FR2384792A1 - PREDNISOLONE-9 FLUORO-DERIVATIVES FOR USE AS ACTIVE SUBSTANCES OF MEDICINAL PRODUCTS - Google Patents

PREDNISOLONE-9 FLUORO-DERIVATIVES FOR USE AS ACTIVE SUBSTANCES OF MEDICINAL PRODUCTS

Info

Publication number
FR2384792A1
FR2384792A1 FR7808099A FR7808099A FR2384792A1 FR 2384792 A1 FR2384792 A1 FR 2384792A1 FR 7808099 A FR7808099 A FR 7808099A FR 7808099 A FR7808099 A FR 7808099A FR 2384792 A1 FR2384792 A1 FR 2384792A1
Authority
FR
France
Prior art keywords
derivatives
prednisolone
fluoro
active substances
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7808099A
Other languages
French (fr)
Other versions
FR2384792B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2712862A external-priority patent/DE2712862C2/en
Priority claimed from DE19782809732 external-priority patent/DE2809732C2/en
Application filed by Schering AG filed Critical Schering AG
Publication of FR2384792A1 publication Critical patent/FR2384792A1/en
Application granted granted Critical
Publication of FR2384792B1 publication Critical patent/FR2384792B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Dérivés de la fluoro-9 prednisolone. Ils répondent à la formule :Derivatives of 9-fluoro prednisolone. They answer the formula:

FR7808099A 1977-03-21 1978-03-21 PREDNISOLONE-9 FLUORO-DERIVATIVES FOR USE AS ACTIVE SUBSTANCES OF MEDICINAL PRODUCTS Granted FR2384792A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2712862A DE2712862C2 (en) 1977-03-21 1977-03-21 Derivatives of 9-fluorprednisolone, process for their preparation and pharmaceuticals containing them
DE19782809732 DE2809732C2 (en) 1978-03-03 1978-03-03 Derivatives of 9-fluorprednisolone, process for their production, and pharmaceutical preparations containing these active ingredients

Publications (2)

Publication Number Publication Date
FR2384792A1 true FR2384792A1 (en) 1978-10-20
FR2384792B1 FR2384792B1 (en) 1980-04-04

Family

ID=25771793

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7808099A Granted FR2384792A1 (en) 1977-03-21 1978-03-21 PREDNISOLONE-9 FLUORO-DERIVATIVES FOR USE AS ACTIVE SUBSTANCES OF MEDICINAL PRODUCTS

Country Status (20)

Country Link
JP (1) JPS53130651A (en)
AT (1) AT365203B (en)
AU (1) AU525614B2 (en)
CA (1) CA1104124A (en)
CH (1) CH638226A5 (en)
CS (1) CS202591B2 (en)
DD (1) DD134955A5 (en)
DK (1) DK126378A (en)
ES (1) ES468107A1 (en)
FR (1) FR2384792A1 (en)
GB (1) GB1603281A (en)
GR (1) GR70385B (en)
IE (1) IE46584B1 (en)
IL (1) IL54308A (en)
IT (1) IT1095477B (en)
LU (1) LU79271A1 (en)
NO (1) NO151043C (en)
NZ (1) NZ186735A (en)
RO (1) RO81525B (en)
SE (1) SE431656B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012271A1 (en) * 1978-12-11 1980-06-25 Schering Aktiengesellschaft Prednisone derivatives, process for their production and pharmaceutical preparations containing these compounds
EP0393658A2 (en) * 1989-04-19 1990-10-24 Ss Pharmaceutical Co., Ltd. Novel steroid derivatives

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07213320A (en) * 1994-02-04 1995-08-15 Daiwa:Kk Bag for long sized article

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride
CH529739A (en) * 1972-02-28 1972-10-31 Sdc Steroidi Dev Co 11,16,17,21-tetrahydroxy-3,20-diketo-1,4-pregnadienes prepn - - from cpds without 16-hydroxy grp
US3832366A (en) * 1973-07-30 1974-08-27 Squibb & Sons Inc Process for preparing 21-chloro-17-acyloxy-20-ketosteroids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride
CH529739A (en) * 1972-02-28 1972-10-31 Sdc Steroidi Dev Co 11,16,17,21-tetrahydroxy-3,20-diketo-1,4-pregnadienes prepn - - from cpds without 16-hydroxy grp
US3832366A (en) * 1973-07-30 1974-08-27 Squibb & Sons Inc Process for preparing 21-chloro-17-acyloxy-20-ketosteroids

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012271A1 (en) * 1978-12-11 1980-06-25 Schering Aktiengesellschaft Prednisone derivatives, process for their production and pharmaceutical preparations containing these compounds
EP0393658A2 (en) * 1989-04-19 1990-10-24 Ss Pharmaceutical Co., Ltd. Novel steroid derivatives
EP0393658A3 (en) * 1989-04-19 1991-10-02 Ss Pharmaceutical Co., Ltd. Novel steroid derivatives

Also Published As

Publication number Publication date
ES468107A1 (en) 1979-07-01
SE431656B (en) 1984-02-20
CS202591B2 (en) 1981-01-30
FR2384792B1 (en) 1980-04-04
IT1095477B (en) 1985-08-10
DK126378A (en) 1978-09-22
CA1104124A (en) 1981-06-30
IE780545L (en) 1978-09-21
AT365203B (en) 1981-12-28
AU525614B2 (en) 1982-11-18
JPS6131116B2 (en) 1986-07-17
GB1603281A (en) 1981-11-25
CH638226A5 (en) 1983-09-15
IE46584B1 (en) 1983-07-27
JPS53130651A (en) 1978-11-14
IL54308A (en) 1984-03-30
DD134955A5 (en) 1979-04-04
RO81525A (en) 1983-04-29
GR70385B (en) 1982-10-05
IL54308A0 (en) 1978-06-15
RO81525B (en) 1983-04-30
NO151043C (en) 1985-01-30
LU79271A1 (en) 1978-06-29
ATA195978A (en) 1981-05-15
NO780984L (en) 1978-09-22
NZ186735A (en) 1980-10-24
SE7803168L (en) 1978-09-22
NO151043B (en) 1984-10-22
AU3434678A (en) 1979-09-27
IT7821364A0 (en) 1978-03-20

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Legal Events

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