FR2447377A1 - 25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit - Google Patents

25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit

Info

Publication number
FR2447377A1
FR2447377A1 FR8001685A FR8001685A FR2447377A1 FR 2447377 A1 FR2447377 A1 FR 2447377A1 FR 8001685 A FR8001685 A FR 8001685A FR 8001685 A FR8001685 A FR 8001685A FR 2447377 A1 FR2447377 A1 FR 2447377A1
Authority
FR
France
Prior art keywords
hydroxycholecalciferol
lactone
product
pharmaceutical composition
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8001685A
Other languages
English (en)
Other versions
FR2447377B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of FR2447377A1 publication Critical patent/FR2447377A1/fr
Application granted granted Critical
Publication of FR2447377B1 publication Critical patent/FR2447377B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Abstract

L'INVENTION CONCERNE L'INDUSTRIE PHARMACEUTIQUE. ELLE A POUR OBJET UN NOUVEAU DERIVE DE LA VITAMINE D, A SAVOIR LA 25-HYDROXYCHOLECALCIFEROL-26,23-LACTONE. CE COMPOSE MANIFESTE UNE ACTIVITE VITAMINOIDE D SE TRADUISANT PAR SON APTITUDE A AUGMENTER LA CONCENTRATION EN CALCIUM DU SANG PAR MOBILISATION OSSEUSE. CE COMPOSE EST PREFERE POUR LE TRAITEMENT DES AFFECTIONS EXIGEANT UNE AUGMENTATION DE LA CONCENTRATION EN CALCIUM DU SERUM.
FR8001685A 1979-01-26 1980-01-25 25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit Granted FR2447377A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/007,473 US4223131A (en) 1979-01-26 1979-01-26 25-Hydroxycholecalciferol-26,23-lactone

Publications (2)

Publication Number Publication Date
FR2447377A1 true FR2447377A1 (fr) 1980-08-22
FR2447377B1 FR2447377B1 (fr) 1982-11-19

Family

ID=21726382

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8001685A Granted FR2447377A1 (fr) 1979-01-26 1980-01-25 25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit

Country Status (12)

Country Link
US (1) US4223131A (fr)
JP (1) JPS56500045A (fr)
AU (1) AU529072B2 (fr)
BE (1) BE881358A (fr)
CH (1) CH642071A5 (fr)
FR (1) FR2447377A1 (fr)
GB (1) GB2042549B (fr)
IE (1) IE49369B1 (fr)
IL (1) IL59162A (fr)
NL (1) NL8020035A (fr)
NZ (1) NZ192603A (fr)
WO (1) WO1980001565A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3247836A1 (de) * 1981-12-29 1983-07-07 Teijin Ltd., Osaka Arzneimittel und verwendung derselben zur steuerung der serumcalciumkonzentration bei warmbluetern
JPS58118515A (ja) * 1981-12-29 1983-07-14 Teijin Ltd ２５‐ヒドロキシビタミンｄ↓３―２６，２３‐ラクトンを含有する血清カルシュウム低下剤
US4456689A (en) * 1982-05-17 1984-06-26 Becton Dickinson And Company Competitive protein binding assay using an organosilane-silica gel separation medium

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565924A (en) * 1968-07-01 1971-02-23 Wisconsin Alumni Res Found 25-hydroxycholfcalciferol
US3772150A (en) * 1971-12-29 1973-11-13 Us Health Process for producing vitamin d{11 {11 metabolite
US3715374A (en) * 1972-05-05 1973-02-06 Wisconsin Alumni Res Found 24,25-dihydroxycholecalciferol
US3847955A (en) * 1973-07-16 1974-11-12 Wisconsin Alumni Res Found 1,24,25-trihydroxycholecalciferol
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US4028349A (en) * 1976-03-08 1977-06-07 Hoffmann-La Roche Inc. Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1979 *

