FR2494274B2 - - Google Patents

Info

Publication number
FR2494274B2
FR2494274B2 FR8024633A FR8024633A FR2494274B2 FR 2494274 B2 FR2494274 B2 FR 2494274B2 FR 8024633 A FR8024633 A FR 8024633A FR 8024633 A FR8024633 A FR 8024633A FR 2494274 B2 FR2494274 B2 FR 2494274B2
Authority
FR
France
Prior art keywords
general formula
alkyl
radical
hydrogen
cyanomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8024633A
Other languages
English (en)
French (fr)
Other versions
FR2494274A2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Priority to FR8024633A priority Critical patent/FR2494274A2/fr
Priority to PT73996A priority patent/PT73996B/pt
Priority to AU77586/81A priority patent/AU543289B2/en
Priority to AT81401822T priority patent/ATE10001T1/de
Priority to DE8181401822T priority patent/DE3166867D1/de
Priority to NO813939A priority patent/NO813939L/no
Priority to DK513281A priority patent/DK513281A/da
Priority to ES507281A priority patent/ES507281A0/es
Priority to SU813354006A priority patent/SU1160936A3/ru
Priority to IE2716/81A priority patent/IE52784B1/en
Priority to ZA818034A priority patent/ZA818034B/xx
Priority to CA000390469A priority patent/CA1200542A/fr
Priority to HU813461A priority patent/HU186796B/hu
Priority to EP81401822A priority patent/EP0053961B1/fr
Priority to US06/322,901 priority patent/US4415562A/en
Priority to JP56185559A priority patent/JPS57114592A/ja
Priority to FI813693A priority patent/FI813693A7/fi
Priority to ES509194A priority patent/ES509194A0/es
Publication of FR2494274A2 publication Critical patent/FR2494274A2/fr
Application granted granted Critical
Publication of FR2494274B2 publication Critical patent/FR2494274B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR8024633A 1980-11-20 1980-11-20 Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent Granted FR2494274A2 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR8024633A FR2494274A2 (fr) 1980-11-20 1980-11-20 Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent
PT73996A PT73996B (fr) 1980-11-20 1981-11-16 Thiovinyl-3 cephalosporines
AU77586/81A AU543289B2 (en) 1980-11-20 1981-11-18 3-thiovinylcephalosporins
HU813461A HU186796B (en) 1980-11-20 1981-11-19 Process for preparing new 3-thio-vinyl-cefem-derivatives
NO813939A NO813939L (no) 1980-11-20 1981-11-19 Fremgangsmaate for fremstilling av nye 3-tiovinylcefalosporiner
DK513281A DK513281A (da) 1980-11-20 1981-11-19 Fremgangsaade til fremstilling af 3-thiovinylcephalosproner
ES507281A ES507281A0 (es) 1980-11-20 1981-11-19 Procedimiento para la preparacion de una nueva tiovinil-3 cefalosporina.
SU813354006A SU1160936A3 (ru) 1980-11-20 1981-11-19 Способ получени 3-тиовинилцефалоспоринов
AT81401822T ATE10001T1 (de) 1980-11-20 1981-11-19 Thiovinyl-3-cephalosporinverbindungen, ihre herstellung und sie enthaltende pharmazeutische praeparate.
ZA818034A ZA818034B (en) 1980-11-20 1981-11-19 New 3-thiovinyl cephalosporins,their preparation and the pharmaceutical compositions in which they are present
CA000390469A CA1200542A (fr) 1980-11-20 1981-11-19 Thiovinyl-3 cephalosporines, leur preparation et les compositions pharmaceutiques qui les contiennent
DE8181401822T DE3166867D1 (en) 1980-11-20 1981-11-19 Thiovinyl-3-cephalosporin derivatives, their preparation and pharmaceutical compositions containing them
EP81401822A EP0053961B1 (fr) 1980-11-20 1981-11-19 Nouvelles thiovinyl-3 céphalosporines, leur préparation et les compositions pharmaceutiques qui les contiennent
US06/322,901 US4415562A (en) 1980-11-20 1981-11-19 3-Thiovinylcephalosporins and pharmaceutical compositions
IE2716/81A IE52784B1 (en) 1980-11-20 1981-11-19 New 3-thiovinyl cephalosporins, their preparation and the pharmaceutical compositions in which they are present
JP56185559A JPS57114592A (en) 1980-11-20 1981-11-20 3-thiovinylcephalosporins and manufacture
FI813693A FI813693A7 (fi) 1980-11-20 1981-11-20 Uudet 3-tiovinyyli-kefalosporiinit, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset vvalmisteet.
ES509194A ES509194A0 (es) 1980-11-20 1982-01-29 Procedimiento para la preparacion de una nueva tiovinil-3 cefalosporina.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8024633A FR2494274A2 (fr) 1980-11-20 1980-11-20 Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
FR2494274A2 FR2494274A2 (fr) 1982-05-21
FR2494274B2 true FR2494274B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-04-29

Family

ID=9248167

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8024633A Granted FR2494274A2 (fr) 1980-11-20 1980-11-20 Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent

Country Status (17)

Country Link
US (1) US4415562A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0053961B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS57114592A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE10001T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU543289B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1200542A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3166867D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK513281A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES507281A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI813693A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2494274A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU186796B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE52784B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO813939L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT73996B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1160936A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA818034B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79043B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1982-12-06 1984-10-02 Fujisawa Pharmaceutical Co
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
EP1478649A4 (en) * 2002-02-28 2006-09-13 Lg Life Sciences Ltd NOVEL CEPHALOSPORINE-BASED COMPOUNDS AND METHOD OF MANUFACTURING THE SAME

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
IE50626B1 (en) * 1979-05-23 1986-05-28 Rhone Poulenc Ind Novel 3-thiovinyl-cephalosporins,their preparation,and the compositions containing these compounds

Also Published As

Publication number Publication date
JPS57114592A (en) 1982-07-16
AU543289B2 (en) 1985-04-18
FR2494274A2 (fr) 1982-05-21
FI813693L (fi) 1982-05-21
NO813939L (no) 1982-05-21
ZA818034B (en) 1982-10-27
ES8302000A1 (es) 1983-01-16
FI813693A7 (fi) 1982-05-21
ES509194A0 (es) 1983-01-16
ES8300114A1 (es) 1982-10-01
EP0053961B1 (fr) 1984-10-24
CA1200542A (fr) 1986-02-11
HU186796B (en) 1985-09-30
ES507281A0 (es) 1982-10-01
EP0053961A1 (fr) 1982-06-16
DE3166867D1 (en) 1984-11-29
US4415562A (en) 1983-11-15
IE812716L (en) 1982-05-20
PT73996B (fr) 1983-04-14
SU1160936A3 (ru) 1985-06-07
PT73996A (fr) 1981-12-01
ATE10001T1 (de) 1984-11-15
AU7758681A (en) 1982-05-27
DK513281A (da) 1982-05-21
IE52784B1 (en) 1988-03-02

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