FR2447377A1 - 25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit - Google Patents
25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produitInfo
- Publication number
- FR2447377A1 FR2447377A1 FR8001685A FR8001685A FR2447377A1 FR 2447377 A1 FR2447377 A1 FR 2447377A1 FR 8001685 A FR8001685 A FR 8001685A FR 8001685 A FR8001685 A FR 8001685A FR 2447377 A1 FR2447377 A1 FR 2447377A1
- Authority
- FR
- France
- Prior art keywords
- hydroxycholecalciferol
- lactone
- product
- pharmaceutical composition
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IJNDMZIDDKVXHR-DYEHSFNOSA-N 5-[(2r)-2-[(1r,3as,4e,7ar)-4-[(2z)-2-[(5s)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-1-yl]propyl]-3-hydroxy-3-methyloxolan-2-one Chemical compound C([C@@H](C)[C@@H]1[C@]2(CCCC(/[C@@H]2CC1)=C\C=C\1C(CC[C@H](O)C/1)=C)C)C1CC(C)(O)C(=O)O1 IJNDMZIDDKVXHR-DYEHSFNOSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 2
- 229910052791 calcium Inorganic materials 0.000 abstract 2
- 239000011575 calcium Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/007,473 US4223131A (en) | 1979-01-26 | 1979-01-26 | 25-Hydroxycholecalciferol-26,23-lactone |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2447377A1 true FR2447377A1 (fr) | 1980-08-22 |
FR2447377B1 FR2447377B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-11-19 |
Family
ID=21726382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8001685A Granted FR2447377A1 (fr) | 1979-01-26 | 1980-01-25 | 25-hydroxycholecalciferol-26,23-lactone et composition pharmaceutique renfermant ce produit |
Country Status (12)
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3247836A1 (de) * | 1981-12-29 | 1983-07-07 | Teijin Ltd., Osaka | Arzneimittel und verwendung derselben zur steuerung der serumcalciumkonzentration bei warmbluetern |
JPS58118515A (ja) * | 1981-12-29 | 1983-07-14 | Teijin Ltd | 25‐ヒドロキシビタミンd↓3―26,23‐ラクトンを含有する血清カルシュウム低下剤 |
US4456689A (en) * | 1982-05-17 | 1984-06-26 | Becton Dickinson And Company | Competitive protein binding assay using an organosilane-silica gel separation medium |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3565924A (en) * | 1968-07-01 | 1971-02-23 | Wisconsin Alumni Res Found | 25-hydroxycholfcalciferol |
US3772150A (en) * | 1971-12-29 | 1973-11-13 | Us Health | Process for producing vitamin d{11 {11 metabolite |
US3715374A (en) * | 1972-05-05 | 1973-02-06 | Wisconsin Alumni Res Found | 24,25-dihydroxycholecalciferol |
US3847955A (en) * | 1973-07-16 | 1974-11-12 | Wisconsin Alumni Res Found | 1,24,25-trihydroxycholecalciferol |
US3907843A (en) * | 1974-06-14 | 1975-09-23 | Wisconsin Alumni Res Found | 1{60 -Hydroxyergocalciferol and processes for preparing same |
US4028349A (en) * | 1976-03-08 | 1977-06-07 | Hoffmann-La Roche Inc. | Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof |
-
1979
- 1979-01-26 US US06/007,473 patent/US4223131A/en not_active Expired - Lifetime
-
1980
- 1980-01-14 NZ NZ192603A patent/NZ192603A/en unknown
- 1980-01-17 JP JP50044080A patent/JPS56500045A/ja active Pending
- 1980-01-17 NL NL8020035A patent/NL8020035A/xx not_active Application Discontinuation
- 1980-01-17 CH CH716380A patent/CH642071A5/de not_active IP Right Cessation
- 1980-01-17 WO PCT/US1980/000044 patent/WO1980001565A1/en active Application Filing
- 1980-01-18 IL IL59162A patent/IL59162A/xx unknown
- 1980-01-25 FR FR8001685A patent/FR2447377A1/fr active Granted
- 1980-01-25 BE BE0/199120A patent/BE881358A/fr not_active IP Right Cessation
- 1980-01-25 GB GB8002618A patent/GB2042549B/en not_active Expired
- 1980-01-25 IE IE142/80A patent/IE49369B1/en unknown
- 1980-01-25 AU AU54948/80A patent/AU529072B2/en not_active Ceased
Non-Patent Citations (1)
Title |
---|
CA1979 * |
Also Published As
Publication number | Publication date |
---|---|
AU5494880A (en) | 1980-07-31 |
FR2447377B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-11-19 |
IL59162A (en) | 1982-12-31 |
CH642071A5 (de) | 1984-03-30 |
IE49369B1 (en) | 1985-09-18 |
GB2042549B (en) | 1983-02-09 |
AU529072B2 (en) | 1983-05-26 |
NZ192603A (en) | 1984-05-31 |
IE800142L (en) | 1980-07-26 |
JPS56500045A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-01-16 |
NL8020035A (nl) | 1980-11-28 |
WO1980001565A1 (en) | 1980-08-07 |
US4223131A (en) | 1980-09-16 |
BE881358A (fr) | 1980-05-16 |
GB2042549A (en) | 1980-09-24 |
IL59162A0 (en) | 1980-05-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |