FR2419286A2 - Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments - Google Patents

Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments

Info

Publication number
FR2419286A2
FR2419286A2 FR7905753A FR7905753A FR2419286A2 FR 2419286 A2 FR2419286 A2 FR 2419286A2 FR 7905753 A FR7905753 A FR 7905753A FR 7905753 A FR7905753 A FR 7905753A FR 2419286 A2 FR2419286 A2 FR 2419286A2
Authority
FR
France
Prior art keywords
preparation
derivatives
isoquinoleine
new
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7905753A
Other languages
English (en)
Other versions
FR2419286B1 (fr
Inventor
Paul Pfaeffli
Hartmut Hauth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH264378A external-priority patent/CH636859A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2419286A2 publication Critical patent/FR2419286A2/fr
Application granted granted Critical
Publication of FR2419286B1 publication Critical patent/FR2419286B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des dérivés de l'isoquinoléine et leur préparation. Les composés répondent à la formule :
FR7905753A 1978-03-10 1979-03-06 Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments Granted FR2419286A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH264378A CH636859A5 (en) 1978-03-10 1978-03-10 Substituted cis-4a-phenyldecahydroisoquinolines, their preparation and drugs containing them
CH628378 1978-06-08

Publications (2)

Publication Number Publication Date
FR2419286A2 true FR2419286A2 (fr) 1979-10-05
FR2419286B1 FR2419286B1 (fr) 1982-03-05

Family

ID=25691019

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7905753A Granted FR2419286A2 (fr) 1978-03-10 1979-03-06 Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments

Country Status (15)

Country Link
JP (1) JPS54128585A (fr)
AU (1) AU529350B2 (fr)
CA (1) CA1118775A (fr)
DE (1) DE2907461A1 (fr)
DK (1) DK88279A (fr)
ES (1) ES478430A1 (fr)
FI (1) FI790701A (fr)
FR (1) FR2419286A2 (fr)
GB (1) GB2016012B (fr)
IL (1) IL56823A0 (fr)
IT (1) IT7948220A0 (fr)
NL (1) NL7901764A (fr)
NZ (1) NZ189856A (fr)
PH (1) PH14162A (fr)
SE (1) SE7901848L (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2600649B1 (fr) * 1986-06-26 1989-02-24 Rhone Poulenc Sante Procede de preparation du maleate acide de levomepromazine
DE69602248T4 (de) * 1995-07-20 2000-10-26 Toray Industries, Inc. 4a-aryldecahydroisochinolin-verbindungen und ihre medizinische verwendungen
ES2780699T3 (es) * 2013-07-10 2020-08-26 Vertex Pharma Amidas de piperidina fusionadas útiles como moduladores de canales iónicos

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2335225A1 (fr) * 1975-12-16 1977-07-15 Sandoz Sa Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2335225A1 (fr) * 1975-12-16 1977-07-15 Sandoz Sa Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments

Also Published As

Publication number Publication date
ES478430A1 (es) 1979-05-16
GB2016012A (en) 1979-09-19
CA1118775A (fr) 1982-02-23
SE7901848L (sv) 1979-09-11
AU4495679A (en) 1979-09-13
NZ189856A (en) 1981-12-15
JPS54128585A (en) 1979-10-05
FR2419286B1 (fr) 1982-03-05
GB2016012B (en) 1982-07-21
PH14162A (en) 1981-03-19
IL56823A0 (en) 1979-05-31
NL7901764A (nl) 1979-09-12
AU529350B2 (en) 1983-06-02
FI790701A (fi) 1979-09-11
DK88279A (da) 1979-09-11
DE2907461A1 (de) 1979-09-20
IT7948220A0 (it) 1979-03-06

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Legal Events

Date Code Title Description
ST Notification of lapse