GB2016012B - Pharmaceutically active decahydro-isoquinoline derivatives - Google Patents

Pharmaceutically active decahydro-isoquinoline derivatives

Info

Publication number
GB2016012B
GB2016012B GB7907868A GB7907868A GB2016012B GB 2016012 B GB2016012 B GB 2016012B GB 7907868 A GB7907868 A GB 7907868A GB 7907868 A GB7907868 A GB 7907868A GB 2016012 B GB2016012 B GB 2016012B
Authority
GB
United Kingdom
Prior art keywords
decahydro
pharmaceutically active
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7907868A
Other versions
GB2016012A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH264378A external-priority patent/CH636859A5/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB2016012A publication Critical patent/GB2016012A/en
Application granted granted Critical
Publication of GB2016012B publication Critical patent/GB2016012B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
GB7907868A 1978-03-10 1979-03-06 Pharmaceutically active decahydro-isoquinoline derivatives Expired GB2016012B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH264378A CH636859A5 (en) 1978-03-10 1978-03-10 Substituted cis-4a-phenyldecahydroisoquinolines, their preparation and drugs containing them
CH628378 1978-06-08

Publications (2)

Publication Number Publication Date
GB2016012A GB2016012A (en) 1979-09-19
GB2016012B true GB2016012B (en) 1982-07-21

Family

ID=25691019

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7907868A Expired GB2016012B (en) 1978-03-10 1979-03-06 Pharmaceutically active decahydro-isoquinoline derivatives

Country Status (15)

Country Link
JP (1) JPS54128585A (en)
AU (1) AU529350B2 (en)
CA (1) CA1118775A (en)
DE (1) DE2907461A1 (en)
DK (1) DK88279A (en)
ES (1) ES478430A1 (en)
FI (1) FI790701A (en)
FR (1) FR2419286A2 (en)
GB (1) GB2016012B (en)
IL (1) IL56823A0 (en)
IT (1) IT7948220A0 (en)
NL (1) NL7901764A (en)
NZ (1) NZ189856A (en)
PH (1) PH14162A (en)
SE (1) SE7901848L (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2600649B1 (en) * 1986-06-26 1989-02-24 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF LEVOMEPROMAZINE ACID MALEATE
EP0787721B1 (en) * 1995-07-20 1999-04-28 Toray Industries, Inc. 4a-ARYLDECAHYDROISOQUINOLINE COMPOUNDS AND MEDICINAL USES THEREOF
ES2780699T3 (en) * 2013-07-10 2020-08-26 Vertex Pharma Fused piperidine amides useful as ion channel modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2655150A1 (en) * 1975-12-16 1977-06-23 Sandoz Ag NEW ORGANIC COMPOUNDS, THEIR PRODUCTION AND USE

Also Published As

Publication number Publication date
SE7901848L (en) 1979-09-11
DE2907461A1 (en) 1979-09-20
FI790701A (en) 1979-09-11
AU4495679A (en) 1979-09-13
NL7901764A (en) 1979-09-12
JPS54128585A (en) 1979-10-05
PH14162A (en) 1981-03-19
CA1118775A (en) 1982-02-23
AU529350B2 (en) 1983-06-02
ES478430A1 (en) 1979-05-16
GB2016012A (en) 1979-09-19
IT7948220A0 (en) 1979-03-06
DK88279A (en) 1979-09-11
NZ189856A (en) 1981-12-15
FR2419286A2 (en) 1979-10-05
IL56823A0 (en) 1979-05-31
FR2419286B1 (en) 1982-03-05

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee