FR2380279A1 - Quinazolinones condensees ayant une activite anti-inflammatoire et analgesique et procedes pour leur preparation - Google Patents

Quinazolinones condensees ayant une activite anti-inflammatoire et analgesique et procedes pour leur preparation

Info

Publication number
FR2380279A1
FR2380279A1 FR7803481A FR7803481A FR2380279A1 FR 2380279 A1 FR2380279 A1 FR 2380279A1 FR 7803481 A FR7803481 A FR 7803481A FR 7803481 A FR7803481 A FR 7803481A FR 2380279 A1 FR2380279 A1 FR 2380279A1
Authority
FR
France
Prior art keywords
inflammatory
quinazolines
analgesic activity
quinazolinones
condensed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7803481A
Other languages
English (en)
Other versions
FR2380279B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of FR2380279A1 publication Critical patent/FR2380279A1/fr
Application granted granted Critical
Publication of FR2380279B1 publication Critical patent/FR2380279B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Des quinazolines tricycliques notamment des 4,5-dihydro-5-arylimidazo-Ø1,2-aõ-quinazolines, 4,5-dihydro-5-aryl-s-triazolo-Ø4,3-aõ-quinazolines et 4,5-dihydro-5-aryltétrazolo-Ø1,5-aõ-quinazolines, et leurs sels formés par addition d'acides pharmaceutiquement acceptables, sont préparés par exemple par réduction des composés 4,5-insaturés correspondants, puis, si nécessaire, par alcoylation des composés ainsi produits. Ces substances ont une activité anti-inflammatoire et analgésique et sont utiles par exemple pour traiter les oedèmes.
FR7803481A 1977-02-09 1978-02-08 Quinazolinones condensees ayant une activite anti-inflammatoire et analgesique et procedes pour leur preparation Granted FR2380279A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1381877A JPS5398997A (en) 1977-02-09 1977-02-09 Fused pyridine derivertives and process for their preparation

Publications (2)

Publication Number Publication Date
FR2380279A1 true FR2380279A1 (fr) 1978-09-08
FR2380279B1 FR2380279B1 (fr) 1981-03-27

Family

ID=11843853

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7803481A Granted FR2380279A1 (fr) 1977-02-09 1978-02-08 Quinazolinones condensees ayant une activite anti-inflammatoire et analgesique et procedes pour leur preparation

Country Status (9)

Country Link
US (1) US4183932A (fr)
JP (1) JPS5398997A (fr)
AT (1) AT360027B (fr)
BE (1) BE863744A (fr)
CA (1) CA1089853A (fr)
CH (1) CH637961A5 (fr)
DE (1) DE2805124A1 (fr)
FR (1) FR2380279A1 (fr)
GB (1) GB1561375A (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW16481A1 (en) * 1980-08-15 1982-03-10 Hoffmann La Roche Novel imidazoquinazoline derivatives
FR2514765A1 (fr) * 1981-10-21 1983-04-22 Sanofi Sa Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central
CH657131A5 (de) * 1982-04-22 1986-08-15 Ciba Geigy Ag Chromogene dihydrochinazoline und ihre herstellung und verwendung.
US4469868A (en) * 1982-05-24 1984-09-04 Warner-Lambert Company Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines
WO1997042192A1 (fr) * 1996-05-07 1997-11-13 Basf Aktiengesellschaft Imidazoquinazolines, agents les contenant et leur utilisation dans la lutte contre les champignons nuisibles et les parasites animaux
DE10019714A1 (de) * 2000-04-20 2002-01-10 Gruenenthal Gmbh Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
CA2669275C (fr) * 2006-11-22 2015-02-24 Sumitomo Chemical Company, Limited Substance capable d'inhiber la signalisation de la cytokinine
US8546394B2 (en) * 2007-04-17 2013-10-01 Bristol-Myers Squibb Company Substituted [1,2,4]triazolo[4,3-A]pyrazine 11-beta-hydroxysteroid dehydrogenase inhibitors
CN115197225B (zh) * 2021-09-03 2023-04-11 贵州大学 一种五元杂环并喹唑啉酮类化合物及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2125378A1 (fr) * 1971-02-11 1972-09-29 Aspro Nicholas Ltd
FR2261771A1 (fr) * 1974-02-27 1975-09-19 Sumitomo Chemical Co

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087422A (en) * 1974-09-05 1978-05-02 Imperial Chemical Industries Limited Pesticidal dihydrotetrazolo[1,5-a]quinazolines
GB1519765A (en) * 1974-09-05 1978-08-02 Ici Ltd Pesticidal dihydrotetrazolo(1,5a) quinazolines compositions and processes
GB1559803A (en) * 1975-08-14 1980-01-30 Ici Ltd Pesticidal dihydrotetrazoloquinazolines
US4085213A (en) * 1976-01-28 1978-04-18 Pfizer Inc. Tetrazolo[A]quinazol-5-ones antiallergy and antiulcer agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2125378A1 (fr) * 1971-02-11 1972-09-29 Aspro Nicholas Ltd
FR2261771A1 (fr) * 1974-02-27 1975-09-19 Sumitomo Chemical Co

Also Published As

Publication number Publication date
ATA88178A (de) 1980-05-15
US4183932A (en) 1980-01-15
FR2380279B1 (fr) 1981-03-27
GB1561375A (en) 1980-02-20
JPS5398997A (en) 1978-08-29
BE863744A (fr) 1978-05-29
CA1089853A (fr) 1980-11-18
DE2805124A1 (de) 1978-08-10
CH637961A5 (de) 1983-08-31
AT360027B (de) 1980-12-10

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Legal Events

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