FR2455603A1 - Nouveaux analogues de thromboxane et medicaments les contenant - Google Patents
Nouveaux analogues de thromboxane et medicaments les contenantInfo
- Publication number
- FR2455603A1 FR2455603A1 FR8009801A FR8009801A FR2455603A1 FR 2455603 A1 FR2455603 A1 FR 2455603A1 FR 8009801 A FR8009801 A FR 8009801A FR 8009801 A FR8009801 A FR 8009801A FR 2455603 A1 FR2455603 A1 FR 2455603A1
- Authority
- FR
- France
- Prior art keywords
- txa
- drugs containing
- methano
- compounds
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 150000003595 thromboxanes Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 108010069102 Thromboxane-A synthase Proteins 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0058—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring
- C07C405/0066—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring to a six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'INVENTION A TRAIT AU DOMAINE DE LA CHIMIE DES MEDICAMENTS. ELLE CONCERNE DE NOUVEAUX COMPOSES DU TYPE 11A-METHANO-TXA ET DES COMPOSES INTERMEDIAIRES PERMETTANT DE LES OBTENIR. LES COMPOSES DU TYPE 11A-METHANO-TXA REPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) LES ANALOGUES DE TXA DE L'INVENTION SONT DES INHIBITEURS DE THROMBOXANE-SYNTHETASE. ILS PEUVENT ETRE UTILISES A DES FINS PHARMACOLOGIQUES COMME ANTI-INFLAMMATOIRES, ANTITHROMBOTIQUES ET ANTI-ASTHMATIQUES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/035,143 US4218378A (en) | 1979-05-01 | 1979-05-01 | 11a-Methano-TXA compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2455603A1 true FR2455603A1 (fr) | 1980-11-28 |
FR2455603B1 FR2455603B1 (fr) | 1983-08-12 |
Family
ID=21880919
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8009801A Granted FR2455603A1 (fr) | 1979-05-01 | 1980-04-30 | Nouveaux analogues de thromboxane et medicaments les contenant |
Country Status (6)
Country | Link |
---|---|
US (1) | US4218378A (fr) |
JP (1) | JPS55162734A (fr) |
DE (1) | DE3016556A1 (fr) |
FR (1) | FR2455603A1 (fr) |
GB (2) | GB2048872B (fr) |
IT (1) | IT8021645A0 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4513103A (en) * | 1983-10-21 | 1985-04-23 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease |
JPH01224381A (ja) * | 1988-03-04 | 1989-09-07 | Japan Tobacco Inc | トリコスタチン酸、トリコスタチンaの新規な合成中間体、及びトリコスタチン酸、トリコスタチンaの製造方法。 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3985798A (en) * | 1975-01-27 | 1976-10-12 | American Cyanamid Company | 11α-HOMO-PROSTANOIC ACIDS AND ESTERS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4107427A (en) * | 1976-08-20 | 1978-08-15 | The Upjohn Company | Process and intermediates for preparing Thromboxane B1 |
-
1979
- 1979-05-01 US US06/035,143 patent/US4218378A/en not_active Expired - Lifetime
-
1980
- 1980-04-24 IT IT8021645A patent/IT8021645A0/it unknown
- 1980-04-25 GB GB8013772A patent/GB2048872B/en not_active Expired
- 1980-04-29 DE DE19803016556 patent/DE3016556A1/de not_active Withdrawn
- 1980-04-30 JP JP5640780A patent/JPS55162734A/ja active Pending
- 1980-04-30 FR FR8009801A patent/FR2455603A1/fr active Granted
-
1982
- 1982-11-04 GB GB08231491A patent/GB2109374B/en not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3985798A (en) * | 1975-01-27 | 1976-10-12 | American Cyanamid Company | 11α-HOMO-PROSTANOIC ACIDS AND ESTERS |
Non-Patent Citations (2)
Title |
---|
EXBK/75 * |
EXBK/79 * |
Also Published As
Publication number | Publication date |
---|---|
US4218378A (en) | 1980-08-19 |
GB2109374A (en) | 1983-06-02 |
JPS55162734A (en) | 1980-12-18 |
IT8021645A0 (it) | 1980-04-24 |
GB2048872B (en) | 1983-05-25 |
GB2048872A (en) | 1980-12-17 |
FR2455603B1 (fr) | 1983-08-12 |
GB2109374B (en) | 1983-09-28 |
DE3016556A1 (de) | 1980-11-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |