FR2187849A1 - - Google Patents

Info

Publication number
FR2187849A1
FR2187849A1 FR7320646A FR7320646A FR2187849A1 FR 2187849 A1 FR2187849 A1 FR 2187849A1 FR 7320646 A FR7320646 A FR 7320646A FR 7320646 A FR7320646 A FR 7320646A FR 2187849 A1 FR2187849 A1 FR 2187849A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7320646A
Other versions
FR2187849B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Atomic Energy Commission (AEC)
Original Assignee
US Atomic Energy Commission (AEC)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Atomic Energy Commission (AEC) filed Critical US Atomic Energy Commission (AEC)
Publication of FR2187849A1 publication Critical patent/FR2187849A1/fr
Application granted granted Critical
Publication of FR2187849B1 publication Critical patent/FR2187849B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0011Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0047Enzymes, e.g. urokinase, streptokinase
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12Chemical modification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087Acrylic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/093Polyurethanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2375/00Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
    • C08J2375/04Polyurethanes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92Method or apparatus for preparing or treating prosthetic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31536Including interfacial reaction product of adjacent layers
FR7320646A 1972-06-06 1973-06-06 Expired FR2187849B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00260237A US3826678A (en) 1972-06-06 1972-06-06 Method for preparation of biocompatible and biofunctional materials and product thereof

Publications (2)

Publication Number Publication Date
FR2187849A1 true FR2187849A1 (fr) 1974-01-18
FR2187849B1 FR2187849B1 (fr) 1977-12-30

Family

ID=22988350

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7320646A Expired FR2187849B1 (fr) 1972-06-06 1973-06-06

Country Status (9)

Country Link
US (1) US3826678A (fr)
JP (1) JPS5736921B2 (fr)
BE (1) BE800536A (fr)
CH (1) CH593064A5 (fr)
DE (1) DE2326863A1 (fr)
FR (1) FR2187849B1 (fr)
GB (1) GB1391028A (fr)
NO (1) NO140429C (fr)
SE (1) SE400565B (fr)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399836A1 (fr) * 1977-07-27 1979-03-09 Snam Progetti Procede de preparation de produits biocompatibles et articles ainsi obtenus
FR2410013A1 (fr) * 1977-11-23 1979-06-22 Unitika Ltd Procede pour preparer un article polymere antithrombogene
FR2440733A1 (fr) * 1978-11-08 1980-06-06 Fydelor Peter Dispositif chirurgical biologiquement compatible, comprenant une matiere plastique
EP0029411A1 (fr) * 1979-11-15 1981-05-27 Battelle Memorial Institute Composition adhésive pour le dépôt d'un revêtement adhésif fixateur de molécules biofonctionnelles, revêtement obtenu et procédé pour sa préparation, substrat recouvert du revêtement et son utilisation comme biocatalyseur
EP0091128A2 (fr) * 1982-04-06 1983-10-12 THE STATE of ISRAEL Atomic Energy Commission Soreq Nuclear Research Center Matériau synthétique pour le recouvrement des plaies
FR2534486A1 (fr) * 1982-10-15 1984-04-20 Commissariat Energie Atomique Support particulaire greffe en surface, son procede de preparation et adsorbants pour chromatographie d'affinite incorporant ce support, ainsi que leur utilisation, notamment en biologie
EP0109943A2 (fr) * 1982-10-18 1984-05-30 Pharmacia Ab Procédé pour préparer des couches polymères
EP0110409A2 (fr) * 1982-12-02 1984-06-13 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant et procédé pour le préparer
FR2553518A1 (fr) * 1983-10-13 1985-04-19 Choay Sa Nouveaux conjugues elabores par fixation d'un ligand sur un support insoluble, leur preparation et leurs applications biologiques
EP0152699A2 (fr) * 1984-02-10 1985-08-28 Deseret Medical, Inc. Polymère de polyuréthane antithrombogène et procédé d'attribution d'activité antithrombogène à un substrat de polyuréthane
EP0200295A2 (fr) * 1985-04-01 1986-11-05 Deseret Medical, Inc. Surface antithrombogène en polyuréthane
WO1987000060A1 (fr) * 1985-07-08 1987-01-15 Battelle Memorial Institute Substrat dont la surface presente une activite antithrombogenique
EP0290642A1 (fr) * 1987-05-12 1988-11-17 Mittermayer, Christian, Dr. med. Procédé pour ensemencer des surfaces polymériques avec des cellules endothéliales humaines
EP0294905A1 (fr) * 1987-06-09 1988-12-14 Cordis Europa N.V. Fixation covalente d'anticoagulants et produits semblables aux matériaux biocompatibles
EP0428569A1 (fr) * 1988-08-03 1991-05-29 New England Deaconess Hospital Substance biocompatible a thromboresistance
NL9000362A (nl) * 1990-02-15 1991-09-02 Cordis Corp Werkwijze voor het aktiveren van een oppervlak van een substraat voor het koppelbaar maken van het oppervlak aan een door covalente binding op het oppervlak te immobiliseren materiaal, alsmede substraat, voorzien van een geaktiveerd oppervlak.
WO1991016932A1 (fr) * 1990-04-27 1991-11-14 Biocompatibles Limited Polymeres antithrombogenes
EP0608095A1 (fr) * 1993-01-19 1994-07-27 Medtronic, Inc. Fixation de biomolécules
FR2785812A1 (fr) * 1998-11-16 2000-05-19 Commissariat Energie Atomique Protheses bioactives, notamment a proprietes immunosuppressives, antistenose et antithrombose, et leur fabrication

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375414A (en) * 1971-05-20 1983-03-01 Meir Strahilevitz Immunological methods for removing species from the blood circulatory system and devices therefor
US3908657A (en) * 1973-01-15 1975-09-30 Univ Johns Hopkins System for continuous withdrawal of blood
US3865615A (en) * 1973-05-07 1975-02-11 Air Prod & Chem Non-thrombogenic plastics
GB1463301A (en) * 1973-07-18 1977-02-02 Highgate D J Polymer properties
US4178361A (en) * 1973-09-10 1979-12-11 Union Corporation Sustained release pharmaceutical composition
US4196065A (en) * 1973-11-09 1980-04-01 Commissariat A L'energie Atomique Hydrophobic substrate with grafted hydrophilic inclusions
JPS604212B2 (ja) * 1976-05-24 1985-02-02 ユニチカ株式会社 高分子物質に線溶活性を付与する方法
DE2751528A1 (de) * 1977-11-18 1979-05-23 Hoechst Ag Kunststoff-material mit verbesserter blutvertraeglichkeit
GB2041377B (en) * 1979-01-22 1983-09-28 Woodroof Lab Inc Bio compatible and blood compatible materials and methods
US4291133A (en) * 1979-04-05 1981-09-22 Vaclav Horak Nonthrombogenic polymer surface
IT1122388B (it) * 1979-08-01 1986-04-23 Anic Spa Procedimento per la preparazione di materiali biocompatibili tramite l'immobilizzazione superficiale di apirasi
US4305926A (en) * 1979-09-13 1981-12-15 Johannes Everse Immobilization of Streptokinase
JPS56145857A (en) * 1980-04-15 1981-11-12 Unitika Ltd Material for purifying body fluid and its manufacture
US4530974A (en) * 1981-03-19 1985-07-23 Board Of Regents, The University Of Texas System Nonthrombogenic articles having enhanced albumin affinity
US4451568A (en) * 1981-07-13 1984-05-29 Battelle Memorial Institute Composition for binding bioactive substances
US4505266A (en) * 1981-10-26 1985-03-19 Massachusetts Institute Of Technology Method of using a fibrous lattice
US4458678A (en) * 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4418691A (en) * 1981-10-26 1983-12-06 Massachusetts Institute Of Technology Method of promoting the regeneration of tissue at a wound
SE8200751L (sv) * 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
US4737544A (en) * 1982-08-12 1988-04-12 Biospecific Technologies, Inc. Biospecific polymers
US4687808A (en) * 1982-08-12 1987-08-18 Biospecific Technologies, Inc. Activation of biocompatible polymers with biologicals whose binding complements are pathological effectors
EP0103184B1 (fr) * 1982-08-12 1990-01-17 Kanegafuchi Chemical Industry Co., Ltd. Activation de terpolymères biocompatibles par des agents biologiques dont les compléments à fixer sont des effecteurs pathologiques
BR8304308A (pt) * 1982-08-12 1984-03-20 Diamond Shamrock Corp Membrana bioespecifica
JPS5956446A (ja) * 1982-09-24 1984-03-31 Nippon Oil Co Ltd ポリビニルアルコ−ル凍結ゲルの柔軟性低下法
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US5258041A (en) * 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4613517A (en) * 1983-04-27 1986-09-23 Becton, Dickinson And Company Heparinization of plasma treated surfaces
CA1236738A (fr) * 1983-06-01 1988-05-17 Mark R. Honard Dispositif therapeutique
US4685900A (en) * 1983-06-01 1987-08-11 Biospecific Technologies, Inc. Therapeutic device
US4499901A (en) * 1983-06-30 1985-02-19 Critikon, Inc. Retreated sensing electrode
JPS6083612U (ja) * 1983-11-16 1985-06-10 株式会社白元 保冷袋の保持具
JPS60177826U (ja) * 1984-01-06 1985-11-26 坂田 信一 帯状のカイロ保持器具
JPS6139529U (ja) * 1984-08-20 1986-03-12 株式会社 竹虎 サポ−タ−
ATE59195T1 (de) * 1984-11-23 1991-01-15 Ciba Geigy Ag Vormaterial aus mit kunststoff beschichteten fasern und verfahren zur herstellung eines solchen vormaterials.
DE3513938A1 (de) * 1985-04-18 1986-10-23 Merck Patent Gmbh, 6100 Darmstadt Cytostatikahaltiges pharmakadepot
WO1987005038A1 (fr) * 1986-02-17 1987-08-27 Commonwealth Scientific And Industrial Research Or Materiaux implantables
US5263992A (en) * 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4906374A (en) * 1986-12-23 1990-03-06 Pall Corporation Filtration media with low protein adsorbability
US4886836A (en) * 1987-06-03 1989-12-12 Pall Corporation Activated medium with low non-specific protein adsorption
EP0299698B1 (fr) * 1987-07-14 1992-09-09 Sankyo Company Limited Composition pour former des articles médicaux antithrombotiques
US5733254A (en) * 1987-10-15 1998-03-31 Cypress Bioscience, Inc. Method for treating patients suffering from immune thrombocytopenic purpura
US5182317A (en) * 1988-06-08 1993-01-26 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US5262451A (en) * 1988-06-08 1993-11-16 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US5338770A (en) * 1988-06-08 1994-08-16 Cardiopulmonics, Inc. Gas permeable thrombo-resistant coatings and methods of manufacture
US5342693A (en) * 1988-06-08 1994-08-30 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coating and methods of manufacture
DE3856430T2 (de) * 1988-07-22 2001-05-03 Surmodics Inc Herstellung von polymeren oberflächen
US5843156A (en) 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
US4959150A (en) * 1988-09-26 1990-09-25 Pall Corporation Fluid treatment system having low affinity for proteinaceous materials
US5073171A (en) * 1989-01-12 1991-12-17 Eaton John W Biocompatible materials comprising albumin-binding dyes
EP0491860B1 (fr) * 1989-09-15 1997-01-15 Chiron Vision Corporation Material synthetique pour supporter l'addition, la croissance et la fixation des cellules epitheliales, dispositif prothetique pour l'implantation subepitheliale et lentille traitee
US8067149B2 (en) * 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
CN1039590C (zh) * 1991-02-08 1998-08-26 中国科学技术大学 一种医用防粘连硅橡胶膜的制备方法
EP0527992B1 (fr) * 1991-03-06 1998-02-18 Sartorius Ag Procede de modification de la surface des membranes microporeuses, objets moules ainsi obtenus et leur utilisation pour la separation de substances par adsorption
US5356433A (en) * 1991-08-13 1994-10-18 Cordis Corporation Biocompatible metal surfaces
US5376692A (en) * 1992-05-15 1994-12-27 Purdue Research Foundation Method of binding using irradiation and product with albumin bound to biomaterials
US5344455A (en) * 1992-10-30 1994-09-06 Medtronic, Inc. Graft polymer articles having bioactive surfaces
US5278200A (en) * 1992-10-30 1994-01-11 Medtronic, Inc. Thromboresistant material and articles
US5336518A (en) * 1992-12-11 1994-08-09 Cordis Corporation Treatment of metallic surfaces using radiofrequency plasma deposition and chemical attachment of bioactive agents
US5308641A (en) * 1993-01-19 1994-05-03 Medtronic, Inc. Biocompatibility of solid surfaces
US5229172A (en) * 1993-01-19 1993-07-20 Medtronic, Inc. Modification of polymeric surface by graft polymerization
IT1268718B1 (it) * 1994-07-26 1997-03-06 Fidia Advanced Biopolymers Srl Sintesi di gel chimici da polisaccaridi polielettroliti tramite gamma irradiazione
US5532311A (en) * 1995-02-01 1996-07-02 Minnesota Mining And Manufacturing Company Process for modifying surfaces
US5750585A (en) * 1995-04-04 1998-05-12 Purdue Research Foundation Super absorbent hydrogel foams
US5583213A (en) * 1995-05-12 1996-12-10 Minnesota Mining And Manufacturing Company Process to activate sulfated polysaccharides
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US5672638A (en) * 1995-08-22 1997-09-30 Medtronic, Inc. Biocompatability for solid surfaces
US5767108A (en) * 1995-08-22 1998-06-16 Medtronic, Inc. Method for making improved heparinized biomaterials
US5925552A (en) * 1996-04-25 1999-07-20 Medtronic, Inc. Method for attachment of biomolecules to medical devices surfaces
US5821343A (en) * 1996-04-25 1998-10-13 Medtronic Inc Oxidative method for attachment of biomolecules to surfaces of medical devices
US5728420A (en) * 1996-08-09 1998-03-17 Medtronic, Inc. Oxidative method for attachment of glycoproteins to surfaces of medical devices
US6033719A (en) * 1996-04-25 2000-03-07 Medtronic, Inc. Method for covalent attachment of biomolecules to surfaces of medical devices
US5891506A (en) * 1996-08-09 1999-04-06 Medtronic, Inc. Oxidative method for attachment of glycoproteins or glycopeptides to surfaces of medical devices
US5945319A (en) * 1996-04-25 1999-08-31 Medtronic, Inc. Periodate oxidative method for attachment of biomolecules to medical device surfaces
US5928916A (en) * 1996-04-25 1999-07-27 Medtronic, Inc. Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces
US5879697A (en) * 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US6271278B1 (en) 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
US6146771A (en) * 1997-07-01 2000-11-14 Terumo Cardiovascular Systems Corporation Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine
US6197289B1 (en) 1997-07-01 2001-03-06 Terumo Cardiovascular Systems Corporation Removal of biologically active agents
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6664061B2 (en) 1999-06-25 2003-12-16 Amersham Biosciences Ab Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix
US6372813B1 (en) 1999-06-25 2002-04-16 Motorola Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays
AU2002258790A1 (en) * 2001-04-10 2002-10-28 The Trustees Of Columbia University In The City Of New York Novel microarrays and methods of use thereof
US7407668B2 (en) * 2002-01-24 2008-08-05 Boston Scimed, Inc. Medical articles having enzymatic surfaces for localized therapy
US20040033546A1 (en) 2002-04-10 2004-02-19 The Trustees Of Columbia University In The City Of New York Novel microarrays and methods of use thereof
ATE480573T1 (de) * 2002-07-29 2010-09-15 Life Technologies Corp Pfropfcopolymere, deren herstellung und verwendung bei der kapillarelektrophorese
US20090088846A1 (en) * 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US20060115455A1 (en) * 2004-10-22 2006-06-01 Reed Kenneth C Therapeutic RNAi agents for treating psoriasis
US20070004040A1 (en) * 2005-01-06 2007-01-04 Brashears Sarah J RNAi agents for maintenance of stem cells
US20090004253A1 (en) * 2007-06-29 2009-01-01 Brown Laura J Composite device for the repair or regeneration of tissue
EP2182798B1 (fr) * 2007-07-16 2020-11-18 Allvivo Vascular, Inc. Constructions antimicrobiennes
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
KR20110040969A (ko) * 2008-08-05 2011-04-20 바이오미메디카, 인코포레이티드 폴리우레탄-그라프트된 하이드로겔
EP2609154B1 (fr) 2010-08-27 2020-04-22 Hyalex Orthopaedics, Inc. Réseaux de polymère hydrophobe et hydrophile interpénétrant dérivés de polymères hydrophobes et procédés de préparation de ceux-ci
US20130103157A1 (en) 2011-10-03 2013-04-25 Lampros Kourtis Polymeric adhesive for anchoring compliant materials to another surface
EP3335673A1 (fr) 2011-11-21 2018-06-20 Biomimedica, Inc Systèmes d'ancrage d'implants orthopédiques aux os
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3617344A (en) * 1966-08-05 1971-11-02 Us Health Education & Welfare Nonthrombogenic plastic surfaces and preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3617344A (en) * 1966-08-05 1971-11-02 Us Health Education & Welfare Nonthrombogenic plastic surfaces and preparation thereof

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399836A1 (fr) * 1977-07-27 1979-03-09 Snam Progetti Procede de preparation de produits biocompatibles et articles ainsi obtenus
FR2410013A1 (fr) * 1977-11-23 1979-06-22 Unitika Ltd Procede pour preparer un article polymere antithrombogene
FR2440733A1 (fr) * 1978-11-08 1980-06-06 Fydelor Peter Dispositif chirurgical biologiquement compatible, comprenant une matiere plastique
EP0029411A1 (fr) * 1979-11-15 1981-05-27 Battelle Memorial Institute Composition adhésive pour le dépôt d'un revêtement adhésif fixateur de molécules biofonctionnelles, revêtement obtenu et procédé pour sa préparation, substrat recouvert du revêtement et son utilisation comme biocatalyseur
WO1981001412A1 (fr) * 1979-11-15 1981-05-28 Battelle Memorial Institute Composition adhesive fixateur de molecules biofonctionnelles
EP0091128A3 (en) * 1982-04-06 1984-09-12 The State Of Israel Atomic Energy Commission Soreq Nucle Synthetic wound covering
EP0091128A2 (fr) * 1982-04-06 1983-10-12 THE STATE of ISRAEL Atomic Energy Commission Soreq Nuclear Research Center Matériau synthétique pour le recouvrement des plaies
FR2534486A1 (fr) * 1982-10-15 1984-04-20 Commissariat Energie Atomique Support particulaire greffe en surface, son procede de preparation et adsorbants pour chromatographie d'affinite incorporant ce support, ainsi que leur utilisation, notamment en biologie
EP0106769A1 (fr) * 1982-10-15 1984-04-25 Commissariat à l'Energie Atomique Support particulaire greffé en surface, son procédé de préparation et adsorbants pour chromatographie d'affinité incorporant ce support, ainsi que leur utilisation, notamment en biologie
EP0109943A3 (en) * 1982-10-18 1985-08-14 Pharmacia Ab A method of forming polymeric layers
EP0109943A2 (fr) * 1982-10-18 1984-05-30 Pharmacia Ab Procédé pour préparer des couches polymères
EP0225867A2 (fr) * 1982-12-02 1987-06-16 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant et procédé de préparation
EP0110409A2 (fr) * 1982-12-02 1984-06-13 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant et procédé pour le préparer
EP0110409A3 (en) * 1982-12-02 1985-05-15 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbent and process for preparing the same
EP0464872B1 (fr) * 1982-12-02 2000-08-30 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant et procédé de sa préparation
EP0464872A1 (fr) * 1982-12-02 1992-01-08 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant et procédé de sa préparation
EP0225867A3 (en) * 1982-12-02 1988-02-24 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbent and process for preparing the same
FR2553518A1 (fr) * 1983-10-13 1985-04-19 Choay Sa Nouveaux conjugues elabores par fixation d'un ligand sur un support insoluble, leur preparation et leurs applications biologiques
EP0141711A2 (fr) * 1983-10-13 1985-05-15 Choay S.A. Nouveaux conjugués élaborés par fixation d'un ligand sur un support insoluble, leur préparation et leurs applications biologiques
EP0141711A3 (fr) * 1983-10-13 1985-06-26 Choay S.A. Nouveaux conjugués élaborés par fixation d'un ligand sur un support insoluble, leur préparation et leurs applications biologiques
EP0152699A2 (fr) * 1984-02-10 1985-08-28 Deseret Medical, Inc. Polymère de polyuréthane antithrombogène et procédé d'attribution d'activité antithrombogène à un substrat de polyuréthane
EP0152699A3 (en) * 1984-02-10 1987-01-28 Warner-Lambert Company An antithrombogenic polyurethane polymer and a process for imparting antithrombogenic activity to a polyurethane substrate
EP0200295A3 (en) * 1985-04-01 1987-02-25 Warner-Lambert Company Antithrombogenic polyurethane surface
EP0200295A2 (fr) * 1985-04-01 1986-11-05 Deseret Medical, Inc. Surface antithrombogène en polyuréthane
WO1987000060A1 (fr) * 1985-07-08 1987-01-15 Battelle Memorial Institute Substrat dont la surface presente une activite antithrombogenique
US4987181A (en) * 1985-07-08 1991-01-22 Battelle Memorial Institute Substrate with an antithromogenic active surface
EP0290642A1 (fr) * 1987-05-12 1988-11-17 Mittermayer, Christian, Dr. med. Procédé pour ensemencer des surfaces polymériques avec des cellules endothéliales humaines
US5061750A (en) * 1987-06-09 1991-10-29 Cordis Europa N.V. Covalent attachment of anticoagulants and the like onto biomaterials
EP0294905A1 (fr) * 1987-06-09 1988-12-14 Cordis Europa N.V. Fixation covalente d'anticoagulants et produits semblables aux matériaux biocompatibles
EP0428569A1 (fr) * 1988-08-03 1991-05-29 New England Deaconess Hospital Substance biocompatible a thromboresistance
EP0428569A4 (en) * 1988-08-03 1992-02-05 New England Deaconess Hospital Biocompatible substance with thromboresistance
NL9000362A (nl) * 1990-02-15 1991-09-02 Cordis Corp Werkwijze voor het aktiveren van een oppervlak van een substraat voor het koppelbaar maken van het oppervlak aan een door covalente binding op het oppervlak te immobiliseren materiaal, alsmede substraat, voorzien van een geaktiveerd oppervlak.
WO1991016932A1 (fr) * 1990-04-27 1991-11-14 Biocompatibles Limited Polymeres antithrombogenes
EP0608095A1 (fr) * 1993-01-19 1994-07-27 Medtronic, Inc. Fixation de biomolécules
FR2785812A1 (fr) * 1998-11-16 2000-05-19 Commissariat Energie Atomique Protheses bioactives, notamment a proprietes immunosuppressives, antistenose et antithrombose, et leur fabrication
WO2000029043A1 (fr) * 1998-11-16 2000-05-25 Commissariat A L'energie Atomique Protheses bioactives a proprietes immunosuppressives, antistenose et antithrombose
US6517858B1 (en) 1998-11-16 2003-02-11 Commissariat A L'energie Atomique Bioactive prostheses with immunosuppressive, antistenotic and antithrombotic properties

