IT1143671B - Procedimento per la fabbricazione di triptofano e di suoi derivati - Google Patents

Procedimento per la fabbricazione di triptofano e di suoi derivati

Info

Publication number
IT1143671B
IT1143671B IT24583/77A IT2458377A IT1143671B IT 1143671 B IT1143671 B IT 1143671B IT 24583/77 A IT24583/77 A IT 24583/77A IT 2458377 A IT2458377 A IT 2458377A IT 1143671 B IT1143671 B IT 1143671B
Authority
IT
Italy
Prior art keywords
triptofano
derivatives
procedure
manufacture
Prior art date
Application number
IT24583/77A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of IT1143671B publication Critical patent/IT1143671B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT24583/77A 1976-06-22 1977-06-10 Procedimento per la fabbricazione di triptofano e di suoi derivati IT1143671B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/698,573 US4073795A (en) 1976-06-22 1976-06-22 Synthesis of tryptophans

Publications (1)

Publication Number Publication Date
IT1143671B true IT1143671B (it) 1986-10-22

Family

ID=24805823

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24583/77A IT1143671B (it) 1976-06-22 1977-06-10 Procedimento per la fabbricazione di triptofano e di suoi derivati

Country Status (9)

Country Link
US (2) US4073795A (it)
JP (1) JPS52156865A (it)
AT (1) AT360512B (it)
BE (1) BE855904A (it)
DE (1) DE2727671A1 (it)
FR (2) FR2378759A1 (it)
GB (2) GB1569342A (it)
IT (1) IT1143671B (it)
NL (1) NL7706906A (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256641A (en) * 1976-06-22 1981-03-17 Hoffmann-La Roche Inc. Novel syntheses of tryptophans
US4137404A (en) * 1977-12-20 1979-01-30 Hoffmann-La Roche Inc. Synthesis of tryptophans
US4198501A (en) * 1977-12-20 1980-04-15 Hoffmann-La Roche Inc. Synthesis of tryptophans
US4399289A (en) * 1980-03-31 1983-08-16 Toray Industries, Inc. 2-Diphenylmethyleneamino-3-indolylpropionitrile and alkyl esters of 2-diphenylmethylene-amino-3-indolylpropionic acid
DE3015113A1 (de) * 1980-04-19 1981-10-22 Dr. Karl Thomae Gmbh, 7950 Biberach 4-hydroxy-1,2-benzisothiazol-3(2h)-on-1,1-dioxide, ihre salze, ihre herstellung und verwendung
ATA61486A (de) * 1985-03-19 1992-05-15 Thomae Gmbh Dr K Verfahren zur herstellung von 4-hydroxy-1,2benzisothiazol-3(2h)-on-1,1-dioxid
US4757151A (en) * 1985-11-14 1988-07-12 Warner-Lambert Company 2-substituted-[2-substituted-amino]-N-arylalkyl-3-[indol-3-yl]
US5484814A (en) * 1991-02-28 1996-01-16 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
US5360814A (en) * 1991-02-28 1994-11-01 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
WO2006064340A2 (en) * 2004-12-13 2006-06-22 Pfizer Limited Process for the preparation of n-acyl beta-aminoaldehydes
EP2828256B1 (en) * 2012-03-23 2019-07-03 Novartis AG Chemical process for preparing spiroindolones and intermediates thereof
CA3118031A1 (en) * 2018-12-11 2020-06-18 Heidelberg Pharma Research Gmbh Synthesis of (s)-6-hydroxytryptophan and derivatives thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2380479A (en) * 1941-06-06 1945-07-31 Eric T Stiller dl-tryptophane and processes for producing the same
US3026325A (en) * 1959-01-26 1962-03-20 Upjohn Co 5-hydroxy-alpha-alkyltryptophans
FR1457260A (fr) * 1961-08-18 1966-01-24 Merck & Co Inc Procédé de production d'amino-acides du type tryptophane
GB1184538A (en) * 1968-02-16 1970-03-18 Upjohn Co alpha-Alkyl-5-Hydroxytryptophan Esters
US3627782A (en) * 1969-06-12 1971-12-14 Allied Chem Synthesis of gramine salt of nitroacetate esters
CS152222B1 (it) 1970-05-29 1973-12-19
US3676458A (en) * 1970-06-11 1972-07-11 Lilly Co Eli (indolymethyl) malonate compound

Also Published As

Publication number Publication date
GB1569342A (en) 1980-06-11
DE2727671A1 (de) 1978-01-05
US4140697A (en) 1979-02-20
BE855904A (fr) 1977-12-21
AT360512B (de) 1981-01-12
FR2378759A1 (fr) 1978-08-25
US4073795A (en) 1978-02-14
FR2378760A1 (fr) 1978-08-25
GB1569341A (en) 1980-06-11
NL7706906A (nl) 1977-12-27
JPS52156865A (en) 1977-12-27
ATA435977A (de) 1980-06-15
FR2378760B1 (it) 1980-01-18

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