FR2381056A1 - Nouveaux derives de vinylorganoetain utiles comme intermediaires de synthese des prostaglandines et leur procede de preparation - Google Patents

Nouveaux derives de vinylorganoetain utiles comme intermediaires de synthese des prostaglandines et leur procede de preparation

Info

Publication number
FR2381056A1
FR2381056A1 FR7805108A FR7805108A FR2381056A1 FR 2381056 A1 FR2381056 A1 FR 2381056A1 FR 7805108 A FR7805108 A FR 7805108A FR 7805108 A FR7805108 A FR 7805108A FR 2381056 A1 FR2381056 A1 FR 2381056A1
Authority
FR
France
Prior art keywords
vinylorganoetain
new
preparation process
prostaglandin synthesis
derivatives useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7805108A
Other languages
English (en)
Other versions
FR2381056B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2381056A1 publication Critical patent/FR2381056A1/fr
Application granted granted Critical
Publication of FR2381056B1 publication Critical patent/FR2381056B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne de nouveaux intermédiaires de synthèse des prostaglandines de formule générale :
FR7805108A 1977-02-22 1978-02-22 Nouveaux derives de vinylorganoetain utiles comme intermediaires de synthese des prostaglandines et leur procede de preparation Granted FR2381056A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/770,536 US4151187A (en) 1977-02-22 1977-02-22 Intermediates for prostaglandin synthesis

Publications (2)

Publication Number Publication Date
FR2381056A1 true FR2381056A1 (fr) 1978-09-15
FR2381056B1 FR2381056B1 (fr) 1984-06-08

Family

ID=25088891

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7805108A Granted FR2381056A1 (fr) 1977-02-22 1978-02-22 Nouveaux derives de vinylorganoetain utiles comme intermediaires de synthese des prostaglandines et leur procede de preparation

Country Status (6)

Country Link
US (1) US4151187A (fr)
JP (1) JPS53108928A (fr)
CA (1) CA1140933A (fr)
DE (1) DE2807264A1 (fr)
FR (1) FR2381056A1 (fr)
GB (1) GB1571756A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329809C (fr) * 1987-07-08 1994-05-24 Nissan Chemical Industries, Ltd. Alcool allylque optiquement actif et procede pour la production de leucotriene b_ et son utilisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061670A (en) * 1976-07-19 1977-12-06 American Cyanamid Company 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners
US4038308A (en) * 1976-09-13 1977-07-26 American Home Products Corporation Prostaglandin derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, volume 69, no. 13, 23 september 1968, réf. 52240x, COLUMBUS, OHIO (US), & Zh.Obshch.Khim. 1968, 38 (1), 203 - 204, MAL'TSEVA E.N. et al.: 'Unsaturated tin hydrocarbons.Action of triethyltin hydride on enynes' *

Also Published As

Publication number Publication date
DE2807264C2 (fr) 1988-02-25
JPH0115517B2 (fr) 1989-03-17
CA1140933A (fr) 1983-02-08
DE2807264A1 (de) 1978-08-24
US4151187A (en) 1979-04-24
JPS53108928A (en) 1978-09-22
GB1571756A (en) 1980-07-16
FR2381056B1 (fr) 1984-06-08

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Legal Events

Date Code Title Description
ST Notification of lapse