008-10-21 Beckman Coulter, Inc. System and method for multiple laser triggering
BRPI0509485A (pt) 2004-03-29 2007-09-11 Monsanto Technology Llc suspensões de esperma para uso em inseminação
JP4491277B2 (ja) * 2004-05-21 2010-06-30 株式会社日立ハイテクノロジーズ 試料分析装置
MX2007000888A (es) 2004-07-22 2007-04-02 Monsanto Technology Llc Procedimiento para enriquecer una poblacion de celulas de esperma.
US7522786B2 (en) * 2005-12-22 2009-04-21 Palo Alto Research Center Incorporated Transmitting light with photon energy information
US7291824B2 (en) * 2005-12-22 2007-11-06 Palo Alto Research Center Incorporated Photosensing throughout energy range and in subranges
US7310153B2 (en) 2004-08-23 2007-12-18 Palo Alto Research Center, Incorporated Using position-sensitive detectors for wavelength determination
WO2006036388A2 (fr) 2004-08-23 2006-04-06 U.S. Genomics, Inc. Systemes et procedes de detection et d'analyse de polymeres
US7525660B2 (en) * 2005-02-08 2009-04-28 Northrop Grumman Systems Corporation Systems and methods for use in detecting harmful aerosol particles
US7423751B2 (en) * 2005-02-08 2008-09-09 Northrop Grumman Corporation Systems and methods for use in detecting harmful aerosol particles
FR2884920B1 (fr) * 2005-04-21 2007-08-10 Horiba Abx Sa Sa Dispositif et procede d'analyse multiparametrique d'elements microscopiques
US7630076B2 (en) * 2005-07-26 2009-12-08 University Of Connecticut Dual-detector systems and methods having utility in biomolecular measurements
US7618770B2 (en) * 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US7433552B2 (en) 2005-12-22 2008-10-07 Palo Alto Research Center Incorporated Obtaining analyte information
US8437582B2 (en) * 2005-12-22 2013-05-07 Palo Alto Research Center Incorporated Transmitting light with lateral variation
US7386199B2 (en) * 2005-12-22 2008-06-10 Palo Alto Research Center Incorporated Providing light to channels or portions
US7420677B2 (en) * 2005-12-22 2008-09-02 Palo Alto Research Center Incorporated Sensing photon energies of optical signals
US7547904B2 (en) * 2005-12-22 2009-06-16 Palo Alto Research Center Incorporated Sensing photon energies emanating from channels or moving objects
US7358476B2 (en) 2005-12-22 2008-04-15 Palo Alto Research Center Incorporated Sensing photons from objects in channels
US7718948B2 (en) * 2006-12-04 2010-05-18 Palo Alto Research Center Incorporated Monitoring light pulses
US9164037B2 (en) 2007-01-26 2015-10-20 Palo Alto Research Center Incorporated Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances
US8821799B2 (en) 2007-01-26 2014-09-02 Palo Alto Research Center Incorporated Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity
US7554673B2 (en) * 2007-02-05 2009-06-30 Palo Alto Research Center Incorporated Obtaining information about analytes using optical cavity output light
US7502123B2 (en) * 2007-02-05 2009-03-10 Palo Alto Research Center Incorporated Obtaining information from optical cavity output light
US7936463B2 (en) 2007-02-05 2011-05-03 Palo Alto Research Center Incorporated Containing analyte in optical cavity structures
US7817276B2 (en) 2007-02-05 2010-10-19 Palo Alto Research Center Incorporated Distinguishing objects
US7633629B2 (en) * 2007-02-05 2009-12-15 Palo Alto Research Center Incorporated Tuning optical cavities
US7545513B2 (en) * 2007-02-05 2009-06-09 Palo Alto Research Center Incorporated Encoding optical cavity output light
CN101925809B (zh) * 2007-12-04 2013-03-27 粒子监测系统有限公司 用于粒子检测的二维光学成像方法和系统
US8320983B2 (en) 2007-12-17 2012-11-27 Palo Alto Research Center Incorporated Controlling transfer of objects affecting optical characteristics
WO2009086525A2 (fr) * 2007-12-27 2009-07-09 Luminex Corporation Modalité de rapporteur luminescent destinée à l'analyse d'un dosage
US7763856B2 (en) * 2008-01-31 2010-07-27 Palo Alto Research Center Incorporated Producing time variation in emanating light
US7817254B2 (en) * 2008-01-30 2010-10-19 Palo Alto Research Center Incorporated Obtaining information from time variation of sensing results
US8153950B2 (en) * 2008-12-18 2012-04-10 Palo Alto Research Center Incorporated Obtaining sensing results and/or data in response to object detection
US8373860B2 (en) * 2008-02-01 2013-02-12 Palo Alto Research Center Incorporated Transmitting/reflecting emanating light with time variation
US8629981B2 (en) 2008-02-01 2014-01-14 Palo Alto Research Center Incorporated Analyzers with time variation based on color-coded spatial modulation
JP4365439B2 (ja) * 2008-03-04 2009-11-18 三井造船株式会社 蛍光検出方法及び蛍光検出装置
MY162159A (en) * 2008-09-05 2017-05-31 Xtralis Technologies Ltd Detection of particle characteristics
CN102282465B (zh) * 2008-11-14 2014-04-16 罗伯特·博世有限公司 用于检测二醇的设备和方法
WO2010100501A1 (fr) 2009-03-04 2010-09-10 Malvern Instruments Limited Caractérisation des particules
US8675197B2 (en) * 2009-03-04 2014-03-18 Malvern Instruments, Ltd. Particle characterization
JP5321260B2 (ja) * 2009-06-11 2013-10-23 ソニー株式会社 光学的測定装置、並びにフローサイトメーター及び光学的測定方法
US8589851B2 (en) * 2009-12-15 2013-11-19 Memoir Systems, Inc. Intelligent memory system compiler
JP2011163787A (ja) * 2010-02-05 2011-08-25 Sony Corp 微小粒子分析装置及び微小粒子分析方法
US9074977B2 (en) 2010-05-07 2015-07-07 Stc.Unm Multinode acoustic focusing for parallel flow cytometry analysis applications
US8830451B1 (en) * 2010-05-07 2014-09-09 Stc.Unm Multinode acoustic focusing for parallel flow cytometry analysis applications
WO2012021587A2 (fr) * 2010-08-10 2012-02-16 Rait Securities, Llc Système et procédé pour la négociation électronique d'instruments financiers
US8570500B2 (en) * 2010-08-20 2013-10-29 Stratedigm, Inc. Detector arrangement for a flow cytometry system
US8618510B2 (en) * 2011-01-28 2013-12-31 The Regents Of The University Of Colorado Optically integrated microfluidic cytometers for high throughput screening of photophysical properties of cells or particles
US8723140B2 (en) 2011-08-09 2014-05-13 Palo Alto Research Center Incorporated Particle analyzer with spatial modulation and long lifetime bioprobes
US9029800B2 (en) 2011-08-09 2015-05-12 Palo Alto Research Center Incorporated Compact analyzer with spatial modulation and multiple intensity modulated excitation sources
JP5817369B2 (ja) * 2011-09-13 2015-11-18 ソニー株式会社 スペクトル解析装置及び微小粒子測定装置、並びにスペクトル解析あるいはスペクトルチャート表示のための方法及びプログラム
CA2853093C (fr) 2011-10-21 2020-01-14 Acea Biosciences, Inc. Systeme et procede permettant de detecter une lumiere induite par plusieurs sources d'excitation dans un canal de circulation
US9372143B2 (en) * 2013-05-15 2016-06-21 Captl Llc Scanning image flow cytometer
JP2015094737A (ja) * 2013-11-14 2015-05-18 ソニー株式会社 光照射装置、粒子分析装置および光照射方法
EP3071951B1 (fr) 2013-11-19 2019-10-30 ACEA Biosciences, Inc. Moteur optique pour cytomètre en flux, système de cytomètre en flux et procédés d'utilisation
