FR2381048B1 - - Google Patents

Info

Publication number
FR2381048B1
FR2381048B1 FR7705067A FR7705067A FR2381048B1 FR 2381048 B1 FR2381048 B1 FR 2381048B1 FR 7705067 A FR7705067 A FR 7705067A FR 7705067 A FR7705067 A FR 7705067A FR 2381048 B1 FR2381048 B1 FR 2381048B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7705067A
Other versions
FR2381048A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7705067A priority Critical patent/FR2381048A1/fr
Priority to SE7801153A priority patent/SE436356B/sv
Priority to IL54069A priority patent/IL54069A/xx
Priority to AT121178A priority patent/AT357274B/de
Priority to NLAANVRAGE7801887,A priority patent/NL187397C/xx
Priority to GB6874/78A priority patent/GB1596207A/en
Priority to HU78RO965A priority patent/HU176707B/hu
Priority to ES467185A priority patent/ES467185A1/es
Priority to BE185355A priority patent/BE864173A/fr
Priority to DK075878A priority patent/DK151805C/da
Priority to PT67686A priority patent/PT67686B/fr
Priority to MX786873U priority patent/MX5256E/es
Priority to IE377/78A priority patent/IE46466B1/en
Priority to AU33469/78A priority patent/AU514033B2/en
Priority to ZA00781020A priority patent/ZA781020B/xx
Priority to CA297,373A priority patent/CA1095520A/fr
Priority to MX1050278U priority patent/MX7077E/es
Priority to LU79099A priority patent/LU79099A1/fr
Priority to JP53018636A priority patent/JPS6031833B2/ja
Priority to CH193078A priority patent/CH627648A5/fr
Priority to DE19782807643 priority patent/DE2807643A1/de
Publication of FR2381048A1 publication Critical patent/FR2381048A1/fr
Priority to ES476866A priority patent/ES476866A1/es
Priority to US06/137,913 priority patent/US4291038A/en
Application granted granted Critical
Publication of FR2381048B1 publication Critical patent/FR2381048B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7705067A 1977-02-22 1977-02-22 Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments Granted FR2381048A1 (fr)

Priority Applications (23)

Application Number Priority Date Filing Date Title
FR7705067A FR2381048A1 (fr) 1977-02-22 1977-02-22 Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
SE7801153A SE436356B (sv) 1977-02-22 1978-01-31 Analogiforfarande for framstellning av 20,21-dinoreburnameninderivat
IL54069A IL54069A (en) 1977-02-22 1978-02-17 14,15-dihydro-20,21-dinoreburnamenin-14-ol derivatives,process for preparing them and pharmaceutical compositions containing them
NLAANVRAGE7801887,A NL187397C (nl) 1977-02-22 1978-02-20 Farmaceutische preparaten, 20,21-dinoreburnamenineverbindingen daarvoor en werkwijze voor hun bereiding.
AT121178A AT357274B (de) 1977-02-22 1978-02-20 Verfahren zur herstellung von neuen derivaten des 20,21-dinoreburnamenins
MX1050278U MX7077E (es) 1977-02-22 1978-02-21 Procedimiento para la preparacion de isomeros a de derivados de 20,21-dinoreburnamenina
ES467185A ES467185A1 (es) 1977-02-22 1978-02-21 Procedimiento de preparacion de nuevos derivados de 20,21. dinoreburnamenina.
BE185355A BE864173A (fr) 1977-02-22 1978-02-21 Nouveaux derives de 20,21-dinoreburnamenine, procede de preparation et compositions pharmaceutiques
DK075878A DK151805C (da) 1977-02-22 1978-02-21 Analogifremgangsmaade til fremstilling af 20,21-di-nor-eburnameninderivater eller farmaceutisk acceptable additionssalte deraf
PT67686A PT67686B (fr) 1977-02-22 1978-02-21 Procede de preparation de nouveaux derives de 20-21-dinoreburnamenine
MX786873U MX5256E (es) 1977-02-22 1978-02-21 Procedimiento para la preparacion de derivados de 20,21-dinoreburnamenina
IE377/78A IE46466B1 (en) 1977-02-22 1978-02-21 14, 15 - dihydro - 20, 21 -dinoreburnamenin - 14 - ols
GB6874/78A GB1596207A (en) 1977-02-22 1978-02-21 14,15-digydro-20,21-dinoreburnamenine-14-ols
ZA00781020A ZA781020B (en) 1977-02-22 1978-02-21 New 20,21-dinoreburnamenine derivatives,process for preparing them and pharmaceutical compositions
CA297,373A CA1095520A (fr) 1977-02-22 1978-02-21 Procede de preparation de nouveaux derives de 20,21- dinoreburnamenine
HU78RO965A HU176707B (en) 1977-02-22 1978-02-21 Process for producing 14,15-dihydro-20,21-dinor-eburnamenine-14-ol-isomeres
LU79099A LU79099A1 (fr) 1977-02-22 1978-02-21 Procede de preparation de nouveaux derives de 20,21-dinoreburnamenine
AU33469/78A AU514033B2 (en) 1977-02-22 1978-02-21 New 20, 21-dinoreburnamenine derivatives, process for preparing them and pharmaceutical compositions
JP53018636A JPS6031833B2 (ja) 1977-02-22 1978-02-22 新規な２０，２１↓−ジノルエブルナメニン誘導体、その製造法及び製薬組成物
CH193078A CH627648A5 (fr) 1977-02-22 1978-02-22 Nouveaux derives de 20,21-dinoreburnamenine, procede de preparation et compositions pharmaceutiques.
DE19782807643 DE2807643A1 (de) 1977-02-22 1978-02-22 Neue derivate des 20,21-dinoreburnamenins, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
ES476866A ES476866A1 (es) 1977-02-22 1979-01-15 Procedimiento de preparacion de isomeros a de nuevos deriva-dos de 20,21-dinoreburnamenina.
US06/137,913 US4291038A (en) 1977-02-22 1980-04-07 Cerebral vasodilating 20,21-dinoreburnamenine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7705067A FR2381048A1 (fr) 1977-02-22 1977-02-22 Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2381048A1 FR2381048A1 (fr) 1978-09-15
FR2381048B1 true FR2381048B1 (fr) 1980-12-19

Family

ID=9187054

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7705067A Granted FR2381048A1 (fr) 1977-02-22 1977-02-22 Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments

Country Status (20)

Country Link
US (1) US4291038A (fr)
JP (1) JPS6031833B2 (fr)
AT (1) AT357274B (fr)
BE (1) BE864173A (fr)
CA (1) CA1095520A (fr)
CH (1) CH627648A5 (fr)
DE (1) DE2807643A1 (fr)
DK (1) DK151805C (fr)
ES (2) ES467185A1 (fr)
FR (1) FR2381048A1 (fr)
GB (1) GB1596207A (fr)
HU (1) HU176707B (fr)
IE (1) IE46466B1 (fr)
IL (1) IL54069A (fr)
LU (1) LU79099A1 (fr)
MX (1) MX5256E (fr)
NL (1) NL187397C (fr)
PT (1) PT67686B (fr)
SE (1) SE436356B (fr)
ZA (1) ZA781020B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433528A2 (fr) * 1978-08-16 1980-03-14 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
JPS55100383A (en) * 1979-01-25 1980-07-31 Sumitomo Chem Co Ltd Preparation of novel nitrogen-containing polycyclic compound
FR2514357A1 (fr) * 1981-10-08 1983-04-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine eventuellement substitues sur le cycle e, procede de preparation et application comme medicaments
HU187139B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new eburnan derivatives
JPH0523158Y2 (fr) * 1986-01-28 1993-06-14
FR2623503B1 (fr) * 1987-11-19 1991-04-05 Roussel Uclaf
FR2623501B1 (fr) * 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2731154B1 (fr) * 1995-03-03 1997-05-09 Roussel Uclaf Compositions pharmaceutiques comprenant des derives de dinoreburnamenine
FR2865650B1 (fr) * 2004-01-30 2008-06-13 Biocortech Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil
FR2865649A1 (fr) * 2004-01-30 2005-08-05 Biocortech Utilisation du 14,15-dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures
FR2869034B1 (fr) * 2004-04-14 2008-04-04 Biocortech Soc Par Actions Sim Derive du 14,15-dihydro 20,21-dinoreburnamenin 14-ol et leur utilisation pour le traitement des depressions
FR2926077A1 (fr) 2008-01-04 2009-07-10 Servier Lab Nouveaux derives d'1h-indol-1-yl uree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118770B (da) * 1967-08-23 1970-10-05 Richter Gedeon Vegyeszet Fremgangsmåde til fremstilling af vincanol.
US3542796A (en) * 1969-07-07 1970-11-24 Miles Lab Certain hexahydro-1,12-trimethylene-indolo(2,3-a)quinolizines
FR2081587B1 (fr) * 1970-03-26 1973-04-06 Anvar
FR2168853B1 (fr) * 1972-01-24 1975-04-25 Centre Etd Ind Pharma
HU166766B (fr) * 1972-12-08 1975-05-28
JPS5147720A (fr) * 1974-10-22 1976-04-23 Komatsu Mfg Co Ltd

Also Published As

Publication number Publication date
AT357274B (de) 1980-06-25
ES467185A1 (es) 1979-06-16
ATA121178A (de) 1979-11-15
CH627648A5 (fr) 1982-01-29
DE2807643A1 (de) 1978-08-24
IL54069A (en) 1982-01-31
SE436356B (sv) 1984-12-03
ZA781020B (en) 1979-03-28
NL187397C (nl) 1991-09-16
DE2807643C2 (fr) 1992-04-09
MX5256E (es) 1983-05-23
GB1596207A (en) 1981-08-19
DK75878A (da) 1978-08-23
SE7801153L (sv) 1978-08-23
CA1095520A (fr) 1981-02-10
BE864173A (fr) 1978-08-21
IE46466B1 (en) 1983-06-15
FR2381048A1 (fr) 1978-09-15
AU3346978A (en) 1979-08-30
JPS6031833B2 (ja) 1985-07-24
IE780377L (en) 1978-08-22
JPS53103500A (en) 1978-09-08
US4291038A (en) 1981-09-22
PT67686A (fr) 1979-05-16
NL187397B (nl) 1991-04-16
IL54069A0 (en) 1978-04-30
HU176707B (en) 1981-04-28
DK151805B (da) 1988-01-04
DK151805C (da) 1988-06-13
LU79099A1 (fr) 1978-09-28
ES476866A1 (es) 1980-03-01
PT67686B (fr) 1980-03-04
NL7801887A (nl) 1978-08-24

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