FR2501506A1 - Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine - Google Patents

Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine Download PDF

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Publication number
FR2501506A1
FR2501506A1 FR8104891A FR8104891A FR2501506A1 FR 2501506 A1 FR2501506 A1 FR 2501506A1 FR 8104891 A FR8104891 A FR 8104891A FR 8104891 A FR8104891 A FR 8104891A FR 2501506 A1 FR2501506 A1 FR 2501506A1
Authority
FR
France
Prior art keywords
trifluoromethylphenyl
tetrahydropyridine
hydrochloride
active ingredient
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8104891A
Other languages
English (en)
French (fr)
Other versions
FR2501506B1 (enExample
Inventor
Dino Nisato
Alberto Bianchetti
Artemio Pessa
Paolo Carminati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8104891A priority Critical patent/FR2501506A1/fr
Priority to EP82400336A priority patent/EP0060179A1/fr
Priority to IL65170A priority patent/IL65170A0/xx
Priority to AU81112/82A priority patent/AU8111282A/en
Priority to ZA821519A priority patent/ZA821519B/xx
Priority to NZ199974A priority patent/NZ199974A/en
Priority to JP57037339A priority patent/JPS57159714A/ja
Priority to AT0096882A priority patent/AT379590B/de
Publication of FR2501506A1 publication Critical patent/FR2501506A1/fr
Application granted granted Critical
Publication of FR2501506B1 publication Critical patent/FR2501506B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR8104891A 1981-03-11 1981-03-11 Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine Granted FR2501506A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR8104891A FR2501506A1 (fr) 1981-03-11 1981-03-11 Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine
EP82400336A EP0060179A1 (fr) 1981-03-11 1982-02-26 Compositions pharmaceutiques à action anorexigène
AU81112/82A AU8111282A (en) 1981-03-11 1982-03-04 1,2,3,6 tetrahydropyridines as anorectic agents
IL65170A IL65170A0 (en) 1981-03-11 1982-03-04 Pharmaceutical compositions containing tetrahydropyridine derivatives or salts thereof
ZA821519A ZA821519B (en) 1981-03-11 1982-03-08 Pharmaceutical compositions having an anorectic action
NZ199974A NZ199974A (en) 1981-03-11 1982-03-10 Pharmaceutical compositions containing 4-(3-trifluoromethylphenyl-1,2,3,6-tetrahydropyridine derivatives
JP57037339A JPS57159714A (en) 1981-03-11 1982-03-11 Medicinal composition having appetite inhibition
AT0096882A AT379590B (de) 1981-03-11 1982-03-11 Verfahren zur herstellung von neuen 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridinderivaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8104891A FR2501506A1 (fr) 1981-03-11 1981-03-11 Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine

Publications (2)

Publication Number Publication Date
FR2501506A1 true FR2501506A1 (fr) 1982-09-17
FR2501506B1 FR2501506B1 (enExample) 1984-07-20

Family

ID=9256121

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8104891A Granted FR2501506A1 (fr) 1981-03-11 1981-03-11 Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine

Country Status (8)

Country Link
EP (1) EP0060179A1 (enExample)
JP (1) JPS57159714A (enExample)
AT (1) AT379590B (enExample)
AU (1) AU8111282A (enExample)
FR (1) FR2501506A1 (enExample)
IL (1) IL65170A0 (enExample)
NZ (1) NZ199974A (enExample)
ZA (1) ZA821519B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
DE3438394A1 (de) * 1984-10-19 1986-04-30 Merck Patent Gmbh, 6100 Darmstadt Pyridinderivate
JPH0269125U (enExample) * 1988-11-14 1990-05-25
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
SE9904723D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904724D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
US7851629B2 (en) 2004-06-08 2010-12-14 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
DE602005021641D1 (de) 2004-06-08 2010-07-15 Nsab, Filial Af Neurosearch Sweden Ab Neue disubstituierte phenylpiperidine und piperazine als modulatoren der dopamin-neurotransmission
SE0401465D0 (sv) 2004-06-08 2004-06-08 Carlsson A Research Ab New substituted piperdines as modulators of dopamine neurotransmission
CA2584831C (en) 2004-10-13 2013-09-17 Neurosearch Sweden Ab Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine
SE529246C2 (sv) 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
WO2013086425A1 (en) 2011-12-08 2013-06-13 IVAX International GmbH The hydrobromide salt of pridopidine
US20130267552A1 (en) 2012-04-04 2013-10-10 IVAX International GmbH Pharmaceutical compositions for combination therapy

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2498431A (en) * 1945-06-13 1950-02-21 Hoffmann La Roche 2-and 4-homocyclyl substituted piperidines
GB881894A (en) * 1958-04-22 1961-11-08 Paul Adriaan Jan Janssen Tetrahydropyridine derivatives
US3125488A (en) * 1964-03-17 Method of inducing analgesia by
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
FR1459013A (fr) * 1964-08-05 1966-04-29 Allen & Hanburys Ltd Procédé de préparation de dérivés de la 4-phényl-pipéridine
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
FR2070167A1 (enExample) * 1969-10-27 1971-09-10 Robins Co Inc A H
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
US3833576A (en) * 1970-06-17 1974-09-03 Hoffmann La Roche Process for the preparation of aromatic ethers and intermediates useful therefor
FR2340734A1 (fr) * 1976-02-13 1977-09-09 Roussel Uclaf Nouveaux derives de la m-trifluoromethylphenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523950A (en) * 1967-12-13 1970-08-11 Robins Co Inc A H Certain 4 - phenyl - 1,2,3,6 - tetrahydropyridyl-n-lower alkylene-ureas and derivatives

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125488A (en) * 1964-03-17 Method of inducing analgesia by
US2498431A (en) * 1945-06-13 1950-02-21 Hoffmann La Roche 2-and 4-homocyclyl substituted piperidines
GB881894A (en) * 1958-04-22 1961-11-08 Paul Adriaan Jan Janssen Tetrahydropyridine derivatives
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
FR1459013A (fr) * 1964-08-05 1966-04-29 Allen & Hanburys Ltd Procédé de préparation de dérivés de la 4-phényl-pipéridine
FR2070167A1 (enExample) * 1969-10-27 1971-09-10 Robins Co Inc A H
US3833576A (en) * 1970-06-17 1974-09-03 Hoffmann La Roche Process for the preparation of aromatic ethers and intermediates useful therefor
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
FR2340734A1 (fr) * 1976-02-13 1977-09-09 Roussel Uclaf Nouveaux derives de la m-trifluoromethylphenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments

Also Published As

Publication number Publication date
IL65170A0 (en) 1982-05-31
FR2501506B1 (enExample) 1984-07-20
AT379590B (de) 1986-01-27
ATA96882A (de) 1985-06-15
NZ199974A (en) 1985-05-31
JPS57159714A (en) 1982-10-01
EP0060179A1 (fr) 1982-09-15
ZA821519B (en) 1983-01-26
AU8111282A (en) 1982-09-16

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