US10261080B2 (en) 2013-11-19 2019-04-16 Acea Biosciences, Inc. Optical detection system for flow cytometer, flow cytometer system and methods of use
US10302565B2 (en) * 2014-02-19 2019-05-28 Arizona Board Of Regents On Behalf Of Arizona State University System and method for isotopic analysis of calcium using laser induced fluorescence
US9869628B2 (en) 2014-06-25 2018-01-16 Acea Biosciences, Inc. Methods of collecting cells from multi-well plates for use in flow cytometry
CN104200114B (zh) * 2014-09-10 2017-08-04 中国人民解放军军事医学科学院卫生装备研究所 流式细胞仪数据快速分析方法
US11740174B2 (en) 2014-10-09 2023-08-29 Kinetic River Corp. Apparatus and methods for particle analysis and autofluorescence discrimination
US10564088B2 (en) 2014-10-09 2020-02-18 Kinetic River Corp. Particle analysis and sorting apparatus and methods
US11965812B2 (en) 2014-10-09 2024-04-23 Kinetic River Corp. Apparatus and methods for particle analysis and autofluorescence discrimination
WO2016100954A1 (fr) 2014-12-19 2016-06-23 Captl Llc Cytométrie en flux utilisant un flux planaire de manière hydrodynamique
US9952136B2 (en) * 2015-01-21 2018-04-24 Stratedigm, Inc. Systems and methods for detecting a particle
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
US10024780B2 (en) 2015-12-18 2018-07-17 Abbott Laboratories (Diagnostics Division) Methods for detecting events in a flow cytometer
US10436697B2 (en) * 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
LU100777B1 (de) * 2018-04-23 2019-10-23 Cytena Gmbh Verfahren zum Untersuchen einer Flüssigkeit, die wenigstens eine Zelle und/oder wenigstens ein Partikel enthält
JP2020051936A (ja) * 2018-09-27 2020-04-02 ソニー株式会社 微小粒子測定装置及び微小粒子測定方法
US11255771B2 (en) * 2019-06-21 2022-02-22 Captl Llc Photon signal processing for particle detection
EP4089401B1 (fr) * 2021-05-10 2024-11-06 Siemens Aktiengesellschaft Dispositif de mesure et procédé de mesure d'au moins deux composants différents d'un fluide utilisant la diffusion raman et la chimiluminescence

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3918812A (en) * 1973-05-07 1975-11-11 Us Energy Diagnoses of disease states by fluorescent measurements utilizing scanning laser beams
US4006360A (en) * 1974-08-21 1977-02-01 Block Engineering, Inc. Method of discriminating between dyed particles and background fluorescence of the dye
NL180704C (nl) * 1976-06-14 Coulter Electronics Inrichting voor gelijktijdige optische meting van kenmerken van zich in een suspensie bevindende deeltjes.
US4100416A (en) * 1977-03-02 1978-07-11 Block Engineering, Inc. Serum fluorescence suppression
DE2732272C2 (de) * 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen
US4198567A (en) * 1977-10-25 1980-04-15 Peter Eneroth Method and apparatus for discrimination between scattered excitation radiation and low level fast decaying fluorescent radiation
US4415265A (en) * 1981-06-25 1983-11-15 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for aerosol particle absorption spectroscopy

Also Published As

Publication number Publication date
GB2153521A (en) 1985-08-21
CA1222394A (fr) 1987-06-02
GB2153521B (en) 1987-02-11
US4573796A (en) 1986-03-04
FR2557977A1 (fr) 1985-07-12
GB8432825D0 (en) 1985-02-06
DE3500247A1 (de) 1985-07-18
JPS60209147A (ja) 1985-10-21

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