FR2398733A1 - Nouveau procede de preparation de la glafenine - Google Patents

Nouveau procede de preparation de la glafenine

Info

Publication number
FR2398733A1
FR2398733A1 FR7722900A FR7722900A FR2398733A1 FR 2398733 A1 FR2398733 A1 FR 2398733A1 FR 7722900 A FR7722900 A FR 7722900A FR 7722900 A FR7722900 A FR 7722900A FR 2398733 A1 FR2398733 A1 FR 2398733A1
Authority
FR
France
Prior art keywords
glafenin
preparing
new process
quinoline
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7722900A
Other languages
English (en)
Other versions
FR2398733B1 (fr
Inventor
Sylvano Casadio
Henri Cousse
Pierre Hascoet
Gilbert Moulin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Priority to FR7722900A priority Critical patent/FR2398733A1/fr
Priority to EP78400060A priority patent/EP0000679B1/fr
Priority to DE7878400060T priority patent/DE2860803D1/de
Priority to CA307,785A priority patent/CA1107737A/fr
Priority to JP9031478A priority patent/JPS5424881A/ja
Priority to IT50438/78A priority patent/IT1156878B/it
Priority to ES472072A priority patent/ES472072A1/es
Publication of FR2398733A1 publication Critical patent/FR2398733A1/fr
Application granted granted Critical
Publication of FR2398733B1 publication Critical patent/FR2398733B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

La présente invention concerne la préparation de glafénine. Il s'agit d'un procédé de préparation de l' alpha -monoglycéride de 4(2'-carboxyphénylamino)-7-chloro-quinoléine, caractérisé en ce que l'on condense l'anthranilate de glycéryle avec la 4,7dichloro-quinoléine et en ce que l'on récupère le produit désiré Le produit obtenu est un agent antalgique connu.
FR7722900A 1977-07-26 1977-07-26 Nouveau procede de preparation de la glafenine Granted FR2398733A1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR7722900A FR2398733A1 (fr) 1977-07-26 1977-07-26 Nouveau procede de preparation de la glafenine
EP78400060A EP0000679B1 (fr) 1977-07-26 1978-07-18 Nouveau procédé de préparation de la glafénine
DE7878400060T DE2860803D1 (en) 1977-07-26 1978-07-18 Process for the preparation of glafenine
CA307,785A CA1107737A (fr) 1977-07-26 1978-07-20 Procede de preparation de la glafenine
JP9031478A JPS5424881A (en) 1977-07-26 1978-07-24 Preparing of graphenine
IT50438/78A IT1156878B (it) 1977-07-26 1978-07-24 Procedimento per preparare la glafenina
ES472072A ES472072A1 (es) 1977-07-26 1978-07-26 Procedimiento de preparacion del alfa-manoglicerido de 4(2- carboxifenilamino)-7-cloro-guinoleina.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7722900A FR2398733A1 (fr) 1977-07-26 1977-07-26 Nouveau procede de preparation de la glafenine

Publications (2)

Publication Number Publication Date
FR2398733A1 true FR2398733A1 (fr) 1979-02-23
FR2398733B1 FR2398733B1 (fr) 1980-02-29

Family

ID=9193813

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7722900A Granted FR2398733A1 (fr) 1977-07-26 1977-07-26 Nouveau procede de preparation de la glafenine

Country Status (7)

Country Link
EP (1) EP0000679B1 (fr)
JP (1) JPS5424881A (fr)
CA (1) CA1107737A (fr)
DE (1) DE2860803D1 (fr)
ES (1) ES472072A1 (fr)
FR (1) FR2398733A1 (fr)
IT (1) IT1156878B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549830B1 (fr) * 1983-07-25 1987-04-30 Corbiere Jerome Nouveau procede d'obtention de quinoleines substituees

Also Published As

Publication number Publication date
CA1107737A (fr) 1981-08-25
DE2860803D1 (en) 1981-10-01
IT1156878B (it) 1987-02-04
EP0000679B1 (fr) 1981-06-24
IT7850438A0 (it) 1978-07-24
EP0000679A1 (fr) 1979-02-07
FR2398733B1 (fr) 1980-02-29
ES472072A1 (es) 1979-03-16
JPS5424881A (en) 1979-02-24

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Legal Events

Date Code Title Description
ST Notification of lapse