FR2412560A1 - Nouveaux derives de la fortimicine a et procede pour les preparer - Google Patents

Nouveaux derives de la fortimicine a et procede pour les preparer

Info

Publication number
FR2412560A1
FR2412560A1 FR7835879A FR7835879A FR2412560A1 FR 2412560 A1 FR2412560 A1 FR 2412560A1 FR 7835879 A FR7835879 A FR 7835879A FR 7835879 A FR7835879 A FR 7835879A FR 2412560 A1 FR2412560 A1 FR 2412560A1
Authority
FR
France
Prior art keywords
fortimicin
preparing
group
new derivatives
hydroxyalkinkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7835879A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of FR2412560A1 publication Critical patent/FR2412560A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

NOUVEAUX DERIVES DE LA FORTIMICINE A ET PROCEDE POUR LES PREPARER. CES COMPOSES 2-N-SUBSTITUES DE LA FORTIMICINE CORRESPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) (CF DESSIN DANS BOPI) OU R EST H OU FORME AVEC N ET R UN GROUPEMENT 2-PYRROLIDONYLE SUBSTITUE OU NON, ET R EST -COR, -CHR, -CH(R) OU AMIDINO, R ETANT UN GROUPE AMINO, HYDROXYAMINO-ALKYLE OU CARBAMOYLAMINOALKYLE ET R EST UN GROUPE DIAMINOALKYLE, HYDROXYALKYLE, DIHYDROXYALKYLE, HYDROXYAMINO-ALKYLE OU GUANIDINOALKYLE. UTILISATION DE CES DERIVES COMME MEDICAMENTS POUR LES VOIES URINAIRES, ET RESPIRATOIRES ET LES ETATS SEPTIQUES DUS AUX MICRO-ORGANISMES RESISTANT A DE NOMBREUX ANTIBIOTIQUES.
FR7835879A 1977-12-21 1978-12-21 Nouveaux derives de la fortimicine a et procede pour les preparer Withdrawn FR2412560A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15300177A JPS5488241A (en) 1977-12-21 1977-12-21 Novel fortimicin a derivative

Publications (1)

Publication Number Publication Date
FR2412560A1 true FR2412560A1 (fr) 1979-07-20

Family

ID=15552771

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7835879A Withdrawn FR2412560A1 (fr) 1977-12-21 1978-12-21 Nouveaux derives de la fortimicine a et procede pour les preparer

Country Status (5)

Country Link
US (1) US4237272A (fr)
JP (1) JPS5488241A (fr)
DE (1) DE2855348A1 (fr)
FR (1) FR2412560A1 (fr)
GB (1) GB2011893A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2412559A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine a et leurs procedes de preparation
FR2412561A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine b, leur procede de preparation et leur utilisation comme medicament
WO1982000464A1 (fr) * 1980-07-28 1982-02-18 Loibner H Aminoglycosides guanyles, leur procede de preparation et leur utilisation comme produits pharmaceutiques

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256876A (en) * 1980-02-04 1981-03-17 The Upjohn Company Process for precipitating aminoglycosides
GB9905771D0 (en) * 1999-03-12 1999-05-05 Isis Innovation Compounds
US20060228308A1 (en) * 2004-02-26 2006-10-12 Cummins Barry W Oral health care drink and method for reducing malodors
US8067415B2 (en) * 2005-11-01 2011-11-29 Millennium Pharmaceuticals, Inc. Compounds useful as antagonists of CCR2
US20100016289A1 (en) * 2005-11-01 2010-01-21 Kevin Sprott Compounds Useful as Antagonists of CCR2
US8067457B2 (en) * 2005-11-01 2011-11-29 Millennium Pharmaceuticals, Inc. Compounds useful as antagonists of CCR2

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2412566A1 (fr) * 1977-12-21 1979-07-20 Abbott Lab Nouvelles fortimicines b 2'-n-substituees, utiles notamment comme antibiotiques
FR2412559A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine a et leurs procedes de preparation
FR2412561A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine b, leur procede de preparation et leur utilisation comme medicament

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5145675B2 (fr) * 1973-07-23 1976-12-04
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
DE2644911C3 (de) * 1974-10-26 1979-08-23 Pfizer Corp., Colon (Panama) Derivate von Kanamycin A oder B, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
GB1464401A (en) * 1974-10-26 1977-02-16 Pfizer Ltd Aminoglycosides
US4124756A (en) * 1976-12-27 1978-11-07 Abbott Laboratories 3-DE-O-Methylfortimicins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2412566A1 (fr) * 1977-12-21 1979-07-20 Abbott Lab Nouvelles fortimicines b 2'-n-substituees, utiles notamment comme antibiotiques
FR2412559A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine a et leurs procedes de preparation
FR2412561A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine b, leur procede de preparation et leur utilisation comme medicament

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/77 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2412559A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine a et leurs procedes de preparation
FR2412561A1 (fr) * 1977-12-21 1979-07-20 Kyowa Hakko Kogyo Kk Nouveaux derives de la fortimicine b, leur procede de preparation et leur utilisation comme medicament
WO1982000464A1 (fr) * 1980-07-28 1982-02-18 Loibner H Aminoglycosides guanyles, leur procede de preparation et leur utilisation comme produits pharmaceutiques

Also Published As

Publication number Publication date
DE2855348A1 (de) 1979-07-05
GB2011893A (en) 1979-07-18
US4237272A (en) 1980-12-02
JPS5488241A (en) 1979-07-13

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Legal Events

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