GB1046770A - Therapeutic composition containing mycelial matter - Google Patents

Therapeutic composition containing mycelial matter

Info

Publication number
GB1046770A
GB1046770A GB1916863A GB1916863A GB1046770A GB 1046770 A GB1046770 A GB 1046770A GB 1916863 A GB1916863 A GB 1916863A GB 1916863 A GB1916863 A GB 1916863A GB 1046770 A GB1046770 A GB 1046770A
Authority
GB
United Kingdom
Prior art keywords
protoplasm
mycelium
mycelial
polynucleotide
instructional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1916863A
Inventor
Robert Dane Barnard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHARLES COLLIER STANTON
HENRY THOMPSON STANTON
Original Assignee
CHARLES COLLIER STANTON
HENRY THOMPSON STANTON
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHARLES COLLIER STANTON, HENRY THOMPSON STANTON filed Critical CHARLES COLLIER STANTON
Priority to GB1916863A priority Critical patent/GB1046770A/en
Publication of GB1046770A publication Critical patent/GB1046770A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

Abstract

An acid-insoluble instructional oligopoly-nucleotide is obtained from the mycelium of Streptomyces, Pencillium, Aspergillus, Zygomycetes, Saccharomycetes or Ustilago by (a) rendering the mycelium non-viable (b) disrupting the cell walls of the non-viable mycelium to obtain access to the polynucleotide-containing mycelial protoplasm, and (c) effecting a partial depolymerization of the polynucleotide components contained in the mycelial protoplasm to give oligopolynucleotides having molecular weights in the range 600-1, 000, 000; the pH of the aqueous medium in which any of the steps (a), (b) and (c) may be carried out being in the range 2.7 to 11.3 to avoid disorganization of the instructional nucleotide sequence of the polynucleotide components contained in the protoplasm. Thereapeutical compositions for oral or parenteral administration to humans and animal comprises an acid-insoluble oligopolynucleotide as above.
GB1916863A 1963-05-14 1963-05-14 Therapeutic composition containing mycelial matter Expired GB1046770A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1916863A GB1046770A (en) 1963-05-14 1963-05-14 Therapeutic composition containing mycelial matter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1916863A GB1046770A (en) 1963-05-14 1963-05-14 Therapeutic composition containing mycelial matter

Publications (1)

Publication Number Publication Date
GB1046770A true GB1046770A (en) 1966-10-26

Family

ID=10124885

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1916863A Expired GB1046770A (en) 1963-05-14 1963-05-14 Therapeutic composition containing mycelial matter

Country Status (1)

Country Link
GB (1) GB1046770A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617659A1 (en) * 1966-12-23 1971-04-01 Merck & Co Inc Polynucleotides which are effective as compounds inducing interferon production in living animal cells
US4154821A (en) * 1977-01-27 1979-05-15 Roussel Uclaf Novel glycoproteins
US4157278A (en) * 1977-03-22 1979-06-05 Glaxo Laboratories Limited Immunostimulatory agents
EP0107161A2 (en) * 1982-10-26 1984-05-02 CTA Finanz AG Device and process for optimising the tissue mass of organs within the genetic fluctuation range in humans and animals

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617659A1 (en) * 1966-12-23 1971-04-01 Merck & Co Inc Polynucleotides which are effective as compounds inducing interferon production in living animal cells
US4154821A (en) * 1977-01-27 1979-05-15 Roussel Uclaf Novel glycoproteins
US4157278A (en) * 1977-03-22 1979-06-05 Glaxo Laboratories Limited Immunostimulatory agents
EP0107161A2 (en) * 1982-10-26 1984-05-02 CTA Finanz AG Device and process for optimising the tissue mass of organs within the genetic fluctuation range in humans and animals
EP0107161A3 (en) * 1982-10-26 1984-06-06 Cta Finanz Ag Device and process for optimising the tissue mass of organs within the genetic fluctuation range in humans and animals

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