FR2389626A1 - - Google Patents

Info

Publication number
FR2389626A1
FR2389626A1 FR7813129A FR7813129A FR2389626A1 FR 2389626 A1 FR2389626 A1 FR 2389626A1 FR 7813129 A FR7813129 A FR 7813129A FR 7813129 A FR7813129 A FR 7813129A FR 2389626 A1 FR2389626 A1 FR 2389626A1
Authority
FR
France
Prior art keywords
thienamycin
alkyl
compounds
represented
structural formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7813129A
Other languages
English (en)
French (fr)
Other versions
FR2389626B1 (fi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2389626A1 publication Critical patent/FR2389626A1/fr
Application granted granted Critical
Publication of FR2389626B1 publication Critical patent/FR2389626B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7813129A 1977-05-05 1978-05-03 Expired FR2389626B1 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79397577A 1977-05-05 1977-05-05

Publications (2)

Publication Number Publication Date
FR2389626A1 true FR2389626A1 (fi) 1978-12-01
FR2389626B1 FR2389626B1 (fi) 1980-06-20

Family

ID=25161306

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7813129A Expired FR2389626B1 (fi) 1977-05-05 1978-05-03

Country Status (13)

Country Link
JP (1) JPS53137993A (fi)
BE (1) BE866661A (fi)
CH (1) CH637962A5 (fi)
DE (1) DE2819453A1 (fi)
DK (1) DK170778A (fi)
ES (1) ES469426A1 (fi)
FR (1) FR2389626B1 (fi)
GB (1) GB1604275A (fi)
IE (1) IE46873B1 (fi)
IT (1) IT1104190B (fi)
LU (1) LU79598A1 (fi)
NL (1) NL7804229A (fi)
SE (1) SE436569B (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2332012A1 (fr) * 1975-11-21 1977-06-17 Merck & Co Inc Derives n-methylene substitues de thienamycine utiles comme antibiotiques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2332012A1 (fr) * 1975-11-21 1977-06-17 Merck & Co Inc Derives n-methylene substitues de thienamycine utiles comme antibiotiques

Also Published As

Publication number Publication date
GB1604275A (en) 1981-12-09
DK170778A (da) 1979-01-15
FR2389626B1 (fi) 1980-06-20
ES469426A1 (es) 1980-02-01
BE866661A (fr) 1978-11-03
DE2819453C2 (fi) 1993-02-25
SE436569B (sv) 1985-01-07
JPH0260678B2 (fi) 1990-12-17
IE46873B1 (en) 1983-10-19
LU79598A1 (fr) 1979-02-02
IT1104190B (it) 1985-10-21
SE7804447L (sv) 1978-11-06
IT7849176A0 (it) 1978-05-03
DE2819453A1 (de) 1978-11-09
NL7804229A (nl) 1978-11-07
IE780849L (en) 1978-11-05
CH637962A5 (en) 1983-08-31
JPS53137993A (en) 1978-12-01

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Legal Events

Date Code Title Description
ST Notification of lapse