FR2447374A1 - Intermediaires pour la preparation d'analogues de la 2trans-prostaglandine e1 - Google Patents

Intermediaires pour la preparation d'analogues de la 2trans-prostaglandine e1

Info

Publication number
FR2447374A1
FR2447374A1 FR8001501A FR8001501A FR2447374A1 FR 2447374 A1 FR2447374 A1 FR 2447374A1 FR 8001501 A FR8001501 A FR 8001501A FR 8001501 A FR8001501 A FR 8001501A FR 2447374 A1 FR2447374 A1 FR 2447374A1
Authority
FR
France
Prior art keywords
prostaglandin
preparation
2trans
analogs
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8001501A
Other languages
English (en)
Other versions
FR2447374B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP655579A external-priority patent/JPS55100377A/ja
Priority claimed from JP655679A external-priority patent/JPS55100378A/ja
Priority claimed from JP655779A external-priority patent/JPS55100379A/ja
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2447374A1 publication Critical patent/FR2447374A1/fr
Application granted granted Critical
Publication of FR2447374B1 publication Critical patent/FR2447374B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DE NOUVEAUX INTERMEDIAIRES POUR LA PREPARATION D'ANALOGUES DE LA TRANS-PROSTAGLANDINE E. CES INTERMEDIAIRES SONT LES COMPOSES DE LA FORMULE CI-DESSOUS, DANS LAQUELLE Y CO OU CHOR (R H OU PROTECTEUR D'HYDROXY); Z CO OU CHOR (R H OU TETRAHYDROPYRANYLE-2); R FORMYLE OU CHOR; R LIAISON SIMPLE OU ALCOYLENE; R H, ALCOYLE OU ALCOXY, OU CYCLOALCOYLE, CYCLOALCOYLOXY, PHENYLE OU PHENOXY SUBSTITUES OU NON; THP TETRAHYDROPYRANYLE-2. UTILISATION POUR PREPARER, PAR CONDENSATION ET HYDROLYSE EVENTUELLE, DES ANALOGUES DE TRANS-PGE. (CF DESSIN DANS BOPI)
FR8001501A 1979-01-25 1980-01-24 Intermediaires pour la preparation d'analogues de la 2trans-prostaglandine e1 Granted FR2447374A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP655579A JPS55100377A (en) 1979-01-25 1979-01-25 Intermediate for prostaglandim analog and its preparation
JP655679A JPS55100378A (en) 1979-01-25 1979-01-25 Intermediate for prostaglandin analog and its preparation
JP655779A JPS55100379A (en) 1979-01-25 1979-01-25 Preparation of prostaglandin analog and its intermediate

Publications (2)

Publication Number Publication Date
FR2447374A1 true FR2447374A1 (fr) 1980-08-22
FR2447374B1 FR2447374B1 (fr) 1981-12-11

Family

ID=27277218

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8001501A Granted FR2447374A1 (fr) 1979-01-25 1980-01-24 Intermediaires pour la preparation d'analogues de la 2trans-prostaglandine e1

Country Status (9)

Country Link
CA (1) CA1154441A (fr)
CH (1) CH644360A5 (fr)
DK (1) DK165111C (fr)
FR (1) FR2447374A1 (fr)
GB (1) GB2045745B (fr)
HU (1) HU183068B (fr)
IT (1) IT1149877B (fr)
NL (1) NL8000428A (fr)
SE (1) SE452157B (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1416410A (en) * 1972-12-29 1975-12-03 Ono Pharmaceutical Co Prostaglandin anologues
GB1540427A (en) * 1972-12-29 1979-02-14 Ono Pharmaceutical Co Prostaglandin analogues

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1416410A (en) * 1972-12-29 1975-12-03 Ono Pharmaceutical Co Prostaglandin anologues
GB1540427A (en) * 1972-12-29 1979-02-14 Ono Pharmaceutical Co Prostaglandin analogues

Also Published As

Publication number Publication date
SE452157B (sv) 1987-11-16
SE8000545L (sv) 1980-07-26
GB2045745B (en) 1983-08-17
GB2045745A (en) 1980-11-05
IT8019399A0 (it) 1980-01-23
HU183068B (en) 1984-04-28
DK27780A (da) 1980-07-26
CA1154441A (fr) 1983-09-27
CH644360A5 (fr) 1984-07-31
DK165111C (da) 1993-03-01
FR2447374B1 (fr) 1981-12-11
IT1149877B (it) 1986-12-10
NL8000428A (nl) 1980-07-29
DK165111B (da) 1992-10-12

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