IT1081627B - Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti - Google Patents

Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti

Info

Publication number
IT1081627B
IT1081627B IT26191/77A IT2619177A IT1081627B IT 1081627 B IT1081627 B IT 1081627B IT 26191/77 A IT26191/77 A IT 26191/77A IT 2619177 A IT2619177 A IT 2619177A IT 1081627 B IT1081627 B IT 1081627B
Authority
IT
Italy
Prior art keywords
manufactures
procedure
preparation
biocompatible materials
biocompatible
Prior art date
Application number
IT26191/77A
Other languages
English (en)
Inventor
Walter Marconi
Francesco Pittalis
Francesco Bartoli
Franco Morisi
Original Assignee
Snam Progetti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snam Progetti filed Critical Snam Progetti
Priority to IT26191/77A priority Critical patent/IT1081627B/it
Priority to US05/917,568 priority patent/US4243776A/en
Priority to CA305,975A priority patent/CA1103158A/en
Priority to GB787828822A priority patent/GB2001663B/en
Priority to CH793978A priority patent/CH643276A5/it
Priority to LU80031A priority patent/LU80031A1/xx
Priority to JP8953078A priority patent/JPS5424986A/ja
Priority to FR7822106A priority patent/FR2399836A1/fr
Priority to NL7807986A priority patent/NL7807986A/xx
Priority to DE19782833072 priority patent/DE2833072A1/de
Priority to BE189542A priority patent/BE869323A/xx
Application granted granted Critical
Publication of IT1081627B publication Critical patent/IT1081627B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G85/00—General processes for preparing compounds provided for in this subclass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595—Polyamides, e.g. nylon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/062—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/05—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur
    • C08B15/06—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur containing nitrogen, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
    • C08G18/3819—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen
    • C08G18/3842—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing heterocyclic rings having at least one nitrogen atom in the ring
    • C08G18/3844—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing heterocyclic rings having at least one nitrogen atom in the ring containing one nitrogen atom in the ring
IT26191/77A 1977-07-27 1977-07-27 Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti IT1081627B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT26191/77A IT1081627B (it) 1977-07-27 1977-07-27 Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti
US05/917,568 US4243776A (en) 1977-07-27 1978-06-21 Preparation of non-thrombogenic polymeric material article with platelet anti-aggregative agent
CA305,975A CA1103158A (en) 1977-07-27 1978-06-22 Method for preparing biocompatible materials and articles produced thereby
GB787828822A GB2001663B (en) 1977-07-27 1978-07-04 Biocompatible materials and articles
CH793978A CH643276A5 (it) 1977-07-27 1978-07-21 Procedimento per ottenere omo- e copolimeri biocompatibili e utilizzazione degli omo- e copolimeri ottenuti.
LU80031A LU80031A1 (it) 1977-07-27 1978-07-24
JP8953078A JPS5424986A (en) 1977-07-27 1978-07-24 Method of making microbiological compatibility material
FR7822106A FR2399836A1 (fr) 1977-07-27 1978-07-26 Procede de preparation de produits biocompatibles et articles ainsi obtenus
NL7807986A NL7807986A (nl) 1977-07-27 1978-07-27 Werkwijze voor de bereiding van biologisch-verdraagbare materialen alsmede daaruit vervaardigde voorwerpen.
DE19782833072 DE2833072A1 (de) 1977-07-27 1978-07-27 Verfahren zur herstellung von biologisch vertraeglichen materialien und die nach diesem verfahren erhaltenen gegenstaende
BE189542A BE869323A (fr) 1977-07-27 1978-07-27 Procede de preparation de produits biocompatibles et articles ainsi obtenus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26191/77A IT1081627B (it) 1977-07-27 1977-07-27 Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti

Publications (1)

Publication Number Publication Date
IT1081627B true IT1081627B (it) 1985-05-21

Family

ID=11218887

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26191/77A IT1081627B (it) 1977-07-27 1977-07-27 Procedimento per la preparazione di materiali biocompatibili e manufatti cosi' ottenuti

Country Status (11)

Country Link
US (1) US4243776A (it)
JP (1) JPS5424986A (it)
BE (1) BE869323A (it)
CA (1) CA1103158A (it)
CH (1) CH643276A5 (it)
DE (1) DE2833072A1 (it)
FR (1) FR2399836A1 (it)
GB (1) GB2001663B (it)
IT (1) IT1081627B (it)
LU (1) LU80031A1 (it)
NL (1) NL7807986A (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2410013A1 (fr) * 1977-11-23 1979-06-22 Unitika Ltd Procede pour preparer un article polymere antithrombogene
US4548994A (en) * 1981-12-03 1985-10-22 The Upjohn Company Isolation of bacterial luciferase
US4820302A (en) * 1982-04-22 1989-04-11 Sterling Drug Inc. Bio compatible and blood compatible materials and methods
GB8310666D0 (en) * 1983-04-20 1983-05-25 Limit Instant Ltd Treatment of membranes
US4521564A (en) * 1984-02-10 1985-06-04 Warner-Lambert Company Covalent bonded antithrombogenic polyurethane material
US5338770A (en) * 1988-06-08 1994-08-16 Cardiopulmonics, Inc. Gas permeable thrombo-resistant coatings and methods of manufacture
US5262451A (en) * 1988-06-08 1993-11-16 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US5182317A (en) * 1988-06-08 1993-01-26 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US5342693A (en) * 1988-06-08 1994-08-30 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coating and methods of manufacture
US5302393A (en) * 1991-07-11 1994-04-12 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor
EP0568451B1 (en) * 1992-04-28 1999-08-04 Terumo Kabushiki Kaisha Thermoplastic polymer composition and medical devices made of the same
US5891196A (en) * 1997-04-16 1999-04-06 Baxter International Inc. Method for actively binding heparin to crosslinked biological tissues
ATE304577T1 (de) 2000-12-01 2005-09-15 3M Innovative Properties Co Härtbare fluorelastomer-zusammensetzungen enthaltend hydrosiloxane oder hydrosilazane
JP4898465B2 (ja) * 2007-01-18 2012-03-14 スタンレー電気株式会社 車両用前照灯
US8505220B2 (en) * 2010-03-04 2013-08-13 Nike, Inc. Flex groove sole assembly with biasing structure

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371069A (en) * 1963-03-20 1968-02-27 Ajinomoto Kk Filaments and surgical sutures of polyl-glutamic acid partly esterified with lower alkanols and process therefor
US3441142A (en) * 1966-07-21 1969-04-29 Dow Chemical Co Nonthrombogenic plastic membranes
US3617344A (en) * 1966-08-05 1971-11-02 Us Health Education & Welfare Nonthrombogenic plastic surfaces and preparation thereof
DE1936387A1 (de) * 1968-07-17 1970-01-22 Massachusetts Inst Technology Nichtthrombogene Materialien und Verfahren zu ihrer Herstellung
US3994866A (en) * 1968-10-14 1976-11-30 The Dow Chemical Company Aminoalkylating polymer containing plurality of --CO--NH-- amide groups as integral parts of main polymer chain
US3711583A (en) * 1969-12-31 1973-01-16 L Sklar Method of producing polyamide membranes and rigid foamed products
FR2182667B1 (it) * 1972-05-03 1978-03-03 Rhone Poulenc Ind
US3826678A (en) * 1972-06-06 1974-07-30 Atomic Energy Commission Method for preparation of biocompatible and biofunctional materials and product thereof
US3865615A (en) * 1973-05-07 1975-02-11 Air Prod & Chem Non-thrombogenic plastics
IL42516A (en) * 1973-06-15 1976-11-30 Mordechai Sokolovsky Polyamides are converted by aldehyde and isonitrile groups and a process for their preparation
FR2250795A1 (en) * 1973-11-12 1975-06-06 Univ Washington Heparinised polymer article for counter-acting blood-clot formation - prepd by reacting bromo-cyanide with hydrophilic polymer before reaction with heparin
US4069105A (en) * 1977-03-03 1978-01-17 Syva Company Lidocaine antigens and antibodies

Also Published As

Publication number Publication date
US4243776A (en) 1981-01-06
LU80031A1 (it) 1978-12-12
GB2001663A (en) 1979-02-07
JPS5424986A (en) 1979-02-24
CA1103158A (en) 1981-06-16
GB2001663B (en) 1982-04-28
DE2833072A1 (de) 1979-02-01
FR2399836A1 (fr) 1979-03-09
NL7807986A (nl) 1979-01-30
FR2399836B1 (it) 1983-02-04
BE869323A (fr) 1979-01-29
CH643276A5 (it) 1984-05-30

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