FR2492385B1 - Nouveaux composes cytostatiques derives de la vinblastine, leur procede de preparation et composition pharmaceutique les contenant - Google Patents
Nouveaux composes cytostatiques derives de la vinblastine, leur procede de preparation et composition pharmaceutique les contenantInfo
- Publication number
- FR2492385B1 FR2492385B1 FR8115836A FR8115836A FR2492385B1 FR 2492385 B1 FR2492385 B1 FR 2492385B1 FR 8115836 A FR8115836 A FR 8115836A FR 8115836 A FR8115836 A FR 8115836A FR 2492385 B1 FR2492385 B1 FR 2492385B1
- Authority
- FR
- France
- Prior art keywords
- vinblastin
- preparation
- pharmaceutical composition
- composition containing
- compounds derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000824 cytostatic agent Substances 0.000 title 1
- 230000001085 cytostatic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- JXLYSJRDGCGARV-CFWMRBGOSA-N vinblastine Chemical compound C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-CFWMRBGOSA-N 0.000 title 1
- 229960003048 vinblastine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU802563A HU181746B (en) | 1980-10-22 | 1980-10-22 | Process for preparing vinblastine and leurosidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2492385A1 FR2492385A1 (fr) | 1982-04-23 |
| FR2492385B1 true FR2492385B1 (fr) | 1985-08-02 |
Family
ID=10960009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8115836A Expired FR2492385B1 (fr) | 1980-10-22 | 1981-08-17 | Nouveaux composes cytostatiques derives de la vinblastine, leur procede de preparation et composition pharmaceutique les contenant |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4410459A (en:Method) |
| JP (1) | JPS5772993A (en:Method) |
| AT (1) | AT376679B (en:Method) |
| BE (1) | BE889990A (en:Method) |
| CA (1) | CA1182450A (en:Method) |
| CH (1) | CH648321A5 (en:Method) |
| DE (1) | DE3132475A1 (en:Method) |
| ES (1) | ES505311A0 (en:Method) |
| FR (1) | FR2492385B1 (en:Method) |
| GB (1) | GB2086884B (en:Method) |
| HU (1) | HU181746B (en:Method) |
| IL (1) | IL63594A0 (en:Method) |
| IT (1) | IT1138155B (en:Method) |
| NL (1) | NL8103843A (en:Method) |
| SE (1) | SE442117B (en:Method) |
| SU (1) | SU1138033A3 (en:Method) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU193318B (en) * | 1985-06-12 | 1987-09-28 | Richter Gedeon Vegyeszet | Process for producing new bis- indol derivatives |
| HU198074B (en) * | 1985-06-12 | 1989-07-28 | Richter Gedeon Vegyeszet | Process for producing new bis-indole derivatives and pharmaceutical compositions comprising these compounds |
| JPH0747233B2 (ja) * | 1987-09-14 | 1995-05-24 | 古河電気工業株式会社 | 半田析出用組成物および半田析出方法 |
| US5095109A (en) * | 1989-06-08 | 1992-03-10 | University Of Vermont | Novel alkaloids |
| US5938163A (en) * | 1997-10-20 | 1999-08-17 | Eastman Kodak Company | Articulating touchscreen interface |
| US20130178618A1 (en) | 2012-01-10 | 2013-07-11 | William Allen Boulanger | Novel pharmaceutical intermediates and methods for preparing the same |
| US12116372B1 (en) | 2023-12-14 | 2024-10-15 | William Allen Boulanger | Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4075214A (en) * | 1976-05-17 | 1978-02-21 | Eli Lilly And Company | Preparation of leurosidine and novel leurosidine 4'-ethers and esters |
| US4143041A (en) * | 1977-01-19 | 1979-03-06 | Eli Lilly And Company | 4'-Deoxyvincristine and related compounds |
| HU178706B (en) * | 1979-04-23 | 1982-06-28 | Richter Gedeon Vegyeszet | Process for preparing bis-indole alkaloids and acid addition salts thereof |
| JPS56128642A (en) * | 1980-03-15 | 1981-10-08 | Kubota Ltd | Production of frozen mold |
-
1980
- 1980-10-22 HU HU802563A patent/HU181746B/hu not_active IP Right Cessation
-
1981
- 1981-08-17 BE BE0/205692A patent/BE889990A/fr not_active IP Right Cessation
- 1981-08-17 JP JP56128643A patent/JPS5772993A/ja active Granted
- 1981-08-17 CA CA000384003A patent/CA1182450A/en not_active Expired
- 1981-08-17 FR FR8115836A patent/FR2492385B1/fr not_active Expired
- 1981-08-17 US US06/293,611 patent/US4410459A/en not_active Expired - Fee Related
- 1981-08-17 IL IL63594A patent/IL63594A0/xx not_active IP Right Cessation
- 1981-08-17 CH CH5314/81A patent/CH648321A5/de not_active IP Right Cessation
- 1981-08-17 ES ES505311A patent/ES505311A0/es active Granted
- 1981-08-17 NL NL8103843A patent/NL8103843A/nl not_active Application Discontinuation
- 1981-08-17 GB GB8125031A patent/GB2086884B/en not_active Expired
- 1981-08-17 DE DE3132475A patent/DE3132475A1/de active Granted
- 1981-08-17 SE SE8104878A patent/SE442117B/sv not_active IP Right Cessation
- 1981-08-17 SU SU813320102A patent/SU1138033A3/ru active
- 1981-08-17 IT IT23541/81A patent/IT1138155B/it active
- 1981-08-17 AT AT0358781A patent/AT376679B/de not_active IP Right Cessation
-
1983
- 1983-06-13 US US06/503,791 patent/US4490378A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB2086884B (en) | 1984-07-25 |
| SE8104878L (sv) | 1982-04-23 |
| NL8103843A (nl) | 1982-05-17 |
| IL63594A0 (en) | 1981-11-30 |
| AT376679B (de) | 1984-12-27 |
| SU1138033A3 (ru) | 1985-01-30 |
| DE3132475A1 (de) | 1982-06-24 |
| CA1182450A (en) | 1985-02-12 |
| BE889990A (fr) | 1982-02-17 |
| US4410459A (en) | 1983-10-18 |
| IT1138155B (it) | 1986-09-17 |
| ATA358781A (de) | 1984-05-15 |
| IT8123541A0 (it) | 1981-08-17 |
| DE3132475C2 (en:Method) | 1991-04-11 |
| US4490378A (en) | 1984-12-25 |
| JPH0161119B2 (en:Method) | 1989-12-27 |
| SE442117B (sv) | 1985-12-02 |
| FR2492385A1 (fr) | 1982-04-23 |
| ES8300778A1 (es) | 1982-12-01 |
| GB2086884A (en) | 1982-05-19 |
| CH648321A5 (de) | 1985-03-15 |
| HU181746B (en) | 1983-11-28 |
| JPS5772993A (en) | 1982-05-07 |
| ES505311A0 (es) | 1982-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |