FR2382238A1 - Procede de purification de l'antigene de l'hepatite b, et produits obtenus - Google Patents

Procede de purification de l'antigene de l'hepatite b, et produits obtenus

Info

Publication number
FR2382238A1
FR2382238A1 FR7706090A FR7706090A FR2382238A1 FR 2382238 A1 FR2382238 A1 FR 2382238A1 FR 7706090 A FR7706090 A FR 7706090A FR 7706090 A FR7706090 A FR 7706090A FR 2382238 A1 FR2382238 A1 FR 2382238A1
Authority
FR
France
Prior art keywords
hepatitis
antigen
purifying
products obtained
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7706090A
Other languages
English (en)
French (fr)
Other versions
FR2382238B1 (cs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2382238A1 publication Critical patent/FR2382238A1/fr
Application granted granted Critical
Publication of FR2382238B1 publication Critical patent/FR2382238B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Centrifugal Separators (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FR7706090A 1977-02-23 1977-03-02 Procede de purification de l'antigene de l'hepatite b, et produits obtenus Granted FR2382238A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7657/77A GB1554811A (en) 1977-02-23 1977-02-23 Purifying hepatitis b surface antigen

Publications (2)

Publication Number Publication Date
FR2382238A1 true FR2382238A1 (fr) 1978-09-29
FR2382238B1 FR2382238B1 (cs) 1981-05-29

Family

ID=9837320

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7706090A Granted FR2382238A1 (fr) 1977-02-23 1977-03-02 Procede de purification de l'antigene de l'hepatite b, et produits obtenus

Country Status (6)

Country Link
JP (2) JPS53115812A (cs)
CA (1) CA1088426A (cs)
CH (1) CH636269A5 (cs)
DE (1) DE2709581A1 (cs)
FR (1) FR2382238A1 (cs)
GB (1) GB1554811A (cs)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2394297A1 (fr) * 1976-11-02 1979-01-12 Merck & Co Inc Particules de dane de l'hepatite b
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
US4029764A (en) * 1974-12-09 1977-06-14 Merck & Co., Inc. Hepatitis A antigen
US4017360A (en) * 1975-05-14 1977-04-12 Merck & Co., Inc. Method for purifying hepatitis B antigen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2394297A1 (fr) * 1976-11-02 1979-01-12 Merck & Co Inc Particules de dane de l'hepatite b
FR2422406A1 (fr) * 1976-11-02 1979-11-09 Merck & Co Inc Composition comprenant un concentrat de particules de dane
FR2422399A1 (fr) * 1976-11-02 1979-11-09 Merck & Co Inc Procede pour la concentration de particules de dane par fractionnement isopycnique
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Also Published As

Publication number Publication date
JPS58180431A (ja) 1983-10-21
CA1088426A (en) 1980-10-28
DE2709581C2 (cs) 1988-04-07
DE2709581A1 (de) 1978-09-07
FR2382238B1 (cs) 1981-05-29
GB1554811A (en) 1979-10-31
JPS53115812A (en) 1978-10-09
CH636269A5 (en) 1983-05-31
JPS6313969B2 (cs) 1988-03-29

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Legal Events

Date Code Title Description
ST Notification of lapse