FR2439016A1 - Solution stable d'erythromycine - Google Patents

Solution stable d'erythromycine

Info

Publication number
FR2439016A1
FR2439016A1 FR7925929A FR7925929A FR2439016A1 FR 2439016 A1 FR2439016 A1 FR 2439016A1 FR 7925929 A FR7925929 A FR 7925929A FR 7925929 A FR7925929 A FR 7925929A FR 2439016 A1 FR2439016 A1 FR 2439016A1
Authority
FR
France
Prior art keywords
erythromycin
stable solution
sufficient quantity
volume
apres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7925929A
Other languages
English (en)
Other versions
FR2439016B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2439016A1 publication Critical patent/FR2439016A1/fr
Application granted granted Critical
Publication of FR2439016B1 publication Critical patent/FR2439016B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Birds (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'INVENTION CONCERNE UNE COMPOSITION PHARMACEUTIQUE COMPRENANT, PAR ML DE VOLUME FINAL, DE 1 A 100MG D'ERYTHROMYCINE COMME INGREDIENT ACTIF, AINSI QUE LES EXCIPIENTS SUIVANTS: ETHANOL, ACIDE NON TOXIQUE EN QUANTITE SUFFISANTE POUR DONNER UN PH COMPRIS ENTRE 8 ET 10 APRES DILUTION AVEC DE L'EAU, ET PROPYLENEGLYCOL EN QUANTITE SUFFISANTE POUR AMENER LE VOLUME A 1ML. LA SOLUTION OBTENUE EST STABLE PENDANT UNE LONGUE PERIODE DE TEMPS ET EST UTILISEE DANS LE TRAITEMENT DE L'ACNE.
FR7925929A 1978-10-20 1979-10-18 Solution stable d'erythromycine Granted FR2439016A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95315978A 1978-10-20 1978-10-20

Publications (2)

Publication Number Publication Date
FR2439016A1 true FR2439016A1 (fr) 1980-05-16
FR2439016B1 FR2439016B1 (fr) 1983-05-27

Family

ID=25493654

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7925929A Granted FR2439016A1 (fr) 1978-10-20 1979-10-18 Solution stable d'erythromycine

Country Status (13)

Country Link
EP (1) EP0010437B1 (fr)
JP (1) JPS5557519A (fr)
AU (1) AU529422B2 (fr)
BE (1) BE879471A (fr)
CA (1) CA1129772A (fr)
CH (1) CH642544A5 (fr)
DE (1) DE2967163D1 (fr)
FR (1) FR2439016A1 (fr)
GB (1) GB2031728B (fr)
IE (1) IE49086B1 (fr)
LU (1) LU81799A1 (fr)
NZ (1) NZ191847A (fr)
ZA (1) ZA795492B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59104326A (ja) * 1982-12-04 1984-06-16 Toyo Jozo Co Ltd マクロライド抗生物質の安定な経口用製剤および安定化法
AU592629B2 (en) * 1986-01-31 1990-01-18 Whitby Research, Inc. Compositions comprising 1-substituted azacycloalkanes and their uses
US4808411A (en) * 1987-06-05 1989-02-28 Abbott Laboratories Antibiotic-polymer compositions
FI883338A (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Vattenloesningar av doxorubicinhydroklorid.
FI883337A (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Icke-vattenloesningar av doxorubicinhydroklorin.
JPH0737389B2 (ja) * 1989-08-29 1995-04-26 久光製薬株式会社 プロスタグランジンｅ１含有の軟膏剤
DE19549794B4 (de) * 1994-10-26 2009-07-30 Novartis Ag Pharmazeutische Zusammensetzungen
GB2327611B (en) * 1994-10-26 1999-06-02 Novartis Ag Macrolide compositions
US5723447A (en) * 1996-07-02 1998-03-03 Rhone Merieux, Inc. Water miscible erythromycin solutions
US6239112B1 (en) * 1998-07-09 2001-05-29 Merial, Inc. Water miscible macrolide solutions
EP1374855A1 (fr) * 2001-03-30 2004-01-02 Takeda Chemical Industries, Ltd. Solutions medicinales

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378523A1 (fr) * 1977-01-26 1978-08-25 Grupper Charles Medicament pour le traitement de l'acne

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000263A (en) * 1975-05-02 1976-12-28 Westwood Pharmaceuticals, Inc. Erythromycin solution

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378523A1 (fr) * 1977-01-26 1978-08-25 Grupper Charles Medicament pour le traitement de l'acne

Also Published As

Publication number Publication date
IE49086B1 (en) 1985-07-24
JPS5557519A (en) 1980-04-28
LU81799A1 (fr) 1980-01-25
EP0010437A2 (fr) 1980-04-30
EP0010437B1 (fr) 1984-08-08
BE879471A (fr) 1980-04-18
CH642544A5 (fr) 1984-04-30
CA1129772A (fr) 1982-08-17
GB2031728B (en) 1983-02-16
NZ191847A (en) 1982-05-31
GB2031728A (en) 1980-04-30
DE2967163D1 (en) 1984-09-13
FR2439016B1 (fr) 1983-05-27
ZA795492B (en) 1981-05-27
AU529422B2 (en) 1983-06-09
JPH0157097B2 (fr) 1989-12-04
IE791995L (en) 1980-04-20
AU5179079A (en) 1980-04-24
EP0010437A3 (en) 1981-05-13

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