FR2449087A2 - Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2449087A2
FR2449087A2 FR7904004A FR7904004A FR2449087A2 FR 2449087 A2 FR2449087 A2 FR 2449087A2 FR 7904004 A FR7904004 A FR 7904004A FR 7904004 A FR7904004 A FR 7904004A FR 2449087 A2 FR2449087 A2 FR 2449087A2
Authority
FR
France
Prior art keywords
amino
antihypertensives
free
low toxicity
imidazolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7904004A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7904004A priority Critical patent/FR2449087A2/fr
Priority to NL7902993A priority patent/NL7902993A/xx
Priority to AU46219/79A priority patent/AU4621979A/en
Priority to GB7913821A priority patent/GB2020280B/en
Priority to NZ190245A priority patent/NZ190245A/xx
Priority to SE7903554A priority patent/SE7903554L/xx
Priority to DK166979A priority patent/DK166979A/da
Priority to LU81182A priority patent/LU81182A1/fr
Priority to ES479878A priority patent/ES479878A1/es
Priority to IT22150/79A priority patent/IT1112581B/it
Priority to DE19792916577 priority patent/DE2916577A1/de
Priority to ES482070A priority patent/ES482070A1/es
Publication of FR2449087A2 publication Critical patent/FR2449087A2/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NOUVEAUX DERIVES DE L'ISOQUINOLEINE DE FORMULE GENERALE I DANS LAQUELLE R REPRESENTE UN ATOME D'HYDROGENE OU UN RADICAL HYDROXYALCOYLE, L'UN DES SYMBOLES R OU R REPRESENTE UN ATOME D'HYDROGENE OU D'HALOGENE OU UN RADICAL ALCOYLE, ALCOYLOXY, ALCOYLOXYALCOYLE, ALCOYLTHIO OU DIALCOYLAMINO ET L'AUTRE REPRESENTE UN RADICAL ALCOYLOXY, ALCOYLOXYALCOYLE, ALCOYLTHIO OU DIALCOYLAMINO, LEURS SELS D'ADDITION AVEC LES ACIDES, LEUR PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT. CES NOUVEAUX DERIVES SONT PARTICULIEREMENT ACTIFS COMME ANTI-HYPERTENSEURS. (CF DESSIN DANS BOPI)
FR7904004A 1978-04-24 1979-02-16 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent Pending FR2449087A2 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR7904004A FR2449087A2 (fr) 1979-02-16 1979-02-16 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent
NL7902993A NL7902993A (nl) 1978-04-24 1979-04-17 Nieuwe isochinolinederivaten, de bereiding ervan en farmaceutische preparaten, die de nieuwe isochinoline- derivaten bevatten.
AU46219/79A AU4621979A (en) 1978-04-24 1979-04-20 Isoquinoline derivatives
GB7913821A GB2020280B (en) 1978-04-24 1979-04-20 4,5-dihydroimidazol-z-yl amino substatuted isoquinolines
NZ190245A NZ190245A (en) 1978-04-24 1979-04-20 Isoquinoline derivatives and pharmaceutical compositions containing them
SE7903554A SE7903554L (sv) 1978-04-24 1979-04-23 Nya derivat av isokinolin, forfaranden for framstellning av desamma och farmaceutiska kompositioner innehallande desamma
DK166979A DK166979A (da) 1978-04-24 1979-04-23 Isoquinderivater fremgangsmaade til deres fremstilling samt farmaceutiske praeparater deraf
LU81182A LU81182A1 (fr) 1978-04-24 1979-04-23 Nouveaux derives de l'isoquinoleine,leur preparation et les compositions pharmaceutiques qui les contiennent
ES479878A ES479878A1 (es) 1978-04-24 1979-04-24 Procedimiento de preparacion de un nuevo derivado de la iso-quinoleina.
IT22150/79A IT1112581B (it) 1978-04-24 1979-04-24 Derivati dell'isochinolina,loro preparazione,e composizioni farmaceutiche che li contengono
DE19792916577 DE2916577A1 (de) 1978-04-24 1979-04-24 Neue derivate des isochinolins, ihre herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen
ES482070A ES482070A1 (es) 1978-04-24 1979-06-29 Procedimiento de preparacion de un nuevo derivado de isoqui-noleina.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7904004A FR2449087A2 (fr) 1979-02-16 1979-02-16 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
FR2449087A2 true FR2449087A2 (fr) 1980-09-12

Family

ID=9222078

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7904004A Pending FR2449087A2 (fr) 1978-04-24 1979-02-16 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent

Country Status (1)

Country Link
FR (1) FR2449087A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1211341A (fr) * 1955-12-19 1960-03-15 A Wander Dr Procédé pour la préparation de 2-amino-imidazolines
NL7302799A (fr) * 1972-02-29 1973-08-31

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1211341A (fr) * 1955-12-19 1960-03-15 A Wander Dr Procédé pour la préparation de 2-amino-imidazolines
NL7302799A (fr) * 1972-02-29 1973-08-31
DE2309160A1 (de) * 1972-02-29 1973-09-27 Pfizer 2-imidazolin-2-yl-amino-substituierte, benzokondensierte, heterocyclische verbindungen und arzneipraeparate
FR2181776A1 (fr) * 1972-02-29 1973-12-07 Pfizer
GB1381979A (en) * 1972-02-29 1975-01-29 Pfizer Ltd Amino derivatives of quinoline quinoxaline and quinazoline
US3890319A (en) * 1972-02-29 1975-06-17 Pfizer (2-imidazolin-2-y(amino) substituted quinolines, -quinoxalines and -quinazolines as antihypertensive agents

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