FR2409755A1 - MEDICINES BASED ON NEW INDOLO (2,3-A) QUINOLIZIDINES - Google Patents

MEDICINES BASED ON NEW INDOLO (2,3-A) QUINOLIZIDINES

Info

Publication number
FR2409755A1
FR2409755A1 FR7833176A FR7833176A FR2409755A1 FR 2409755 A1 FR2409755 A1 FR 2409755A1 FR 7833176 A FR7833176 A FR 7833176A FR 7833176 A FR7833176 A FR 7833176A FR 2409755 A1 FR2409755 A1 FR 2409755A1
Authority
FR
France
Prior art keywords
quinolizidines
indolo
new
medicines based
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7833176A
Other languages
French (fr)
Other versions
FR2409755B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2409755A1 publication Critical patent/FR2409755A1/en
Application granted granted Critical
Publication of FR2409755B1 publication Critical patent/FR2409755B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

New indolo (2, 3-a) quinolizidines having the following formulae (I) and (II) (FORMULA) wherein R is a radical -COOC<u2>uH<u5>u, -COOH, -CN, a primary or secondary methylenamino radical, a group methylenamido or, with the nitrogen of the indolo nucleus, a group N-CO-NH-CH<u2>u or N-CO-, as well as the salts of acid addition, therapeutically acceptable of these bodies. Also, a process for preparing the compounds.
FR7833176A 1977-11-25 1978-11-24 MEDICINES BASED ON NEW INDOLO (2,3-A) QUINOLIZIDINES Granted FR2409755A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4920177 1977-11-25

Publications (2)

Publication Number Publication Date
FR2409755A1 true FR2409755A1 (en) 1979-06-22
FR2409755B1 FR2409755B1 (en) 1980-08-01

Family

ID=10451538

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7833175A Granted FR2423492A1 (en) 1977-11-25 1978-11-24 NEW INDOLO (2,3-A) -QUINOLIZIDINES AND THEIR METHODS OF PREPARATION
FR7833176A Granted FR2409755A1 (en) 1977-11-25 1978-11-24 MEDICINES BASED ON NEW INDOLO (2,3-A) QUINOLIZIDINES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7833175A Granted FR2423492A1 (en) 1977-11-25 1978-11-24 NEW INDOLO (2,3-A) -QUINOLIZIDINES AND THEIR METHODS OF PREPARATION

Country Status (28)

Country Link
JP (1) JPS6147838B2 (en)
AR (1) AR218514A1 (en)
AT (1) AT372384B (en)
AU (1) AU529108B2 (en)
BE (1) BE872134A (en)
CA (1) CA1100959A (en)
CH (1) CH641181A5 (en)
DE (1) DE2851028A1 (en)
DK (1) DK154430C (en)
EG (1) EG13683A (en)
ES (1) ES475328A1 (en)
FI (1) FI64372C (en)
FR (2) FR2423492A1 (en)
HK (1) HK60884A (en)
IE (1) IE47518B1 (en)
IN (1) IN151146B (en)
IT (1) IT1160263B (en)
LU (1) LU80576A1 (en)
MX (1) MX5529E (en)
MY (1) MY8500029A (en)
NL (1) NL7811562A (en)
NO (1) NO151288C (en)
NZ (1) NZ188974A (en)
PT (1) PT68825A (en)
SE (2) SE431650B (en)
SG (1) SG61182G (en)
WO (1) WO1979000319A1 (en)
ZA (1) ZA786426B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1532391B2 (en) † 2002-06-24 2019-03-06 Saint-Gobain Isover Insulation panel for supply duct

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3175900D1 (en) * 1981-11-18 1987-03-12 Thal Claude Indoloquinolizine derivatives, process for their preparation and their therapeutic use
FR2529552B1 (en) * 1982-07-05 1985-09-27 Centre Nat Rech Scient NOVEL PROCESS FOR THE PREPARATION OF VINDOLINE SYNTHESIS INTERMEDIATES AND SYNTHESIS INTERMEDIATES
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
FI95572C (en) 1987-06-22 1996-02-26 Eisai Co Ltd Process for the preparation of a medicament useful as a piperidine derivative or its pharmaceutical salt
DK0704439T3 (en) * 1993-06-18 2001-10-08 Fujisawa Pharmaceutical Co Hitherto unknown intermediate for synthetic application and process for the preparation of aminopiperazine derivatives
FR2713644B1 (en) * 1993-12-14 1996-02-09 Adir New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them.
FR2713643B1 (en) * 1993-12-14 1996-06-07 Adir New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them.
FR2911141B1 (en) * 2007-01-05 2009-02-20 Servier Lab NOVEL TRIAZABENZO [A] NAPHTHO [2,1,8-CDE] AZULENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2911143A1 (en) * 2007-01-05 2008-07-11 Servier Lab Use of neuroprotective compounds to prepare medicaments for treating neurodegenerative diseases
FR2911142A1 (en) * 2007-01-05 2008-07-11 Servier Lab New amino-pyrroloindole and amino-pyridazinoindole derivatives, are tyrosine hydroxylase inducers, useful e.g. for treating anxiety, depression or memory loss

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167366B (en) * 1972-09-06 1975-09-27
BE802387A (en) * 1973-07-16 1973-11-16 Omnium Chimique Sa PROCESS FOR PREPARING VINCAMONE AND EPI-21 VINCAMONE FROM TABERSONIN AND NEW INDOLIC DERIVATIVES.
HU169916B (en) * 1974-09-27 1977-02-28
HU171165B (en) * 1974-11-26 1977-11-28 Richter Gedeon Vegyeszet Process for producing oktahydro-indolo-bracket-2,3-a-bracket closed-quinolizine derivatives
FR2315277A1 (en) * 1975-06-25 1977-01-21 Anvar NEW PENTACYCLIC DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1532391B2 (en) † 2002-06-24 2019-03-06 Saint-Gobain Isover Insulation panel for supply duct

Also Published As

Publication number Publication date
DK524978A (en) 1979-05-26
FR2409755B1 (en) 1980-08-01
CA1100959A (en) 1981-05-12
AU529108B2 (en) 1983-05-26
LU80576A1 (en) 1979-03-22
HK60884A (en) 1984-08-10
FI64372C (en) 1983-11-10
JPS54500053A (en) 1979-11-08
SE8007845L (en) 1980-11-07
DE2851028C2 (en) 1990-05-03
NL7811562A (en) 1979-05-29
IE47518B1 (en) 1984-04-04
NO783958L (en) 1979-05-28
BE872134A (en) 1979-03-16
DE2851028A1 (en) 1979-05-31
ZA786426B (en) 1979-10-31
CH641181A5 (en) 1984-02-15
IE782328L (en) 1979-05-25
FR2423492B1 (en) 1980-12-05
AR218514A1 (en) 1980-06-13
AT372384B (en) 1983-09-26
JPS6147838B2 (en) 1986-10-21
MX5529E (en) 1983-09-23
SE435622B (en) 1984-10-08
NO151288C (en) 1985-03-13
SE7906287L (en) 1979-07-23
SE431650B (en) 1984-02-20
IN151146B (en) 1983-02-26
IT1160263B (en) 1987-03-11
FR2423492A1 (en) 1979-11-16
ATA837478A (en) 1983-02-15
PT68825A (en) 1978-12-01
ES475328A1 (en) 1979-04-01
FI783581A (en) 1979-05-26
WO1979000319A1 (en) 1979-06-14
DK154430B (en) 1988-11-14
IT7830171A0 (en) 1978-11-24
MY8500029A (en) 1985-12-31
NO151288B (en) 1984-12-03
NZ188974A (en) 1989-10-27
DK154430C (en) 1989-04-17
SG61182G (en) 1985-02-15
EG13683A (en) 1982-09-30
AU4187478A (en) 1979-05-31
FI64372B (en) 1983-07-29

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Legal Events

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CD Change of name or company name
CN Change in juridical nature
ST Notification of lapse