Also Published As

Publication number Publication date
SE400565B (sv) 1978-04-03
US3826678A (en) 1974-07-30
JPS4951386A (fr) 1974-05-18
NO140429B (no) 1979-05-21
DE2326863A1 (de) 1973-12-20
NO140429C (no) 1979-08-29
GB1391028A (en) 1975-04-16
CH593064A5 (fr) 1977-11-15
FR2187849B1 (fr) 1977-12-30
BE800536A (fr) 1973-10-01
JPS5736921B2 (fr) 1982-08-06

Similar Documents

Publication Publication Date Title
FR2213168B1 (fr)
FR2206819A5 (fr)
JPS5216645B2 (fr)
JPS4975340A (fr)
JPS4940712A (fr)
JPS4920827U (fr)
JPS539344Y2 (fr)
JPS4991155U (fr)
JPS4917759U (fr)
JPS4954646U (fr)
JPS49100040U (fr)
JPS4895169A (fr)
JPS48113930U (fr)
JPS48109621U (fr)
HU166509B (fr)
JPS4926974U (fr)
JPS4960953U (fr)
JPS4993549U (fr)
JPS4928373A (fr)
CH570655A5 (fr)
CH581183A5 (fr)
CH590344A5 (fr)
CH590289A5 (fr)
CH589764A5 (fr)
CH590493A5 (fr)

Legal Events

Date Code Title Description
ST Notification of lapse