FR2500305A1 - Procede de preparation d'un extrait de sperme, extrait obtenu selon ce procede et son utilisation notamment en therapeutique et en cosmetique - Google Patents
Procede de preparation d'un extrait de sperme, extrait obtenu selon ce procede et son utilisation notamment en therapeutique et en cosmetique Download PDFInfo
- Publication number
- FR2500305A1 FR2500305A1 FR8103653A FR8103653A FR2500305A1 FR 2500305 A1 FR2500305 A1 FR 2500305A1 FR 8103653 A FR8103653 A FR 8103653A FR 8103653 A FR8103653 A FR 8103653A FR 2500305 A1 FR2500305 A1 FR 2500305A1
- Authority
- FR
- France
- Prior art keywords
- sperm
- sep
- temperature
- centrifugation
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000284 extract Substances 0.000 title claims abstract description 35
- 239000006228 supernatant Substances 0.000 title claims abstract description 13
- 239000002537 cosmetic Substances 0.000 title claims abstract description 11
- 238000011084 recovery Methods 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000000470 constituent Substances 0.000 claims abstract description 11
- 239000003795 chemical substances by application Substances 0.000 claims abstract 2
- 239000007788 liquid Substances 0.000 claims description 49
- 238000005119 centrifugation Methods 0.000 claims description 29
- 238000000034 method Methods 0.000 claims description 20
- 210000000582 semen Anatomy 0.000 claims description 12
- 230000001954 sterilising effect Effects 0.000 claims description 11
- 238000004659 sterilization and disinfection Methods 0.000 claims description 11
- 239000000126 substance Substances 0.000 claims description 11
- 230000008569 process Effects 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 7
- 238000010257 thawing Methods 0.000 claims description 6
- 238000000502 dialysis Methods 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 4
- 238000000108 ultra-filtration Methods 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000012141 concentrate Substances 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 238000002347 injection Methods 0.000 abstract description 11
- 239000007924 injection Substances 0.000 abstract description 11
- 241000282414 Homo sapiens Species 0.000 abstract description 9
- 241001465754 Metazoa Species 0.000 abstract description 7
- 241000283073 Equus caballus Species 0.000 abstract description 5
- 241000282898 Sus scrofa Species 0.000 abstract description 4
- 230000006872 improvement Effects 0.000 abstract description 3
- 241000283690 Bos taurus Species 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 230000037394 skin elasticity Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 102100031357 L-lactate dehydrogenase C chain Human genes 0.000 description 11
- 108010028554 LDL Cholesterol Proteins 0.000 description 11
- 230000002255 enzymatic effect Effects 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 244000309464 bull Species 0.000 description 5
- 238000002560 therapeutic procedure Methods 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000282412 Homo Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000000349 chromosome Anatomy 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000004925 denaturation Methods 0.000 description 2
- 230000036425 denaturation Effects 0.000 description 2
- 210000004207 dermis Anatomy 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000011034 membrane dialysis Methods 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- 208000035404 Autolysis Diseases 0.000 description 1
- 206010057248 Cell death Diseases 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 208000024556 Mendelian disease Diseases 0.000 description 1
- 210000001766 X chromosome Anatomy 0.000 description 1
- 210000002593 Y chromosome Anatomy 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 235000008504 concentrate Nutrition 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 235000014666 liquid concentrate Nutrition 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 210000004940 nucleus Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000005132 reproductive cell Anatomy 0.000 description 1
- 230000028043 self proteolysis Effects 0.000 description 1
- 230000009758 senescence Effects 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/982—Reproductive organs; Embryos, Eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/52—Sperm; Prostate; Seminal fluid; Leydig cells of testes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8103653A FR2500305A1 (fr) | 1981-02-24 | 1981-02-24 | Procede de preparation d'un extrait de sperme, extrait obtenu selon ce procede et son utilisation notamment en therapeutique et en cosmetique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8103653A FR2500305A1 (fr) | 1981-02-24 | 1981-02-24 | Procede de preparation d'un extrait de sperme, extrait obtenu selon ce procede et son utilisation notamment en therapeutique et en cosmetique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2500305A1 true FR2500305A1 (fr) | 1982-08-27 |
| FR2500305B1 FR2500305B1 (Direct) | 1983-11-25 |
Family
ID=9255577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8103653A Granted FR2500305A1 (fr) | 1981-02-24 | 1981-02-24 | Procede de preparation d'un extrait de sperme, extrait obtenu selon ce procede et son utilisation notamment en therapeutique et en cosmetique |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2500305A1 (Direct) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008020329A3 (en) * | 2006-05-11 | 2009-10-22 | Regenics As | Administration of cells and cellular extracts for rejuvenation |
| US8557295B2 (en) | 2006-05-11 | 2013-10-15 | Regenics As | Use of cellular extracts for skin rejuvenation |
| US8877253B2 (en) | 2006-05-11 | 2014-11-04 | Regenics As | Cellular extracts |
| US11007385B2 (en) | 2012-12-10 | 2021-05-18 | Regenics As | Use of cellular extracts for skin rejuvenation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU104096A1 (ru) * | 1955-04-28 | 1955-11-30 | Г.М. Беленькая | Препарат "Ронидаза" |
| DE2032988A1 (en) * | 1970-07-03 | 1972-01-05 | Theurer, Karl, Dr. med., 7000 Stuttgart | Ovular and seminal cell extracts - having a haploid chromosome set for therapeutic and diagnostic use |
| US3917816A (en) * | 1970-05-26 | 1975-11-04 | Gen Mills Chem Inc | Protein conditioner |
-
1981
- 1981-02-24 FR FR8103653A patent/FR2500305A1/fr active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU104096A1 (ru) * | 1955-04-28 | 1955-11-30 | Г.М. Беленькая | Препарат "Ронидаза" |
| US3917816A (en) * | 1970-05-26 | 1975-11-04 | Gen Mills Chem Inc | Protein conditioner |
| DE2032988A1 (en) * | 1970-07-03 | 1972-01-05 | Theurer, Karl, Dr. med., 7000 Stuttgart | Ovular and seminal cell extracts - having a haploid chromosome set for therapeutic and diagnostic use |
Non-Patent Citations (2)
| Title |
|---|
| CA1957 * |
| EXBK/77 * |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8920848B2 (en) | 2006-05-11 | 2014-12-30 | Regenics As | Use of cellular extracts for skin rejuvenation |
| US9999639B2 (en) | 2006-05-11 | 2018-06-19 | Regenics As | Cellular extracts |
| US8460713B2 (en) | 2006-05-11 | 2013-06-11 | Regenics As | Administration of cells and cellular extracts for rejuvenation |
| US8557295B2 (en) | 2006-05-11 | 2013-10-15 | Regenics As | Use of cellular extracts for skin rejuvenation |
| EP2656832A3 (en) * | 2006-05-11 | 2014-08-06 | Regenics AS | Administration of cells and cellular extracts for rejuvenation |
| US8877253B2 (en) | 2006-05-11 | 2014-11-04 | Regenics As | Cellular extracts |
| US8075920B2 (en) | 2006-05-11 | 2011-12-13 | Regenics A/S | Administration of cells and cellular extracts for rejuvenation |
| US9314488B2 (en) | 2006-05-11 | 2016-04-19 | Regenics As | Cellular extracts |
| WO2008020329A3 (en) * | 2006-05-11 | 2009-10-22 | Regenics As | Administration of cells and cellular extracts for rejuvenation |
| US9486401B2 (en) | 2006-05-11 | 2016-11-08 | Regenics As | Use of cellular extracts for skin rejuvenation |
| US9066883B2 (en) | 2006-05-11 | 2015-06-30 | Regenics As | Administration of cells and cellular extracts for rejuvenation |
| US10092504B2 (en) | 2006-05-11 | 2018-10-09 | Regenics As | Use of cellular extracts for skin rejuvenation |
| US10478461B2 (en) | 2006-05-11 | 2019-11-19 | Regenics As | Cellular extracts |
| US11033587B2 (en) | 2006-05-11 | 2021-06-15 | Regenics As | Administration of cells and cellular extracts for rejuvenation |
| US11007385B2 (en) | 2012-12-10 | 2021-05-18 | Regenics As | Use of cellular extracts for skin rejuvenation |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2500305B1 (Direct) | 1983-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |