FR2512024A1 - Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant - Google Patents

Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant Download PDF

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Publication number
FR2512024A1
FR2512024A1 FR8116347A FR8116347A FR2512024A1 FR 2512024 A1 FR2512024 A1 FR 2512024A1 FR 8116347 A FR8116347 A FR 8116347A FR 8116347 A FR8116347 A FR 8116347A FR 2512024 A1 FR2512024 A1 FR 2512024A1
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FR
France
Prior art keywords
formula
general formula
compounds
derivative
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8116347A
Other languages
English (en)
French (fr)
Other versions
FR2512024B1 (
Inventor
Charles Malen
Jean-Claude Poignant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Priority to FR8116347A priority Critical patent/FR2512024A1/fr
Priority to US06/408,451 priority patent/US4496557A/en
Priority to CA000409886A priority patent/CA1227481A/fr
Priority to AT82401567T priority patent/ATE12497T1/de
Priority to EP82401567A priority patent/EP0074304B1/fr
Priority to DE8282401567T priority patent/DE3262880D1/de
Priority to ES515232A priority patent/ES8400422A1/es
Priority to GR69103A priority patent/GR77595B/el
Priority to IL66650A priority patent/IL66650A/xx
Priority to JP57148452A priority patent/JPS5874673A/ja
Priority to ZA826252A priority patent/ZA826252B/xx
Priority to PT75471A priority patent/PT75471B/pt
Priority to AU87730/82A priority patent/AU8773082A/en
Priority to NZ201740A priority patent/NZ201740A/en
Publication of FR2512024A1 publication Critical patent/FR2512024A1/fr
Application granted granted Critical
Publication of FR2512024B1 publication Critical patent/FR2512024B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/18—[b, e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
FR8116347A 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant Granted FR2512024A1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR8116347A FR2512024A1 (fr) 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant
US06/408,451 US4496557A (en) 1981-08-27 1982-08-16 Tricyclic ethers, their preparation and the pharmaceutical compositions containing them
CA000409886A CA1227481A (fr) 1981-08-27 1982-08-20 Procede de preparation d'ethers tricycliques
EP82401567A EP0074304B1 (fr) 1981-08-27 1982-08-24 Ethers tricycliques, leur préparation et les compositions pharmaceutiques les contenant
DE8282401567T DE3262880D1 (en) 1981-08-27 1982-08-24 Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations
AT82401567T ATE12497T1 (de) 1981-08-27 1982-08-24 Tricyclische aether, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln.
ES515232A ES8400422A1 (es) 1981-08-27 1982-08-25 "procedimiento de preparacion de eteres triciclicos, asi como de sus sales de adicion con un acido mineral u organico terapeuticamente compatible".
GR69103A GR77595B ( ) 1981-08-27 1982-08-25
IL66650A IL66650A (en) 1981-08-27 1982-08-26 Dibenzoxepines and dibenzooxazepines,their preparation and pharmaceutical compositions containing them
JP57148452A JPS5874673A (ja) 1981-08-27 1982-08-26 三環式エ−テル化合物及びその製法並びに該化合物を有効成分とする製剤
ZA826252A ZA826252B (en) 1981-08-27 1982-08-26 Tricyclic ethers,their preparation and the pharmaceutical compositions containing them
PT75471A PT75471B (fr) 1981-08-27 1982-08-26 Procede de preparation d'ethers tricycliques
AU87730/82A AU8773082A (en) 1981-08-27 1982-08-26 Dibenzo (b,e)-oxepines and 1,4-oxazepines; dibenzo (b,d)- pyrans
NZ201740A NZ201740A (en) 1981-08-27 1982-08-27 Tricyclic ethers and pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8116347A FR2512024A1 (fr) 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
FR2512024A1 true FR2512024A1 (fr) 1983-03-04
FR2512024B1 FR2512024B1 ( ) 1984-01-06

Family

ID=9261704

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8116347A Granted FR2512024A1 (fr) 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant

Country Status (14)

Country Link
US (1) US4496557A ( )
EP (1) EP0074304B1 ( )
JP (1) JPS5874673A ( )
AT (1) ATE12497T1 ( )
AU (1) AU8773082A ( )
CA (1) CA1227481A ( )
DE (1) DE3262880D1 ( )
ES (1) ES8400422A1 ( )
FR (1) FR2512024A1 ( )
GR (1) GR77595B ( )
IL (1) IL66650A ( )
NZ (1) NZ201740A ( )
PT (1) PT75471B ( )
ZA (1) ZA826252B ( )

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8500273D0 (sv) * 1985-01-22 1985-01-22 Leo Ab Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder
EP0332246A1 (en) * 1988-03-11 1989-09-13 Akzo N.V. Tricyclic amine derivatives
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
US5006536A (en) * 1989-12-26 1991-04-09 Hoechst-Roussel Pharmaceuticals Inc. Thienobenzoxepins and analgesic compositions thereof
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
WO2006058160A2 (en) 2004-11-26 2006-06-01 Hologic, Inc. Integrated multi-mode mammography/tomosynthesis x-ray system and method
US7616801B2 (en) 2002-11-27 2009-11-10 Hologic, Inc. Image handling and display in x-ray mammography and tomosynthesis
US7577282B2 (en) 2002-11-27 2009-08-18 Hologic, Inc. Image handling and display in X-ray mammography and tomosynthesis
US8565372B2 (en) 2003-11-26 2013-10-22 Hologic, Inc System and method for low dose tomosynthesis
US8571289B2 (en) 2002-11-27 2013-10-29 Hologic, Inc. System and method for generating a 2D image from a tomosynthesis data set
US7123684B2 (en) * 2002-11-27 2006-10-17 Hologic, Inc. Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing
US10638994B2 (en) 2002-11-27 2020-05-05 Hologic, Inc. X-ray mammography with tomosynthesis
US8768026B2 (en) 2003-11-26 2014-07-01 Hologic, Inc. X-ray imaging with x-ray markers that provide adjunct information but preserve image quality
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
US7702142B2 (en) 2004-11-15 2010-04-20 Hologic, Inc. Matching geometry generation and display of mammograms and tomosynthesis images
US7245694B2 (en) 2005-08-15 2007-07-17 Hologic, Inc. X-ray mammography/tomosynthesis of patient's breast
US7465268B2 (en) 2005-11-18 2008-12-16 Senorx, Inc. Methods for asymmetrical irradiation of a body cavity
US8532745B2 (en) 2006-02-15 2013-09-10 Hologic, Inc. Breast biopsy and needle localization using tomosynthesis systems
US7630533B2 (en) 2007-09-20 2009-12-08 Hologic, Inc. Breast tomosynthesis with display of highlighted suspected calcifications
US7991106B2 (en) * 2008-08-29 2011-08-02 Hologic, Inc. Multi-mode tomosynthesis/mammography gain calibration and image correction using gain map information from selected projection angles
EP3311748A3 (en) 2008-09-04 2018-05-09 Hologic Inc. Integrated multi-mode mammography/tomosynthesis x-ray system
US9248311B2 (en) 2009-02-11 2016-02-02 Hologic, Inc. System and method for modifying a flexibility of a brachythereapy catheter
US9579524B2 (en) 2009-02-11 2017-02-28 Hologic, Inc. Flexible multi-lumen brachytherapy device
US8170320B2 (en) 2009-03-03 2012-05-01 Hologic, Inc. Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly
US10207126B2 (en) 2009-05-11 2019-02-19 Cytyc Corporation Lumen visualization and identification system for multi-lumen balloon catheter
ES2862525T3 (es) 2009-10-08 2021-10-07 Hologic Inc Sistema de biopsia de mama con aguja y método de uso
US9352172B2 (en) 2010-09-30 2016-05-31 Hologic, Inc. Using a guide member to facilitate brachytherapy device swap
AU2011312086B2 (en) 2010-10-05 2015-09-17 Hologic, Inc. Upright x-ray breast imaging with a CT mode, multiple tomosynthesis modes, and a mammography mode
WO2012071429A1 (en) 2010-11-26 2012-05-31 Hologic, Inc. User interface for medical image review workstation
US10342992B2 (en) 2011-01-06 2019-07-09 Hologic, Inc. Orienting a brachytherapy applicator
AU2012225398B2 (en) 2011-03-08 2017-02-02 Hologic, Inc. System and method for dual energy and/or contrast enhanced breast imaging for screening, diagnosis and biopsy
EP2782505B1 (en) 2011-11-27 2020-04-22 Hologic, Inc. System and method for generating a 2d image using mammography and/or tomosynthesis image data
JP6240097B2 (ja) 2012-02-13 2017-11-29 ホロジック インコーポレイティッド 合成画像データを使用してトモシンセシススタックをナビゲートする方法
US10092358B2 (en) 2013-03-15 2018-10-09 Hologic, Inc. Tomosynthesis-guided biopsy apparatus and method
EP3055837B1 (en) 2013-10-09 2021-08-04 Hologic, Inc. X-ray breast tomosynthesis enhancing spatial resolution including in the thickness direction of a flattened breast
EP3110332B1 (en) 2014-02-28 2018-04-11 Hologic Inc. System and method for generating and displaying tomosynthesis image slabs
AU2015343319B2 (en) 2014-11-07 2020-07-23 Hologic, Inc. Pivoting paddle apparatus for mammography/tomosynthesis x-ray system
JP7085492B2 (ja) 2016-04-22 2022-06-16 ホロジック，インコーポレイテッド アドレス指定可能なアレイを使用する偏移焦点ｘ線システムを用いるトモシンセシス
JP2019533510A (ja) 2016-11-08 2019-11-21 ホロジック, インコーポレイテッドHologic, Inc. 湾曲した圧迫要素を用いた撮像
WO2018183550A1 (en) 2017-03-30 2018-10-04 Hologic, Inc. System and method for targeted object enhancement to generate synthetic breast tissue images
JP7277053B2 (ja) 2017-03-30 2023-05-18 ホロジック， インコーポレイテッド 階層式マルチレベル特徴画像合成および提示のためのシステムおよび方法
EP3600051B1 (en) 2017-03-30 2024-05-01 Hologic, Inc. Method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement
US11403483B2 (en) 2017-06-20 2022-08-02 Hologic, Inc. Dynamic self-learning medical image method and system
WO2019033022A1 (en) 2017-08-11 2019-02-14 Hologic, Inc. BREAST COMPRESSION PLATE COMPRISING AN INFLATABLE ENVELOPE
US11672493B2 (en) 2017-08-11 2023-06-13 Hologic, Inc. Breast compression paddle with access corners
US11707244B2 (en) 2017-08-16 2023-07-25 Hologic, Inc. Techniques for breast imaging patient motion artifact compensation
EP3449835B1 (en) 2017-08-22 2023-01-11 Hologic, Inc. Computed tomography system and method for imaging multiple anatomical targets
US11090017B2 (en) 2018-09-13 2021-08-17 Hologic, Inc. Generating synthesized projection images for 3D breast tomosynthesis or multi-mode x-ray breast imaging
EP3832689A3 (en) 2019-12-05 2021-08-11 Hologic, Inc. Systems and methods for improved x-ray tube life
US11622736B2 (en) 2020-01-24 2023-04-11 Hologic, Inc. Horizontally-displaceable foam breast compression paddle
US11471118B2 (en) 2020-03-27 2022-10-18 Hologic, Inc. System and method for tracking x-ray tube focal spot position
US11786191B2 (en) 2021-05-17 2023-10-17 Hologic, Inc. Contrast-enhanced tomosynthesis with a copper filter

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1513909A (fr) * 1966-03-11 1968-02-16 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricycliques de l'éthylamine
FR1518226A (fr) * 1966-04-09 1968-03-22 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3609167A (en) * 1962-04-02 1971-09-28 Smith Kline French Lab IBENZO{8 b,e{9 {0 THIEPINES
NL125253C ( ) * 1963-12-05
US4463001A (en) * 1980-10-20 1984-07-31 Farmitalia Carlo Erba S.P.A. 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1513909A (fr) * 1966-03-11 1968-02-16 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricycliques de l'éthylamine
FR1518226A (fr) * 1966-04-09 1968-03-22 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1965 *
EXBK/65 *

Also Published As

Publication number Publication date
IL66650A (en) 1985-08-30
DE3262880D1 (en) 1985-05-09
US4496557A (en) 1985-01-29
EP0074304B1 (fr) 1985-04-03
JPS5874673A (ja) 1983-05-06
ZA826252B (en) 1983-07-27
FR2512024B1 ( ) 1984-01-06
PT75471A (fr) 1982-09-01
AU8773082A (en) 1983-03-03
JPS6129950B2 ( ) 1986-07-10
ES515232A0 (es) 1983-11-01
IL66650A0 (en) 1982-12-31
PT75471B (fr) 1984-11-19
EP0074304A1 (fr) 1983-03-16
ES8400422A1 (es) 1983-11-01
ATE12497T1 (de) 1985-04-15
GR77595B ( ) 1984-09-25
NZ201740A (en) 1985-05-31
CA1227481A (fr) 1987-09-29

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