FR2378759A1 - Procede pour la preparation de composes de derives d'indole - Google Patents

Procede pour la preparation de composes de derives d'indole

Info

Publication number
FR2378759A1
FR2378759A1 FR7718840A FR7718840A FR2378759A1 FR 2378759 A1 FR2378759 A1 FR 2378759A1 FR 7718840 A FR7718840 A FR 7718840A FR 7718840 A FR7718840 A FR 7718840A FR 2378759 A1 FR2378759 A1 FR 2378759A1
Authority
FR
France
Prior art keywords
preparation
compounds
indole derivatives
relates
tryptophanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7718840A
Other languages
English (en)
French (fr)
Inventor
Andrew David Batcho
Urs Oskar Hengartner
Willy Leimgruber
John William Scott
Donald Valentine Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2378759A1 publication Critical patent/FR2378759A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Seasonings (AREA)
FR7718840A 1976-06-22 1977-06-20 Procede pour la preparation de composes de derives d'indole Withdrawn FR2378759A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/698,573 US4073795A (en) 1976-06-22 1976-06-22 Synthesis of tryptophans

Publications (1)

Publication Number Publication Date
FR2378759A1 true FR2378759A1 (fr) 1978-08-25

Family

ID=24805823

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7718840A Withdrawn FR2378759A1 (fr) 1976-06-22 1977-06-20 Procede pour la preparation de composes de derives d'indole
FR7803668A Granted FR2378760A1 (fr) 1976-06-22 1978-02-09 Procede pour la preparation de composes de derives d'indole

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7803668A Granted FR2378760A1 (fr) 1976-06-22 1978-02-09 Procede pour la preparation de composes de derives d'indole

Country Status (9)

Country Link
US (2) US4073795A (enExample)
JP (1) JPS52156865A (enExample)
AT (1) AT360512B (enExample)
BE (1) BE855904A (enExample)
DE (1) DE2727671A1 (enExample)
FR (2) FR2378759A1 (enExample)
GB (2) GB1569341A (enExample)
IT (1) IT1143671B (enExample)
NL (1) NL7706906A (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256641A (en) * 1976-06-22 1981-03-17 Hoffmann-La Roche Inc. Novel syntheses of tryptophans
US4137404A (en) * 1977-12-20 1979-01-30 Hoffmann-La Roche Inc. Synthesis of tryptophans
US4198501A (en) * 1977-12-20 1980-04-15 Hoffmann-La Roche Inc. Synthesis of tryptophans
US4399289A (en) * 1980-03-31 1983-08-16 Toray Industries, Inc. 2-Diphenylmethyleneamino-3-indolylpropionitrile and alkyl esters of 2-diphenylmethylene-amino-3-indolylpropionic acid
DE3015113A1 (de) * 1980-04-19 1981-10-22 Dr. Karl Thomae Gmbh, 7950 Biberach 4-hydroxy-1,2-benzisothiazol-3(2h)-on-1,1-dioxide, ihre salze, ihre herstellung und verwendung
ATA61486A (de) * 1985-03-19 1992-05-15 Thomae Gmbh Dr K Verfahren zur herstellung von 4-hydroxy-1,2benzisothiazol-3(2h)-on-1,1-dioxid
US4757151A (en) * 1985-11-14 1988-07-12 Warner-Lambert Company 2-substituted-[2-substituted-amino]-N-arylalkyl-3-[indol-3-yl]
US5360814A (en) * 1991-02-28 1994-11-01 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
US5484814A (en) * 1991-02-28 1996-01-16 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
WO2006064340A2 (en) * 2004-12-13 2006-06-22 Pfizer Limited Process for the preparation of n-acyl beta-aminoaldehydes
USD536079S1 (en) * 2006-03-31 2007-01-30 Emerson Network Power, Energy Systems, North America, Inc. Evaporator air mover cover for DC cooler
USD575381S1 (en) 2006-03-31 2008-08-19 Emerson Network Power Condenser shroud for DC cooler
SI2828256T1 (sl) 2012-03-23 2019-11-29 Novartis Ag Kemijski postopek za pripravo spiroindolonov in njihovih vmesnih spojin
AR117958A1 (es) * 2018-12-11 2021-09-08 Heidelberg Pharma Res Gmbh Síntesis del (s)-6-hidroxitriptófano y derivados del mismo

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3026325A (en) * 1959-01-26 1962-03-20 Upjohn Co 5-hydroxy-alpha-alkyltryptophans
FR1457260A (fr) * 1961-08-18 1966-01-24 Merck & Co Inc Procédé de production d'amino-acides du type tryptophane
FR2002067A1 (fr) * 1968-02-16 1969-10-03 Upjohn Co Esters de alpha-alkyl-5-hydroxytryptophane,leur production et des compositions en contenant
US3627782A (en) * 1969-06-12 1971-12-14 Allied Chem Synthesis of gramine salt of nitroacetate esters

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2380479A (en) * 1941-06-06 1945-07-31 Eric T Stiller dl-tryptophane and processes for producing the same
CS152222B1 (enExample) 1970-05-29 1973-12-19
US3676458A (en) * 1970-06-11 1972-07-11 Lilly Co Eli (indolymethyl) malonate compound

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3026325A (en) * 1959-01-26 1962-03-20 Upjohn Co 5-hydroxy-alpha-alkyltryptophans
FR1457260A (fr) * 1961-08-18 1966-01-24 Merck & Co Inc Procédé de production d'amino-acides du type tryptophane
FR2002067A1 (fr) * 1968-02-16 1969-10-03 Upjohn Co Esters de alpha-alkyl-5-hydroxytryptophane,leur production et des compositions en contenant
US3627782A (en) * 1969-06-12 1971-12-14 Allied Chem Synthesis of gramine salt of nitroacetate esters

Also Published As

Publication number Publication date
IT1143671B (it) 1986-10-22
AT360512B (de) 1981-01-12
GB1569342A (en) 1980-06-11
FR2378760A1 (fr) 1978-08-25
BE855904A (fr) 1977-12-21
GB1569341A (en) 1980-06-11
ATA435977A (de) 1980-06-15
US4073795A (en) 1978-02-14
FR2378760B1 (enExample) 1980-01-18
NL7706906A (nl) 1977-12-27
DE2727671A1 (de) 1978-01-05
US4140697A (en) 1979-02-20
JPS52156865A (en) 1977-12-27

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Legal Events

Date Code Title Description
ST Notification of lapse