FR2384501A1 - Agent immunostimulateur contenant une matiere peptidoglycanique, son procede de preparation et composition le contenant - Google Patents

Agent immunostimulateur contenant une matiere peptidoglycanique, son procede de preparation et composition le contenant

Info

Publication number
FR2384501A1
FR2384501A1 FR7808133A FR7808133A FR2384501A1 FR 2384501 A1 FR2384501 A1 FR 2384501A1 FR 7808133 A FR7808133 A FR 7808133A FR 7808133 A FR7808133 A FR 7808133A FR 2384501 A1 FR2384501 A1 FR 2384501A1
Authority
FR
France
Prior art keywords
peptidoglycanic
preparation process
immunostimulator
composition containing
peptidoglycans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7808133A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Glaxo Wellcome SA
Glaxo Laboratories Ltd
Original Assignee
Laboratoires Glaxo SA
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Glaxo SA, Glaxo Laboratories Ltd filed Critical Laboratoires Glaxo SA
Publication of FR2384501A1 publication Critical patent/FR2384501A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention a pour objet un procédé de préparation de fractions hydrosolubles à propriétés immunostimulatrices à partir de mycélium de Streptomyces griseus et contenant des peptidoglycanes et des compositions contenant de telles fractions. On traite une souche de Streptomyces griseus pour solubiliser les peptidoglycanes liés des parois des cellules et obtenir une fraction ayant l'activité immunostimulatrice désirée et on élimine les acides nucléiques. Production accrue d'anticorps et amélioration de l'immunité par l'entremise des cellules.
FR7808133A 1977-03-22 1978-03-21 Agent immunostimulateur contenant une matiere peptidoglycanique, son procede de preparation et composition le contenant Withdrawn FR2384501A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12090/77A GB1598457A (en) 1977-03-22 1977-03-22 Process for the preparation of a fraction containing peptidoglycan material from streptomyces griseus

Publications (1)

Publication Number Publication Date
FR2384501A1 true FR2384501A1 (fr) 1978-10-20

Family

ID=9998232

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7808133A Withdrawn FR2384501A1 (fr) 1977-03-22 1978-03-21 Agent immunostimulateur contenant une matiere peptidoglycanique, son procede de preparation et composition le contenant

Country Status (6)

Country Link
US (1) US4157278A (fr)
JP (1) JPS53118593A (fr)
DE (1) DE2812343A1 (fr)
FR (1) FR2384501A1 (fr)
GB (1) GB1598457A (fr)
NL (1) NL7803034A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995017902A1 (fr) * 1993-12-17 1995-07-06 Krestyanskoe Khozyaistvo 'agrofirma Dizha' Utilisation d'une souche du champignon fusarium comme producteur de substances et preparation a base celle-ci presentant, des proprietes, adaptogeniques et immunomodulatrices

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994381A (en) * 1986-04-07 1991-02-19 American Home Products Corporation N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylglycine S-oxide and the amide thereof
EP3589726A1 (fr) 2017-02-28 2020-01-08 Alimentary Health Limited Bifidobacterium longum apte à moduler de manière bénéfique une réponse immunitaire à l'encontre d'une infection virale respiratoire
AU2018227020B2 (en) 2017-02-28 2023-08-17 Precisionbiotics Group Limited Bifidobacterium longum able to beneficially modulate immune response to respiratory virus infection

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3421981A (en) * 1965-06-09 1969-01-14 Byron E Leach Production of therapeutic and prophylactic agent for upper respiratory infections
FR2322609A1 (fr) * 1975-09-03 1977-04-01 Hitachi Chemical Co Ltd Composition presentant une activite biologique et son procede de preparation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1046770A (en) * 1963-05-14 1966-10-26 James Harrison Stanton Therapeutic composition containing mycelial matter
US3616243A (en) * 1968-08-09 1971-10-26 Meiji Seika Kaisha Process for the production of an antibiotic substance 2'-amino-2'-deoxy-kanamycin in higher yield
US3855197A (en) * 1969-05-20 1974-12-17 Cassenne Lab Sa Glycoproteins extracted from microorganisms
US3716452A (en) * 1970-09-17 1973-02-13 Kirin Brewery Lysis of yeast cell walls
GB1426042A (en) * 1971-11-26 1976-02-25 Anvar water-soluble immunological adjuvants
FR2160326B1 (fr) * 1971-11-19 1975-02-07 Anvar
US4032663A (en) * 1971-12-14 1977-06-28 Kumiai Chemical Industry Co., Ltd. Process for using cell wall-lysing enzymes
FR2184531B1 (fr) * 1972-05-19 1975-10-17 Anvar
US3868303A (en) * 1972-11-06 1975-02-25 Nat Food Res Method of producing enzyme and its utilization thereof
US3917510A (en) * 1973-04-11 1975-11-04 Kirin Brewery Lysis of yeast cell walls
US3976544A (en) * 1973-06-19 1976-08-24 The Agence Nationale De Valorisation De Le Recherche Water-soluble immunological adjuvants, in particular for vaccines, obtained from mycobacteria and related microorganisms and process for their extraction
FR2269961B1 (fr) * 1974-05-06 1978-03-24 Anvar

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3421981A (en) * 1965-06-09 1969-01-14 Byron E Leach Production of therapeutic and prophylactic agent for upper respiratory infections
FR2322609A1 (fr) * 1975-09-03 1977-04-01 Hitachi Chemical Co Ltd Composition presentant une activite biologique et son procede de preparation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995017902A1 (fr) * 1993-12-17 1995-07-06 Krestyanskoe Khozyaistvo 'agrofirma Dizha' Utilisation d'une souche du champignon fusarium comme producteur de substances et preparation a base celle-ci presentant, des proprietes, adaptogeniques et immunomodulatrices
US5759543A (en) * 1993-12-17 1998-06-02 Krestyanskoe Khozyaistvo "Agrofirmadizha" Application of a cell culture of a fusarium fungus strain producer for medical uses

Also Published As

Publication number Publication date
GB1598457A (en) 1981-09-23
NL7803034A (nl) 1978-09-26
DE2812343A1 (de) 1978-10-12
JPS53118593A (en) 1978-10-17
US4157278A (en) 1979-06-05

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Legal Events

Date Code Title Description
ST Notification of lapse