FR2425436A1 - Nouvelles 1,2-dihydro-2h-1,4-benzodiazepine - 2 - ones 1,5-disubstituees, utiles notamment comme agents antianxiete et leur procede de preparation - Google Patents
Nouvelles 1,2-dihydro-2h-1,4-benzodiazepine - 2 - ones 1,5-disubstituees, utiles notamment comme agents antianxiete et leur procede de preparationInfo
- Publication number
- FR2425436A1 FR2425436A1 FR7912095A FR7912095A FR2425436A1 FR 2425436 A1 FR2425436 A1 FR 2425436A1 FR 7912095 A FR7912095 A FR 7912095A FR 7912095 A FR7912095 A FR 7912095A FR 2425436 A1 FR2425436 A1 FR 2425436A1
- Authority
- FR
- France
- Prior art keywords
- agents
- antianxiet
- benzodiazepine
- dihydro
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LES MEDICAMENTS SELON L'INVENTION SONT DES COMPOSES DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE: R REPRESENTE UN ATOME D'HYDROGENE OU DE FLUOR, R REPRESENTE UN ATOME D'HYDROGENE, DE FLUOR, DE BROME OU DE CHLORE OU UN GROUPE TRIFLUOROMETHYLE ET N EST EGAL A 2, 3 OU 4, ET LEURS SELS D'ADDITION D'ACIDES. APPLICATIONS: COMME AGENTS ANTIANXIETE, SOUS FORME DE SOLUTIONS, EMULSIONS, SUSPENSIONS, PILULES, TABLETTES ET CAPSULES EN DOSES UNITAIRES DE 5 A 50MG, A DES DOSES JOURNALIERES DE 10 A 100 MG.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/905,268 US4151285A (en) | 1978-05-12 | 1978-05-12 | 1,5-Disubstituted-1,2-dihydro-2H-1,4-benzodiazepin-2-ones |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2425436A1 true FR2425436A1 (fr) | 1979-12-07 |
FR2425436B1 FR2425436B1 (fr) | 1983-06-24 |
Family
ID=25420521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7912095A Granted FR2425436A1 (fr) | 1978-05-12 | 1979-05-11 | Nouvelles 1,2-dihydro-2h-1,4-benzodiazepine - 2 - ones 1,5-disubstituees, utiles notamment comme agents antianxiete et leur procede de preparation |
Country Status (8)
Country | Link |
---|---|
US (1) | US4151285A (fr) |
JP (1) | JPS5511567A (fr) |
CA (1) | CA1105460A (fr) |
CH (1) | CH639971A5 (fr) |
DE (1) | DE2918904A1 (fr) |
FR (1) | FR2425436A1 (fr) |
GB (1) | GB2021578B (fr) |
SE (1) | SE439160B (fr) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3542769A (en) * | 1968-08-15 | 1970-11-24 | Smithkline Corp | 1-(4 - substituted piperidinylalkyl) - 5-phenyl-dihydro - 1,4-benzodiazepines and benzodiazepin-2-ones |
US3641002A (en) * | 1968-06-13 | 1972-02-08 | Sumitomo Chemical Co | Benzodiazepine derivatives and salts thereof |
-
1978
- 1978-05-12 US US05/905,268 patent/US4151285A/en not_active Expired - Lifetime
-
1979
- 1979-05-08 CH CH432279A patent/CH639971A5/fr not_active IP Right Cessation
- 1979-05-09 JP JP5685779A patent/JPS5511567A/ja active Pending
- 1979-05-10 DE DE19792918904 patent/DE2918904A1/de not_active Withdrawn
- 1979-05-10 GB GB7916330A patent/GB2021578B/en not_active Expired
- 1979-05-11 SE SE7904162A patent/SE439160B/sv not_active IP Right Cessation
- 1979-05-11 FR FR7912095A patent/FR2425436A1/fr active Granted
- 1979-05-11 CA CA327,437A patent/CA1105460A/fr not_active Expired
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3641002A (en) * | 1968-06-13 | 1972-02-08 | Sumitomo Chemical Co | Benzodiazepine derivatives and salts thereof |
US3542769A (en) * | 1968-08-15 | 1970-11-24 | Smithkline Corp | 1-(4 - substituted piperidinylalkyl) - 5-phenyl-dihydro - 1,4-benzodiazepines and benzodiazepin-2-ones |
Also Published As
Publication number | Publication date |
---|---|
SE7904162L (sv) | 1979-11-13 |
DE2918904A1 (de) | 1979-11-15 |
JPS5511567A (en) | 1980-01-26 |
GB2021578A (en) | 1979-12-05 |
SE439160B (sv) | 1985-06-03 |
FR2425436B1 (fr) | 1983-06-24 |
GB2021578B (en) | 1982-08-04 |
CH639971A5 (fr) | 1983-12-15 |
CA1105460A (fr) | 1981-07-21 |
US4151285A (en) | 1979-04-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |