FR2488255A1 - Propenimidamides substitues, leur preparation et leurs utilisations therapeutiques - Google Patents

Propenimidamides substitues, leur preparation et leurs utilisations therapeutiques Download PDF

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Publication number
FR2488255A1
FR2488255A1 FR8111043A FR8111043A FR2488255A1 FR 2488255 A1 FR2488255 A1 FR 2488255A1 FR 8111043 A FR8111043 A FR 8111043A FR 8111043 A FR8111043 A FR 8111043A FR 2488255 A1 FR2488255 A1 FR 2488255A1
Authority
FR
France
Prior art keywords
formula
cyano
phenyl
compounds according
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8111043A
Other languages
English (en)
French (fr)
Other versions
FR2488255B1 (enExample
Inventor
Tsuyoshi Tomiyama
Akira Tomiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kotobuki Seiyaku Co Ltd
Original Assignee
Kotobuki Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10906080A external-priority patent/JPS5735555A/ja
Priority claimed from JP15434880A external-priority patent/JPS5777662A/ja
Application filed by Kotobuki Seiyaku Co Ltd filed Critical Kotobuki Seiyaku Co Ltd
Publication of FR2488255A1 publication Critical patent/FR2488255A1/fr
Application granted granted Critical
Publication of FR2488255B1 publication Critical patent/FR2488255B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/44—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups doubly-bound to carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8111043A 1980-08-08 1981-06-04 Propenimidamides substitues, leur preparation et leurs utilisations therapeutiques Granted FR2488255A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10906080A JPS5735555A (en) 1980-08-08 1980-08-08 3-substituted 2-propenenitrile derivative and its preparation
JP15434880A JPS5777662A (en) 1980-11-01 1980-11-01 3-substituted 2-propenenitrile derivative and its preparation

Publications (2)

Publication Number Publication Date
FR2488255A1 true FR2488255A1 (fr) 1982-02-12
FR2488255B1 FR2488255B1 (enExample) 1984-12-28

Family

ID=26448850

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8111043A Granted FR2488255A1 (fr) 1980-08-08 1981-06-04 Propenimidamides substitues, leur preparation et leurs utilisations therapeutiques

Country Status (4)

Country Link
US (1) US4407816A (enExample)
DE (1) DE3122540A1 (enExample)
FR (1) FR2488255A1 (enExample)
GB (1) GB2085871B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN158869B (enExample) * 1981-03-18 1987-02-07 Ici Plc
EP0067508B1 (en) * 1981-05-18 1985-10-30 Imperial Chemical Industries Plc Amidine derivatives
JPH0662567B2 (ja) * 1988-12-27 1994-08-17 麒麟麦酒株式会社 ピリジンカルボキシイミダミド誘導体、その製造中間体、製造法および用途
US5272164A (en) * 1988-12-27 1993-12-21 Kirin Beer Kabushiki Kaisha Carboximidamide derivatives
US7241776B2 (en) * 2004-08-02 2007-07-10 Abbott Laboratories Cyanoamidine P2X7 antagonists for the treatment of pain

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1181693B (de) * 1963-04-01 1964-11-19 Hoechst Ag Verfahren zur Herstellung von Harnstoffen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5444660A (en) * 1977-08-29 1979-04-09 Yamanouchi Pharmaceut Co Ltd Heterocyclic compound and its preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1181693B (de) * 1963-04-01 1964-11-19 Hoechst Ag Verfahren zur Herstellung von Harnstoffen

Also Published As

Publication number Publication date
FR2488255B1 (enExample) 1984-12-28
DE3122540A1 (de) 1982-03-25
GB2085871A (en) 1982-05-06
US4407816A (en) 1983-10-04
GB2085871B (en) 1984-07-25

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