FR2497101A1 - Production d'hormone stimulation de la thyroide humaine - Google Patents
Production d'hormone stimulation de la thyroide humaine Download PDFInfo
- Publication number
- FR2497101A1 FR2497101A1 FR8124269A FR8124269A FR2497101A1 FR 2497101 A1 FR2497101 A1 FR 2497101A1 FR 8124269 A FR8124269 A FR 8124269A FR 8124269 A FR8124269 A FR 8124269A FR 2497101 A1 FR2497101 A1 FR 2497101A1
- Authority
- FR
- France
- Prior art keywords
- human
- cells
- hsth
- line
- multiplication
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 229940088597 hormone Drugs 0.000 title claims abstract description 18
- 239000005556 hormone Substances 0.000 title claims abstract description 18
- 210000001685 thyroid gland Anatomy 0.000 title claims abstract description 4
- 230000000638 stimulation Effects 0.000 title 1
- 241001465754 Metazoa Species 0.000 claims abstract description 32
- 238000000034 method Methods 0.000 claims abstract description 31
- 230000004936 stimulating effect Effects 0.000 claims abstract description 4
- 102000011923 Thyrotropin Human genes 0.000 claims abstract description 3
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
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- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
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- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 2
- 241000124008 Mammalia Species 0.000 claims description 2
- 241000699666 Mus <mouse, genus> Species 0.000 claims description 2
- 241000009328 Perro Species 0.000 claims description 2
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- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- 235000018417 cysteine Nutrition 0.000 claims description 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 2
- 229960000874 thyrotropin Drugs 0.000 claims description 2
- 230000001748 thyrotropin Effects 0.000 claims description 2
- 102000016605 B-Cell Activating Factor Human genes 0.000 claims 1
- 108010028006 B-Cell Activating Factor Proteins 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims 1
- 241000018646 Pinus brutia Species 0.000 claims 1
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- 230000001456 gonadotroph Effects 0.000 claims 1
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- 230000013011 mating Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 abstract description 8
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- 210000002966 serum Anatomy 0.000 description 4
- 238000000605 extraction Methods 0.000 description 3
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- 235000019766 L-Lysine Nutrition 0.000 description 1
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- 239000000627 Thyrotropin-Releasing Hormone Substances 0.000 description 1
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- 239000001103 potassium chloride Substances 0.000 description 1
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M potassium chloride Inorganic materials [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- XNSAINXGIQZQOO-SRVKXCTJSA-N protirelin Chemical compound NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-SRVKXCTJSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55187010A JPS5826317B2 (ja) | 1980-12-30 | 1980-12-30 | ヒト甲状腺刺激ホルモンの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2497101A1 true FR2497101A1 (fr) | 1982-07-02 |
| FR2497101B1 FR2497101B1 (oth) | 1984-11-09 |
Family
ID=16198616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8124269A Granted FR2497101A1 (fr) | 1980-12-30 | 1981-12-28 | Production d'hormone stimulation de la thyroide humaine |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5826317B2 (oth) |
| KR (1) | KR860001589B1 (oth) |
| CH (1) | CH652747A5 (oth) |
| FR (1) | FR2497101A1 (oth) |
| GB (1) | GB2092156B (oth) |
| IT (1) | IT1148019B (oth) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS609795B2 (ja) * | 1980-12-11 | 1985-03-13 | 株式会社林原生物化学研究所 | ヒト上皮細胞成長因子の製造方法 |
| GB9015327D0 (en) * | 1990-07-12 | 1990-08-29 | Tan Kim S | Hybridomas |
| KR101789509B1 (ko) * | 2015-11-05 | 2017-10-26 | 주식회사 프로젠 | 재조합 인간 갑상선 자극 호르몬을 포함하는 조성물 및 상기 재조합 인간 갑상선 자극 호르몬의 생산 방법 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2414920A1 (fr) * | 1978-01-22 | 1979-08-17 | Hayashibara Ken | Interferon et preparation le contenant |
| FR2446637A1 (fr) * | 1979-01-18 | 1980-08-14 | Hayashibara Ken | Procede pour preparer de l'interferon de type ii et preparations contenant de l'interferon de type ii |
-
1980
- 1980-12-30 JP JP55187010A patent/JPS5826317B2/ja not_active Expired
-
1981
- 1981-12-21 CH CH8155/81A patent/CH652747A5/fr not_active IP Right Cessation
- 1981-12-22 GB GB8138587A patent/GB2092156B/en not_active Expired
- 1981-12-22 IT IT49978/81A patent/IT1148019B/it active
- 1981-12-23 KR KR1019810005089A patent/KR860001589B1/ko not_active Expired
- 1981-12-28 FR FR8124269A patent/FR2497101A1/fr active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2414920A1 (fr) * | 1978-01-22 | 1979-08-17 | Hayashibara Ken | Interferon et preparation le contenant |
| FR2446637A1 (fr) * | 1979-01-18 | 1980-08-14 | Hayashibara Ken | Procede pour preparer de l'interferon de type ii et preparations contenant de l'interferon de type ii |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2092156B (en) | 1984-05-10 |
| IT1148019B (it) | 1986-11-26 |
| KR860001589B1 (ko) | 1986-10-13 |
| FR2497101B1 (oth) | 1984-11-09 |
| CH652747A5 (fr) | 1985-11-29 |
| JPS57115180A (en) | 1982-07-17 |
| KR830007087A (ko) | 1983-10-14 |
| GB2092156A (en) | 1982-08-11 |
| JPS5826317B2 (ja) | 1983-06-02 |
| IT8149978A0 (it) | 1981-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |