FR2426692A1 - Antibiotiques du type cephalosporine et leur procede de preparation - Google Patents

Antibiotiques du type cephalosporine et leur procede de preparation

Info

Publication number
FR2426692A1
FR2426692A1 FR7913526A FR7913526A FR2426692A1 FR 2426692 A1 FR2426692 A1 FR 2426692A1 FR 7913526 A FR7913526 A FR 7913526A FR 7913526 A FR7913526 A FR 7913526A FR 2426692 A1 FR2426692 A1 FR 2426692A1
Authority
FR
France
Prior art keywords
antibiotics
cephalosporin
preparation process
type antibiotics
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7913526A
Other languages
English (en)
Other versions
FR2426692B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2426692A1 publication Critical patent/FR2426692A1/fr
Application granted granted Critical
Publication of FR2426692B1 publication Critical patent/FR2426692B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'invention concerne des céphalosporines. L'invention a pour objet des composés de la formule 1 dans laquelle R**a et R**b qui peuvent être identiques ou différents représentent chacun un groupe alkyle en C1 -C4 ou bien R**a et R**b forment un groupe cycloalkylidène en C3 -C7 avec l'atome de carbone auquel ils sont attachés. Les composés en question possèdent une activité antibiotique à large spectre, particulièrement efficace contre les entérobactériacées.
FR7913526A 1978-05-26 1979-05-28 Antibiotiques du type cephalosporine et leur procede de preparation Granted FR2426692A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2291078 1978-05-26
GB2291478 1978-05-26

Publications (2)

Publication Number Publication Date
FR2426692A1 true FR2426692A1 (fr) 1979-12-21
FR2426692B1 FR2426692B1 (fr) 1983-01-07

Family

ID=26256188

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7913526A Granted FR2426692A1 (fr) 1978-05-26 1979-05-28 Antibiotiques du type cephalosporine et leur procede de preparation

Country Status (13)

Country Link
AT (1) AT365597B (fr)
AU (1) AU524692B2 (fr)
CA (1) CA1130279A (fr)
CH (1) CH646705A5 (fr)
DE (1) DE2921344A1 (fr)
DK (1) DK217079A (fr)
ES (1) ES480920A1 (fr)
FR (1) FR2426692A1 (fr)
IE (1) IE49174B1 (fr)
IT (1) IT1116187B (fr)
NL (1) NL7904126A (fr)
NZ (1) NZ190556A (fr)
SE (1) SE438508B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465737A1 (fr) * 1979-04-12 1981-03-27 Squibb & Sons Inc 7-(2-(2-amino-4-thiazolyl)-2 - ((1-carboxy-1,1 - dialkyl)alcoxyimino)acetamido)cephem sulfoxydes a action antibacterienne

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465737A1 (fr) * 1979-04-12 1981-03-27 Squibb & Sons Inc 7-(2-(2-amino-4-thiazolyl)-2 - ((1-carboxy-1,1 - dialkyl)alcoxyimino)acetamido)cephem sulfoxydes a action antibacterienne

Also Published As

Publication number Publication date
SE438508B (sv) 1985-04-22
DK217079A (da) 1979-11-27
IT1116187B (it) 1986-02-10
ATA383679A (de) 1981-06-15
NZ190556A (en) 1982-05-25
IE791026L (en) 1979-11-26
AT365597B (de) 1982-01-25
IE49174B1 (en) 1985-08-21
AU4742179A (en) 1979-11-29
IT7949180A0 (it) 1979-05-25
AU524692B2 (en) 1982-09-30
NL7904126A (nl) 1979-11-28
SE7904578L (sv) 1979-11-27
ES480920A1 (es) 1980-02-01
DE2921344A1 (de) 1979-12-06
FR2426692B1 (fr) 1983-01-07
CH646705A5 (en) 1984-12-14
CA1130279A (fr) 1982-08-24

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Legal Events

Date Code Title Description
ST Notification of lapse