Also Published As

Publication number Publication date
JPS56500045A (fr) 1981-01-16
AU529072B2 (en) 1983-05-26
IE49369B1 (en) 1985-09-18
IL59162A (en) 1982-12-31
NL8020035A (nl) 1980-11-28
AU5494880A (en) 1980-07-31
GB2042549A (en) 1980-09-24
NZ192603A (en) 1984-05-31
IE800142L (en) 1980-07-26
IL59162A0 (en) 1980-05-30
CH642071A5 (de) 1984-03-30
WO1980001565A1 (fr) 1980-08-07
FR2447377B1 (fr) 1982-11-19
BE881358A (fr) 1980-05-16
US4223131A (en) 1980-09-16
GB2042549B (en) 1983-02-09

Similar Documents

Publication Publication Date Title
FR2387970A1 (fr) Derives de la guanidine et medicament en contenant
FR2440371A1 (fr) Nouveaux composes azotes heterocycliques, des compositions pharmaceutiques en contenant et des procedes pour les preparer
NL970045I1 (nl) Desulfatohirudinen, werkwijze voor hun bereiding en farmaceutische middelen.
FR2453148A1 (fr) Nouveaux derives arylsulfinyle d'acide acetohydroxamique, leur procede de preparation et leur application en therapeutique
FR2415112A1 (fr) Nouveaux derives spirothienohydantoines et composition pharmaceutique les contenant
PT95343A (pt) Processo para a preparacao de composicoes farmaceuticas contendo doses baixas de um agente anticoagulante oral tal como o warfarin e de um inibidor de plaquetas tal como o acido acetilsalilico,como ingredientes acticovos apropriadas para otratamento e/ou prevencao de doencas cardiacas
FR2446828A1 (fr) N-benzylimidazoles inhibiteurs selectifs de thromboxanne-synthetase, leur procede de production et compositions pharmaceutiques les contenant
NO913684D0 (no) Fremgangsmaate for fremstilling av kalsiumopptaksinhibitorer.
FR2505185B1 (fr) Procede de preparation d'un polysulfate de chondroitine injectable, produit obtenu par ce procede et compositions pharmaceutiques le contenant
FR2452481A1 (fr) 24,24-difluoro-1a,25-dixydroxycholecalciferol et composition pharmaceutique renfermant ce produit
FR2444674A1 (fr) Derives de n-alcynyl-n'-(omega-((thiazolyle eventuellement substitue)-methylthio)-alkyle) de n''-cyanoguanidine et d'ethylene 1,1-diamino-2-substitue, leur procede de production et medicament les contenant
FR2457689A1 (fr) Medicament hypolipemique a base de carnitine
FR2447377A1 (fr) 25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit
FR2434162A1 (fr) Nouveaux derives de 4-amino-2-piperidino-quinazoline, leur procede de production et medicament les contenant
FR2450814A1 (fr) 24,24-difluoro-25-hydroxycholecalciferol et composition pharmaceutique renfermant ce produit
FR2556218B1 (fr) Produit pharmaceutique pour application locale constitue par l'association d'un principe actif medicamenteux-agent enzymatique
FR2433541A1 (fr) Nouveau procede de preparation de certains steroides
FR2453152A1 (fr) Nouveaux derives de prostaglandine et medicament les contenant
FR2419724A1 (fr) Antidote pour le traitement des intoxications aigues des animaux et de la volaille par des pesticides organophosphores
FR2506766A1 (fr) Sel de l-lysine ou de dl-lysine de l'acide 5-(p-chlorobenzoyl)-1,4-dimethylpyrrole-2-acetique, son procede de preparation et composition analgesique le contenant
PT77751A (fr) Procede de preparation de derives benzylideniques soufres et de compositions pharmaceutiques le contenant
FR2354097A1 (fr) Composition therapeutique de derives thiazoliques et sa preparation
BR9302809A (pt) Composto,processo para sua preparacao,processo de purificacao dos compostos,medicmanto,emprego e processo para a preparacao de um agente anti-tumoral
FR2400505A1 (fr) 1-phenylethanolamines anti-inflammatoires, compositions pharmaceutiques en comprenant et procedes pour les produire
ATE58521T1 (de) Lysinsalz der 4-biphenylessigsaeure und es enthaltende augenheilmittel.

Legal Events

Date Code Title Description
ST Notification of lapse