FR2485564B1 - Procede pour la production enzymatique de l-carnitine - Google Patents

Procede pour la production enzymatique de l-carnitine

Info

Publication number
FR2485564B1
FR2485564B1 FR8112332A FR8112332A FR2485564B1 FR 2485564 B1 FR2485564 B1 FR 2485564B1 FR 8112332 A FR8112332 A FR 8112332A FR 8112332 A FR8112332 A FR 8112332A FR 2485564 B1 FR2485564 B1 FR 2485564B1
Authority
FR
France
Prior art keywords
carnitine
enzymatic production
enzymatic
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8112332A
Other languages
English (en)
French (fr)
Other versions
FR2485564A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of FR2485564A1 publication Critical patent/FR2485564A1/fr
Application granted granted Critical
Publication of FR2485564B1 publication Critical patent/FR2485564B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/007Carnitine; Butyrobetaine; Crotonobetaine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01108Carnitine 3-dehydrogenase (1.1.1.108)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
FR8112332A 1980-06-24 1981-06-23 Procede pour la production enzymatique de l-carnitine Expired FR2485564B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT86253/80A IT1142201B (it) 1980-06-24 1980-06-24 Procedimento per la produzione enzimatica di l-carnitina

Publications (2)

Publication Number Publication Date
FR2485564A1 FR2485564A1 (fr) 1981-12-31
FR2485564B1 true FR2485564B1 (fr) 1985-07-12

Family

ID=11330417

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8112332A Expired FR2485564B1 (fr) 1980-06-24 1981-06-23 Procede pour la production enzymatique de l-carnitine

Country Status (9)

Country Link
US (1) US4371618A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5739791A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT379615B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH650274A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3123975A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2485564B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2078742B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1142201B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE443803B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642290A (en) * 1982-12-06 1987-02-10 Sih Charles J Process for preparing a compound for use in the production of L-carnitine
JPS59183694A (ja) * 1983-04-05 1984-10-18 Hamari Yakuhin Kogyo Kk 光学活性なカルニチンの生化学的製造法
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc L−カルニチンの製造法
US4710468A (en) * 1983-10-24 1987-12-01 Sigma-Tau Industrie Pharmaceutiche Riunite S.P.A. Process for preparing L-carnitine and chemical intermediates employed therein
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
US4584270A (en) * 1984-01-23 1986-04-22 Wisconsin Alumni Research Foundation Process for preparing optically-active 4-amino-3-hydroxybutyric acid
FI86889C (fi) * 1984-03-29 1992-10-26 Lonza Ag Foerfarande foer framstaellning av av l-karnitin pao mikrobiologiskt saett
ZA852808B (en) * 1984-04-20 1985-11-27 Wisconsin Alumni Res Found Process for preparing l-carnitine
US4751182A (en) * 1984-04-20 1988-06-14 Wisconsin Alumni Research Foundation Process for preparing L-carnitine from DL-carnitine
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
US5248601A (en) * 1986-03-14 1993-09-28 Franco Francalanci Process for preparing L(-)-carnitine chloride
GB2195630B (en) * 1986-08-26 1990-07-18 Chuo Kaseihin Co Inc Method for producing carnitine, l-carnitineamide hydrolase and method for producing same
JPH0669381B2 (ja) * 1987-12-04 1994-09-07 協和醗酵工業株式会社 カルニチンの製造法
JPH0291049A (ja) * 1988-09-21 1990-03-30 Lonza Ag r―ブチロベタインの製造方法
CA2018137C (en) * 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
KR100255039B1 (ko) 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
SI1151130T1 (en) 1998-10-27 2005-06-30 Sigma-Tau Coenzyme useful for the synthesis of l-carnitine
US6337197B2 (en) * 1998-10-27 2002-01-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Coenzymes useful for the synthesis of L-carnitine
DE10315760A1 (de) * 2003-04-07 2004-10-21 Basf Ag L-Carnitin Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von substituierten (S)-Alkanolen
KR100565732B1 (ko) * 2004-02-26 2006-03-28 씨제이 주식회사 뉴로스포라 크라사 기원의 감마부티로베타인 하이드록실라제
KR100713103B1 (ko) 2005-07-07 2007-05-02 씨제이 주식회사 뉴로스포라 크라사 유래 l-카르니틴 생합성 관련 유전자를포함하는 엔테로박테리아세 속 미생물 및 이를 이용한l-카르니틴의 제조방법
DE602005022120D1 (de) 2005-07-19 2010-08-12 Cj Cheiljedang Corp Mikroorganismus der gattung enterobacteriacae mit genen in zusammenhang mit der biosynthese von l-carnitin sowie verfahren zur produktion von l-carnitin mit dem mikroorganismus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2398046A1 (fr) * 1977-07-18 1979-02-16 Inst Francais Du Petrole Synthese enzymatique de la l-carnitine

Also Published As

Publication number Publication date
GB2078742A (en) 1982-01-13
DE3123975C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-10-11
JPH022591B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-01-18
CH650274A5 (it) 1985-07-15
JPS5739791A (en) 1982-03-05
SE8103851L (sv) 1981-12-25
AT379615B (de) 1986-02-10
ATA276881A (de) 1985-06-15
GB2078742B (en) 1984-01-18
IT1142201B (it) 1986-10-08
SE443803B (sv) 1986-03-10
DE3123975A1 (de) 1982-03-11
US4371618A (en) 1983-02-01
IT8086253A0 (it) 1980-06-24
FR2485564A1 (fr) 1981-12-31

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Legal Events

Date Code Title Description
ST Notification of lapse