FR2475542B1 - - Google Patents

Info

Publication number
FR2475542B1
FR2475542B1 FR8102716A FR8102716A FR2475542B1 FR 2475542 B1 FR2475542 B1 FR 2475542B1 FR 8102716 A FR8102716 A FR 8102716A FR 8102716 A FR8102716 A FR 8102716A FR 2475542 B1 FR2475542 B1 FR 2475542B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8102716A
Other languages
French (fr)
Other versions
FR2475542A1 (en:Method
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK57480A external-priority patent/DK147109C/da
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of FR2475542A1 publication Critical patent/FR2475542A1/fr
Application granted granted Critical
Publication of FR2475542B1 publication Critical patent/FR2475542B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8102716A 1980-02-11 1981-02-11 Expired FR2475542B1 (en:Method)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK57480A DK147109C (da) 1980-02-11 1980-02-11 Fremgangsmaade til fremstilling af humant insulin eller humane insulinestere eller et salt eller kompleks deraf
DK366280 1980-08-28

Publications (2)

Publication Number Publication Date
FR2475542A1 FR2475542A1 (en:Method) 1981-08-14
FR2475542B1 true FR2475542B1 (en:Method) 1988-09-09

Family

ID=26064239

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8102716A Expired FR2475542B1 (en:Method) 1980-02-11 1981-02-11

Country Status (4)

Country Link
US (1) US4343898A (en:Method)
AT (1) AT399881B (en:Method)
FR (1) FR2475542B1 (en:Method)
IE (1) IE50892B1 (en:Method)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
EP0088117B1 (en) * 1981-09-15 1986-09-24 Nordisk Insulinlaboratorium Process for preparing human insulin or b-30 esters thereof
DK353781A (da) * 1981-08-10 1983-02-11 Novo Industri As Fremgangsmaade til fremstilling af insulinderivater
NL8201650A (nl) * 1982-04-21 1983-11-16 Akzo Nv Semisynthetische bereiding van humane insuline.
US4528134A (en) * 1982-12-27 1985-07-09 University Of Tn Research Corporation Method of separating A14 -125 I-insulin from heterogeneously labeled insulin molecules for biological studies
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
US5512459A (en) * 1993-07-20 1996-04-30 Bionebraska, Inc. Enzymatic method for modification or recombinant polypeptides
ID24890A (id) 1997-10-24 2000-08-31 Lilly Co Eli Komposisi-komposisi insulin yang tidak dapat larut
CO4970787A1 (es) 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
DE60044728D1 (de) 1999-12-29 2010-09-02 Novo Nordisk As VERFAHREN ZUR HERSTELLUNG VON INSULINVORLäUFERN UND ANALOGEN VON INSULINVORLÄUFERN MIT VERBESSERTER FERMENTATIONSAUSBEUTE IN HEFE
AR025646A1 (es) * 2000-09-13 2002-12-04 Beta Lab Sa Cepa de levaduras metilotroficas recombinantes productoras de un precursor de insulina, construcciones de adn y metodo para obtener la cepa.
DE60236014D1 (de) 2001-11-19 2010-05-27 Novo Nordisk As Verfahren zur herstellung von insulinverbindungen
US7396903B2 (en) * 2001-11-19 2008-07-08 Novo Nordisk A/S Process for preparing insulin compounds
UA46667C2 (en) * 2001-12-29 2006-01-16 Omakooe Ltd Liability Company Method for preparing semisynthetic human insulin
US20080085298A1 (en) * 2004-03-12 2008-04-10 Biodel, Inc. Rapid Mucosal Gel or Film Insulin Compositions
US20080090753A1 (en) * 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
JP5022213B2 (ja) * 2004-03-12 2012-09-12 バイオデル， インコーポレイテッド 迅速に作用する薬物送達組成物
US20080096800A1 (en) * 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
BRPI0609676A2 (pt) 2005-05-13 2011-10-18 Lilly Co Eli composto de glp-1 peguilado,e, uso do mesmo
WO2007007345A1 (en) * 2005-07-08 2007-01-18 Biocon Limited Preparation of insulin conjugates
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) * 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
CA2649109A1 (en) * 2006-04-12 2007-10-25 Biodel, Inc. Rapid acting and long acting insulin combination formulations
US8288339B2 (en) 2006-04-20 2012-10-16 Amgen Inc. GLP-1 compounds
WO2008124522A2 (en) * 2007-04-04 2008-10-16 Biodel, Inc. Amylin formulations
CA2711561A1 (en) * 2008-01-04 2009-07-16 Biodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
WO2010013762A1 (ja) 2008-07-30 2010-02-04 武田薬品工業株式会社 メタスチン誘導体およびその用途
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
US8618049B2 (en) 2009-09-08 2013-12-31 Stephen B. H. Kent Ester insulin
EP2585483A1 (en) 2010-06-23 2013-05-01 Novo Nordisk A/S Human insulin containing additional disulfide bonds
EP2585484A1 (en) 2010-06-23 2013-05-01 Novo Nordisk A/S Insulin analogues containing additional disulfide bonds
CN104693302A (zh) 2010-06-23 2015-06-10 诺沃—诺迪斯克有限公司 包含额外的二硫键的胰岛素衍生物
US9187547B2 (en) 2011-03-15 2015-11-17 Novo Nordisk A/S Human insulin analogues and derivatives comprising cysteine substitutions
EP2720711A1 (en) 2011-06-15 2014-04-23 Novo Nordisk A/S Multi substituted insulins
JP6735561B2 (ja) 2012-12-03 2020-08-05 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Ｏ−グリコシル化カルボキシ末端部分（ｃｔｐ）ペプチド系のインスリンおよびインスリン類似体
JP2016521701A (ja) 2013-06-07 2016-07-25 ノヴォ ノルディスク アー／エス 成熟インスリンポリペプチドを作製するための方法
US10611813B2 (en) * 2013-12-23 2020-04-07 Biocon Research Limited Method of production of human insulin methyl ester
CN111032685A (zh) 2017-08-17 2020-04-17 诺沃挪第克公司 新型酰化胰岛素类似物及其用途
WO2023144240A1 (en) 2022-01-26 2023-08-03 Novo Nordisk Research Centre Oxford Limited Glucose sensitive insulin derivatives and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin

Also Published As

Publication number Publication date
US4343898A (en) 1982-08-10
AT399881B (de) 1995-08-25
IE810251L (en) 1981-08-11
IE50892B1 (en) 1986-08-06
ATA63681A (de) 1994-12-15
FR2475542A1 (en:Method) 1981-08-14

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Legal Events

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