FR2479227A1 - Sel de sodium de n-carboxy cephadroxyle - Google Patents
Sel de sodium de n-carboxy cephadroxyle Download PDFInfo
- Publication number
- FR2479227A1 FR2479227A1 FR8106001A FR8106001A FR2479227A1 FR 2479227 A1 FR2479227 A1 FR 2479227A1 FR 8106001 A FR8106001 A FR 8106001A FR 8106001 A FR8106001 A FR 8106001A FR 2479227 A1 FR2479227 A1 FR 2479227A1
- Authority
- FR
- France
- Prior art keywords
- cephadroxyl
- carboxy
- sodium salt
- disodium salt
- acetone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NOJNFULGOQGBKB-UHFFFAOYSA-M sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate Chemical compound [Na+].C1=NC(OCC)=CC=C1C(C=C1)=CC=C1CN1C2=CC=C(OCC=3N=CC(C)=CC=3)C=C2C(SC(C)(C)C)=C1CC(C)(C)C([O-])=O NOJNFULGOQGBKB-UHFFFAOYSA-M 0.000 title 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 230000003115 biocidal effect Effects 0.000 abstract description 4
- 150000003839 salts Chemical class 0.000 abstract description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 12
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 4
- 229910000029 sodium carbonate Inorganic materials 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 238000001816 cooling Methods 0.000 description 2
- 239000002178 crystalline material Substances 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000002906 microbiologic effect Effects 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 150000007514 bases Chemical class 0.000 description 1
- FFGPTBGBLSHEPO-UHFFFAOYSA-N carbamazepine Chemical compound C1=CC2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 FFGPTBGBLSHEPO-UHFFFAOYSA-N 0.000 description 1
- 229960002588 cefradine Drugs 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 150000004682 monohydrates Chemical class 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21096/80A IT1141268B (it) | 1980-04-01 | 1980-04-01 | Sale disodico dell'n-carbossi cefadroxil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2479227A1 true FR2479227A1 (fr) | 1981-10-02 |
| FR2479227B1 FR2479227B1 (enExample) | 1984-02-17 |
Family
ID=11176673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8106001A Granted FR2479227A1 (fr) | 1980-04-01 | 1981-03-25 | Sel de sodium de n-carboxy cephadroxyle |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4380630A (enExample) |
| JP (1) | JPS56152489A (enExample) |
| CA (1) | CA1146541A (enExample) |
| CH (1) | CH646179A5 (enExample) |
| DE (1) | DE3112169A1 (enExample) |
| FR (1) | FR2479227A1 (enExample) |
| GB (1) | GB2073191A (enExample) |
| IL (1) | IL62375A (enExample) |
| IT (1) | IT1141268B (enExample) |
| NL (1) | NL8101273A (enExample) |
| YU (1) | YU84581A (enExample) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2147270A1 (enExample) * | 1971-07-28 | 1973-03-09 | Squibb & Sons Inc |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3489750A (en) * | 1967-09-05 | 1970-01-13 | Bristol Myers Co | 7-amino-cephalosporanic and decephalosporanic acid derivatives |
| US4016158A (en) * | 1971-12-31 | 1977-04-05 | Roussel-Uclaf | Cephalosporin derivatives |
| US3985741A (en) * | 1972-09-15 | 1976-10-12 | Bristol-Myers Company | Production of p-hydroxycephalexin |
-
1980
- 1980-04-01 IT IT21096/80A patent/IT1141268B/it active
-
1981
- 1981-03-04 US US06/240,311 patent/US4380630A/en not_active Expired - Lifetime
- 1981-03-10 CA CA000372704A patent/CA1146541A/en not_active Expired
- 1981-03-13 CH CH173281A patent/CH646179A5/it not_active IP Right Cessation
- 1981-03-16 NL NL8101273A patent/NL8101273A/nl not_active Application Discontinuation
- 1981-03-16 IL IL62375A patent/IL62375A/xx unknown
- 1981-03-25 FR FR8106001A patent/FR2479227A1/fr active Granted
- 1981-03-27 JP JP4421581A patent/JPS56152489A/ja active Pending
- 1981-03-27 DE DE19813112169 patent/DE3112169A1/de not_active Ceased
- 1981-03-31 GB GB8109980A patent/GB2073191A/en not_active Withdrawn
- 1981-03-31 YU YU00845/81A patent/YU84581A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2147270A1 (enExample) * | 1971-07-28 | 1973-03-09 | Squibb & Sons Inc |
Also Published As
| Publication number | Publication date |
|---|---|
| IL62375A (en) | 1983-11-30 |
| CH646179A5 (it) | 1984-11-15 |
| FR2479227B1 (enExample) | 1984-02-17 |
| GB2073191A (en) | 1981-10-14 |
| IT8021096A0 (it) | 1980-04-01 |
| DE3112169A1 (de) | 1982-01-14 |
| CA1146541A (en) | 1983-05-17 |
| YU84581A (en) | 1983-10-31 |
| US4380630A (en) | 1983-04-19 |
| JPS56152489A (en) | 1981-11-26 |
| IL62375A0 (en) | 1981-05-20 |
| IT1141268B (it) | 1986-10-01 |
| NL8101273A (nl) | 1981-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |