FR2426466A1 - Nouveaux antibiotiques du type cephalosporine et leur procede de preparation - Google Patents

Nouveaux antibiotiques du type cephalosporine et leur procede de preparation

Info

Publication number
FR2426466A1
FR2426466A1 FR7913525A FR7913525A FR2426466A1 FR 2426466 A1 FR2426466 A1 FR 2426466A1 FR 7913525 A FR7913525 A FR 7913525A FR 7913525 A FR7913525 A FR 7913525A FR 2426466 A1 FR2426466 A1 FR 2426466A1
Authority
FR
France
Prior art keywords
antibiotics
appropriate
preparation process
group
toxic salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7913525A
Other languages
English (en)
Other versions
FR2426466B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB22912/78A external-priority patent/GB1603989A/en
Priority claimed from GB22909/78A external-priority patent/GB1604722A/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2426466A1 publication Critical patent/FR2426466A1/fr
Application granted granted Critical
Publication of FR2426466B1 publication Critical patent/FR2426466B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des céphalosporines. L'invention a plus particulièrement pour objet des composés de la formule générale I dans laquelle R**a et R** b qui peuvent être identiques ou différents représentent chacun un groupe en C1 -C4 , ou forment ensemble avec l'atome de carbone auquel ils sont attachés un groupe cycloalkylidène en C3 -C7 . Ces composés -sont des antibiotiques à activité à large spectre en particulier contre les organismes Gram-négatifs. L'invention concerne aussi la préparation des composés en question.
FR7913525A 1978-05-26 1979-05-28 Nouveaux antibiotiques du type cephalosporine et leur procede de preparation Granted FR2426466A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB22912/78A GB1603989A (en) 1978-05-26 1978-05-26 7-(2-(2-amino-4-thiazolyl)-2-oxymino-acetamido)-cephem derivatives
GB22909/78A GB1604722A (en) 1978-05-26 1978-05-26 7-(2-(2-amino-4-thiozolyl)-2-oxymino-acetamido)-cephem derivatives

Publications (2)

Publication Number Publication Date
FR2426466A1 true FR2426466A1 (fr) 1979-12-21
FR2426466B1 FR2426466B1 (fr) 1983-02-04

Family

ID=26256187

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7913525A Granted FR2426466A1 (fr) 1978-05-26 1979-05-28 Nouveaux antibiotiques du type cephalosporine et leur procede de preparation

Country Status (9)

Country Link
AU (1) AU524735B2 (fr)
CH (1) CH649297A5 (fr)
DE (1) DE2921369A1 (fr)
FR (1) FR2426466A1 (fr)
IE (1) IE49171B1 (fr)
IT (1) IT1116199B (fr)
NL (1) NL7904125A (fr)
NZ (1) NZ190557A (fr)
SE (1) SE438859B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465737A1 (fr) * 1979-04-12 1981-03-27 Squibb & Sons Inc 7-(2-(2-amino-4-thiazolyl)-2 - ((1-carboxy-1,1 - dialkyl)alcoxyimino)acetamido)cephem sulfoxydes a action antibacterienne

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465737A1 (fr) * 1979-04-12 1981-03-27 Squibb & Sons Inc 7-(2-(2-amino-4-thiazolyl)-2 - ((1-carboxy-1,1 - dialkyl)alcoxyimino)acetamido)cephem sulfoxydes a action antibacterienne

Also Published As

Publication number Publication date
NL7904125A (nl) 1979-11-28
FR2426466B1 (fr) 1983-02-04
NZ190557A (en) 1982-05-25
DE2921369A1 (de) 1979-12-06
AU524735B2 (en) 1982-09-30
AU4742379A (en) 1979-11-29
IT7949175A0 (it) 1979-05-25
IE49171B1 (en) 1985-08-21
SE7904579L (sv) 1979-11-27
IT1116199B (it) 1986-02-10
CH649297A5 (en) 1985-05-15
IE791024L (en) 1979-11-26
SE438859B (sv) 1985-05-13

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Legal Events

Date Code Title Description
ST Notification of lapse