FR2399836A1 - Procede de preparation de produits biocompatibles et articles ainsi obtenus - Google Patents
Procede de preparation de produits biocompatibles et articles ainsi obtenusInfo
- Publication number
- FR2399836A1 FR2399836A1 FR7822106A FR7822106A FR2399836A1 FR 2399836 A1 FR2399836 A1 FR 2399836A1 FR 7822106 A FR7822106 A FR 7822106A FR 7822106 A FR7822106 A FR 7822106A FR 2399836 A1 FR2399836 A1 FR 2399836A1
- Authority
- FR
- France
- Prior art keywords
- articles
- preparing biocompatible
- biocompatible products
- products
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000003124 biologic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G85/00—General processes for preparing compounds provided for in this subclass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/062—Mixtures of macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
- C08B15/05—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur
- C08B15/06—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur containing nitrogen, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/30—Low-molecular-weight compounds
- C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
- C08G18/3819—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen
- C08G18/3842—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing heterocyclic rings having at least one nitrogen atom in the ring
- C08G18/3844—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing heterocyclic rings having at least one nitrogen atom in the ring containing one nitrogen atom in the ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials For Medical Uses (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
Procédé de préparation de produits biocompatibles et articles ainsi obtenus. Dans ce procédé on traite un produit polymère avec un agent d'hydrolyse à sa surface et on y lie de manière covalente un agent biologique, tel qu'un agent non-agglutinant les plaquettes. Utilisation de ce procédé pour fabriquer des articles prosthétiques biocompatibles.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT26191/77A IT1081627B (it) | 1977-07-27 | 1977-07-27 | Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2399836A1 true FR2399836A1 (fr) | 1979-03-09 |
FR2399836B1 FR2399836B1 (fr) | 1983-02-04 |
Family
ID=11218887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7822106A Granted FR2399836A1 (fr) | 1977-07-27 | 1978-07-26 | Procede de preparation de produits biocompatibles et articles ainsi obtenus |
Country Status (11)
Country | Link |
---|---|
US (1) | US4243776A (fr) |
JP (1) | JPS5424986A (fr) |
BE (1) | BE869323A (fr) |
CA (1) | CA1103158A (fr) |
CH (1) | CH643276A5 (fr) |
DE (1) | DE2833072A1 (fr) |
FR (1) | FR2399836A1 (fr) |
GB (1) | GB2001663B (fr) |
IT (1) | IT1081627B (fr) |
LU (1) | LU80031A1 (fr) |
NL (1) | NL7807986A (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2410013A1 (fr) * | 1977-11-23 | 1979-06-22 | Unitika Ltd | Procede pour preparer un article polymere antithrombogene |
EP0142512A1 (fr) * | 1983-04-20 | 1985-05-29 | Limit Instant Limited | Traitement de membranes |
EP0523555A1 (fr) * | 1991-07-11 | 1993-01-20 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Composition pharmaceutique utile pour inhiber la dégradation biologique du matérial polymérique d'implantation |
EP0568451A1 (fr) * | 1992-04-28 | 1993-11-03 | Terumo Kabushiki Kaisha | Composition de polymère thermoplastique et dispositifs médicaux fabriqués à partir de ceux-ci |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4548994A (en) * | 1981-12-03 | 1985-10-22 | The Upjohn Company | Isolation of bacterial luciferase |
US4820302A (en) * | 1982-04-22 | 1989-04-11 | Sterling Drug Inc. | Bio compatible and blood compatible materials and methods |
US4521564A (en) * | 1984-02-10 | 1985-06-04 | Warner-Lambert Company | Covalent bonded antithrombogenic polyurethane material |
US5338770A (en) * | 1988-06-08 | 1994-08-16 | Cardiopulmonics, Inc. | Gas permeable thrombo-resistant coatings and methods of manufacture |
US5262451A (en) * | 1988-06-08 | 1993-11-16 | Cardiopulmonics, Inc. | Multifunctional thrombo-resistant coatings and methods of manufacture |
US5342693A (en) * | 1988-06-08 | 1994-08-30 | Cardiopulmonics, Inc. | Multifunctional thrombo-resistant coating and methods of manufacture |
US5182317A (en) * | 1988-06-08 | 1993-01-26 | Cardiopulmonics, Inc. | Multifunctional thrombo-resistant coatings and methods of manufacture |
US5891196A (en) * | 1997-04-16 | 1999-04-06 | Baxter International Inc. | Method for actively binding heparin to crosslinked biological tissues |
CA2436792A1 (fr) | 2000-12-01 | 2002-06-06 | 3M Innovative Properties Company | Compositions de fluoroelastomeres durcissables contenant des hydrosiloxanes ou des hydrosilazanes |
JP4898465B2 (ja) * | 2007-01-18 | 2012-03-14 | スタンレー電気株式会社 | 車両用前照灯 |
US8505220B2 (en) * | 2010-03-04 | 2013-08-13 | Nike, Inc. | Flex groove sole assembly with biasing structure |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3441142A (en) * | 1966-07-21 | 1969-04-29 | Dow Chemical Co | Nonthrombogenic plastic membranes |
FR2014632A1 (fr) * | 1968-07-17 | 1970-04-17 | Massachusetts Inst Technology | |
US3617344A (en) * | 1966-08-05 | 1971-11-02 | Us Health Education & Welfare | Nonthrombogenic plastic surfaces and preparation thereof |
FR2187849A1 (fr) * | 1972-06-06 | 1974-01-18 | Atomic Energy Commission | |
DE2421655A1 (de) * | 1973-05-07 | 1974-11-28 | Air Prod & Chem | Thermoplastische werkstoffe ohne thrombose erzeugende wirkung |
FR2250795A1 (en) * | 1973-11-12 | 1975-06-06 | Univ Washington | Heparinised polymer article for counter-acting blood-clot formation - prepd by reacting bromo-cyanide with hydrophilic polymer before reaction with heparin |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3371069A (en) * | 1963-03-20 | 1968-02-27 | Ajinomoto Kk | Filaments and surgical sutures of polyl-glutamic acid partly esterified with lower alkanols and process therefor |
US3994866A (en) * | 1968-10-14 | 1976-11-30 | The Dow Chemical Company | Aminoalkylating polymer containing plurality of --CO--NH-- amide groups as integral parts of main polymer chain |
US3711583A (en) * | 1969-12-31 | 1973-01-16 | L Sklar | Method of producing polyamide membranes and rigid foamed products |
FR2182667B1 (fr) * | 1972-05-03 | 1978-03-03 | Rhone Poulenc Ind | |
IL42516A (en) * | 1973-06-15 | 1976-11-30 | Mordechai Sokolovsky | Polyamides are converted by aldehyde and isonitrile groups and a process for their preparation |
US4069105A (en) * | 1977-03-03 | 1978-01-17 | Syva Company | Lidocaine antigens and antibodies |
-
1977
- 1977-07-27 IT IT26191/77A patent/IT1081627B/it active
-
1978
- 1978-06-21 US US05/917,568 patent/US4243776A/en not_active Expired - Lifetime
- 1978-06-22 CA CA305,975A patent/CA1103158A/fr not_active Expired
- 1978-07-04 GB GB787828822A patent/GB2001663B/en not_active Expired
- 1978-07-21 CH CH793978A patent/CH643276A5/it not_active IP Right Cessation
- 1978-07-24 JP JP8953078A patent/JPS5424986A/ja active Pending
- 1978-07-24 LU LU80031A patent/LU80031A1/xx unknown
- 1978-07-26 FR FR7822106A patent/FR2399836A1/fr active Granted
- 1978-07-27 BE BE189542A patent/BE869323A/fr not_active IP Right Cessation
- 1978-07-27 DE DE19782833072 patent/DE2833072A1/de not_active Ceased
- 1978-07-27 NL NL7807986A patent/NL7807986A/xx not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3441142A (en) * | 1966-07-21 | 1969-04-29 | Dow Chemical Co | Nonthrombogenic plastic membranes |
US3617344A (en) * | 1966-08-05 | 1971-11-02 | Us Health Education & Welfare | Nonthrombogenic plastic surfaces and preparation thereof |
FR2014632A1 (fr) * | 1968-07-17 | 1970-04-17 | Massachusetts Inst Technology | |
FR2187849A1 (fr) * | 1972-06-06 | 1974-01-18 | Atomic Energy Commission | |
DE2421655A1 (de) * | 1973-05-07 | 1974-11-28 | Air Prod & Chem | Thermoplastische werkstoffe ohne thrombose erzeugende wirkung |
FR2250795A1 (en) * | 1973-11-12 | 1975-06-06 | Univ Washington | Heparinised polymer article for counter-acting blood-clot formation - prepd by reacting bromo-cyanide with hydrophilic polymer before reaction with heparin |
Non-Patent Citations (1)
Title |
---|
CA1974 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2410013A1 (fr) * | 1977-11-23 | 1979-06-22 | Unitika Ltd | Procede pour preparer un article polymere antithrombogene |
EP0142512A1 (fr) * | 1983-04-20 | 1985-05-29 | Limit Instant Limited | Traitement de membranes |
EP0142512A4 (fr) * | 1983-04-20 | 1988-01-11 | Limit Instant Ltd | Traitement de membranes. |
EP0523555A1 (fr) * | 1991-07-11 | 1993-01-20 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Composition pharmaceutique utile pour inhiber la dégradation biologique du matérial polymérique d'implantation |
US5302393A (en) * | 1991-07-11 | 1994-04-12 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor |
EP0568451A1 (fr) * | 1992-04-28 | 1993-11-03 | Terumo Kabushiki Kaisha | Composition de polymère thermoplastique et dispositifs médicaux fabriqués à partir de ceux-ci |
US5417981A (en) * | 1992-04-28 | 1995-05-23 | Terumo Kabushiki Kaisha | Thermoplastic polymer composition and medical devices made of the same |
Also Published As
Publication number | Publication date |
---|---|
CH643276A5 (it) | 1984-05-30 |
DE2833072A1 (de) | 1979-02-01 |
US4243776A (en) | 1981-01-06 |
BE869323A (fr) | 1979-01-29 |
IT1081627B (it) | 1985-05-21 |
NL7807986A (nl) | 1979-01-30 |
JPS5424986A (en) | 1979-02-24 |
CA1103158A (fr) | 1981-06-16 |
LU80031A1 (fr) | 1978-12-12 |
FR2399836B1 (fr) | 1983-02-04 |
GB2001663A (en) | 1979-02-07 |
GB2001663B (en) | 1982-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
ST | Notification of lapse |